Steven M. Cramer - Publications, H-index & Citations

Steven M. Cramer

Johns Hopkins University

37H指数

219论文数

4.2K被引数

收录论文 62

发表时间

In silico mediated workflow for rapid development of downstream processing: Orthogonal product-related impurity removal for a Fc-containing therapeutic

JOURNAL OF CHROMATOGRAPHY A

IF4

2024-10-01

PREAI

Jang, Dongyoun; Altern, Scott H.; Cramer, Steven M.

Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing 影响产品关联的因素作为生物加工中宿主细胞蛋白质持久性的机制

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2024-01-19

PREAI

Oh, Young Hoon; Becker, Matthew L.; Mendola, Kerri M.; Choe, Leila H.; Min, Lie; Lee, Kelvin H.; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J.; Cramer, Steven M.; Menegatti, Stefano; Lenhoff, Abraham M.

Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing 单克隆抗体生物加工中CHO宿主细胞蛋白的鉴定和表征

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2023-10-25

PREAI

Oh, Young Hoon; Mendola, Kerri M.; Choe, Leila H.; Min, Lie; Lavoie, Ashton R.; Sripada, Sobhana A.; Williams, Taufika Islam; Lee, Kelvin H.; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J.; Cramer, Steven M.; Menegatti, Stefano; Lenhoff, Abraham M.

Continuous precipitation-filtration process for initial capture of a monoclonal antibody product using a four-stage countercurrent hollow fiber membrane washing step

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2023-08-10

OAAI

Minervini, Mirko; Mergy, Matthew; Zhu, Yuncan; Diaz, Mario Gutierrez A.; Pointer, Craig; Shinkazh, Oleg; Oppenheim, Sheldon F.; Cramer, Steven M.; Przybycien, Todd M.; Zydney, Andrew L.

Implications of AAV affinity column reuse and vector stability on product quality attributes

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2023-07-24

PREAI

Soni, Harshal; Lako, Ira; Placidi, Matteo; Cramer, Steven M.

Evaluation of preferred binding regions on ubiquitin and IgG1 FC for interacting with multimodal cation exchange resins using DEPC labeling/mass spectrometry

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2023-03-03

PREAI

Dhingra, Kabir; Gudhka, Ronak B.; Cramer, Steven M.

Characterization and implications of host-cell protein aggregates in biopharmaceutical processing 生物制药加工中宿主细胞蛋白聚集体的表征和意义

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2023-01-12

OAAI

Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine-Induced Immunity in Older Adults 老年人虚弱，年龄和生物学性别与新型冠状病毒信使RNA疫苗诱导的免疫力的关联

CLINICAL INFECTIOUS DISEASES

IF7.3

2022-05-24

OAAI

Shapiro, Janna R.; Sitaras, Ioannis; Park, Han Sol; Aytenfisu, Tihitina Y.; Caputo, Christopher; Li, Maggie; Lee, John; Johnston, Trevor S.; Li, Huifen; Wouters, Camille; Hauk, Pricila; Jacobsen, Henning; Li, Yukang; Abrams, Engle; Yoon, Steve; Kocot, Andrew J.; Yang, Tianrui; Huang, Yushu; Cramer, Steven M.; Betenbaugh, Michael J.; Debes, Amanda K.; Morgan, Rosemary; Milstone, Aaron M.; Karaba, Andrew H.; Pekosz, Andrew; Leng, Sean X.; Klein, Sabra L.

Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via flow-through affinity chromatography using peptide-based adsorbents 走向连续mAb纯化: 使用基于肽的吸附剂通过流通亲和色谱从CHO细胞培养收获物中清除宿主细胞蛋白

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2022-04-22

PREAI

Sripada, Sobhana Alekhya; Chu, Wenning; Williams, Taufika Islam; Teten, Matthew A.; Mosley, Brian J.; Carbonell, Ruben G.; Lenhoff, Abraham M.; Cramer, Steven M.; Bill, Jerome; Yigzaw, Yinges; Roush, David J.; Menegatti, Stefano

Development of QSAR models for in silico screening of antibody solubility

MABS

IF7.3

2022-04-20

OAAI

Han, Xuan; Shih, James; Lin, Yuhao; Chai, Qing; Cramer, Steven M.

