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High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients 在未接种疫苗的新型冠状病毒肺炎患者中，高频率的 α 普通感冒冠状病毒/SARS-CoV-2交叉反应功能性CD4和CD8记忆T细胞与保护免受症状性和致命性SARS-CoV-2感染有关 Coulon, Pierre-Gregoire; Prakash, Swayam; Dhanushkodi, Nisha R.; Srivastava, Ruchi; Zayou, Latifa; Tifrea, Delia F.; Edwards, Robert A.; Figueroa, Cesar J.; Schubl, Sebastian D.; Hsieh, Lanny; Nesburn, Anthony B.; Kuppermann, Baruch D.; Bahraoui, Elmostafa; Vahed, Hawa; Gil, Daniel; Jones, Trevor M.; Ulmer, Jeffrey B.; Benmohamed, Lbachir 分享 收藏
Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern 基于高度保守的人B、CD4和CD8 T细胞表位的疫苗对多种SARS-CoV-2变异引起的严重感染、疾病和死亡的交叉保护作用 Prakash, Swayam; Dhanushkodi, Nisha R.; Zayou, Latifa; Ibraim, Izabela Coimbra; Quadiri, Afshana; Coulon, Pierre Gregoire; Tifrea, Delia F.; Suzer, Berfin; Shaik, Amin Mohammed; Chilukuri, Amruth; Edwards, Robert A.; Singer, Mahmoud; Vahed, Hawa; Nesburn, Anthony B.; Kuppermann, Baruch D.; Ulmer, Jeffrey B.; Gil, Daniel; Jones, Trevor M.; BenMohamed, Lbachir 分享 收藏
Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-2CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa 粘膜CCL28趋化因子通过动员抗病毒效应记忆CCR10 CD44 CD62L-2CD8 T细胞和记忆CCR10 B220 CD27 b细胞进入感染的阴道粘膜来改善对生殖器疱疹的保护 Dhanushkodi, Nisha Rajeswari; Prakash, Swayam; Quadiri, Afshana; Zayou, Latifa; Srivastava, Ruchi; Tran, Jennifer; Dang, Vivian; Shaik, Amin Mohammed; Chilukurri, Amruth; Suzer, Berfin; De Vera, Phil; Sun, Miyo; Nguyen, Pauline; Lee, Ashley; Salem, Amirah; Loi, Joyce; Singer, Mahmoud; Nakayama, Takashi; Vahed, Hawa; Nesburn, Anthony B.; BenMohamed, Lbachir 分享 收藏
Differential Epigenetic Status and Responses to Stressors between Retinal Cybrids Cells with African versus European Mitochondrial DNA: Insights into Disease Susceptibilities Atilano, Shari R.; Abedi, Sina; Ianopol, Narcisa, V; Singh, Mithalesh K.; Norman, J. Lucas; Malik, Deepika; Falatoonzadeh, Payam; Chwa, Marilyn; Nesburn, Anthony B.; Kuppermann, Baruch D.; Kenney, M. Cristina 分享 收藏
Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines Prakash, Swayam; Srivastava, Ruchi; Coulon, Pierre-Gregoire; Dhanushkodi, Nisha R.; Chentoufi, Aziz A.; Tifrea, Delia F.; Edwards, Robert A.; Figueroa, Cesar J.; Schubl, Sebastian D.; Hsieh, Lanny; Buchmeier, Michael J.; Bouziane, Mohammed; Nesburn, Anthony B.; Kuppermann, Baruch D.; BenMohamed, Lbachir 分享 收藏
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Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection Srivastava, Ruchi; Khan, Arif A.; Garg, Sumit; Syed, Sabrina A.; Furness, Julie N.; Vahed, Hawa; Pham, Tiffany; Yu, Howard T.; Nesburn, Anthony B.; BenMohamed, Lbachir 分享 收藏
Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA Thaker, Kunal; Chwa, Marilyn; Atilano, Shari R.; Coskun, Pinar; Caceres-del-Carpio, Javier; Udar, Nitin; Boyer, David S.; Jazwinski, S. Michal; Miceli, Michael V.; Nesburn, Anthony B.; Kuppermann, Baruch D.; Kenney, M. Cristina 分享 收藏
The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits Srivastava, Ruchi; Dervillez, Xavier; Khan, Arif A.; Chentoufi, Aziz A.; Chilukuri, Sravya; Shukr, Nora; Fazli, Yasmin; Ong, Nicolas N.; Afifi, Rasha E.; Osorio, Nelson; Geertsema, Roger; Nesburn, Anthony B.; Wechsler, Steven L.; BenMohamed, Lbachir 分享 收藏
Therapeutic Immunization with a Mixture of Herpes Simplex Virus 1 Glycoprotein D-Derived Asymptomatic Human CD8+ T-Cell Epitopes Decreases Spontaneous Ocular Shedding in Latently Infected HLA Transgenic Rabbits: Association with Low Frequency of Local PD-1+ TIM-3+ CD8+ Exhausted T Cells Khan, Arif A.; Srivastava, Ruchi; Chentoufi, Aziz A.; Geertsema, Roger; Nhi Thi Uyen Thai; Dasgupta, Gargi; Osorio, Nelson; Kalantari, Mina; Nesburn, Anthony B.; Wechsler, Steven L.; BenMohameda, Lbachir 分享 收藏
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Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes Atilano, Shari R.; Malik, Deepika; Chwa, Marilyn; Caceres-Del-Carpio, Javier; Nesburn, Anthony B.; Boyer, David S.; Kuppermann, Baruch D.; Jazwinski, S. Michal; Miceli, Michael V.; Wallace, Douglas C.; Udar, Nitin; Kenney, M. Cristina 分享 收藏
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JOURNAL OF VIROLOGY