Adaptive immune responses in vaccinated patients with symptomatic SARS-CoV-2 Alpha infection

JCI INSIGHT

IF6.1

2022-03-08

OAAI

Park, Han-Sol; Shapiro, Janna R.; Sitaras, Ioannis; Woldemeskel, Bezawit A.; Garliss, Caroline C.; Dziedzic, Amanda; Sachithanandham, Jaiprasath; Jedlicka, Anne E.; Caputo, Christopher A.; Rousseau, Kimberly E.; Thakar, Manjusha; Suwanmanee, San; Hauk, Pricila; Aliyu, Lateef; Majewska, Natalia, I; Koley, Sushmita; Patel, Bela; Broderick, Patrick; Mosnaim, Giselle; Heath, Sonya L.; Spivak, Emily S.; Shenoy, Aarthi; Bloch, Evan M.; Gniadek, Thomas J.; Shoham, Shmuel; Casadevall, Arturo; Hanley, Daniel; Cox, Andrea L.; Laeyendecker, Oliver; Betenbaugh, Michael J.; Cramer, Steven M.; Mostafa, Heba H.; Pekosz, Andrew; Blankson, Joel N.; Klein, Sabra L.; Tobian, Aaron A. R.; Sullivan, David; Gebo, Kelly A.

A framework for calculating orthogonal selectivities in multimodal systems directly from cell culture fluid

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2021-11-08

PREAI

Vecchiarello, Nicholas; Timmick, Steven M.; Cramer, Steven

Systematic workflow for studying domain contributions of bispecific antibodies to selectivity in multimodal chromatography

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2021-11-02

PREAI

Parasnavis, Siddharth S.; Niu, Ben; Aspelund, Matthew; Chung, Wai K.; Snyder, Mark; Cramer, Steven M.

Affinity precipitation of monoclonal antibodies using ELP-Z in the elution without resolubilization mode

JOURNAL OF BIOTECHNOLOGY

IF3.9

2021-09-01

PREAI

Bhat, Manish; Mullerpatan, Akshat; Chen, Jie; Holstein, Melissa; Ghose, Sanchayita; Li, Zheng Jian; Cramer, Steven

Advancing a rapid, high throughput screening platform for optimization of lentivirus production

BIOTECHNOLOGY JOURNAL

IF3.1

2021-07-21

PREAI

Gopal, Sneha; Osborne, Adam E.; Hock, Lindsay; Zemianek, Jill; Fang, Kun; Gee, Gretchen; Ghosh, Ronit; McNally, David; Cramer, Steven M.; Dordick, Jonathan S.

Rapid optimization of processes for the integrated purification of biopharmaceuticals

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2021-05-04

OAAI

Crowell, Laura E.; Rodriguez, Sergio A.; Love, Kerry R.; Cramer, Steven M.; Love, J. Christopher

Development of a platform process for the production and purification of single-domain antibodies

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2021-03-25

OAAI

Crowell, Laura E.; Goodwine, Chaz; Holt, Carla S.; Rocha, Lucia; Vega, Celina; Rodriguez, Sergio A.; Dalvie, Neil C.; Tracey, Mary K.; Puntel, Mariana; Wigdorovitz, Andres; Parreno, Viviana; Love, Kerry R.; Cramer, Steven M.; Love, J. Christopher

Identification of preferred multimodal ligand-binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2020-11-06

PREAI

Gudhka, Ronak B.; Bilodeau, Camille L.; McCallum, Scott A.; McCoy, Mark A.; Roush, David J.; Snyder, Mark A.; Cramer, Steven M.

Quantifying orthogonality and separability: A method for optimizing resin selection and design

JOURNAL OF CHROMATOGRAPHY A

IF4

2020-09-01

OAAI

Bilodeau, Camille L.; Vecchiarello, Nicholas A.; Altern, Scott; Cramer, Steven M.