未登录Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager
Yang, Zhuo; Hou, Yingqin; Grande, Geramie; Cho, Jong Hyun; Wang, Chao; Shi, Yujie; Zak, Jaroslav; Wan, Yue; Qin, Ke; Liu, Dongfang; Teijaro, John R.; Lerner, Richard A.; Wu, Peng .png)
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收藏Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cellsStepanov, Alexey V.; Xie, Jia; Zhu, Qiaoqiao; Shen, Zuyuan; Su, Wenji; Kuai, Letian; Soll, Richard; Rader, Christoph; Shaver, Geramie; Douthit, Lacey; Zhang, Ding; Kalinin, Roman; Fu, Xiang; Zhao, Yingying; Qin, Tian; Baran, Phil S.; Gabibov, Alexander G.; Bushnell, David; Neri, Dario; Kornberg, Roger D.; Lerner, Richard A. 分享 收藏 Switchable targeting of solid tumors by BsCAR T cellsBsCAR T细胞对实体瘤的可转换靶向Stepanov, Alexey V.; Kalinin, Roman S.; Shipunova, Victoria O.; Zhang, Ding; Xie, Jia; Rubtsov, Yuri P.; Ukrainskaya, Valeria M.; Schulga, Alexey; Konovalova, Elena V.; Volkov, Dmitry V.; Yaroshevich, Igor A.; Moysenovich, Anastasiia M.; Belogurov, Alexey A., Jr.; Zhang, Hongkai; Telegin, Georgij B.; Chernov, Alexandr S.; Maschan, Mikhail A.; Terekhov, Stanislav S.; Wu, Peng; Deyev, Sergey M.; Lerner, Richard A.; Gabibov, Alexander G.; Altman, Sidney 分享 收藏 Metal-Catalyzed One-Pot On-DNA Syntheses of Diarylmethane and Thioether DerivativesMa, Fei; Li, Jie; Zhang, Shuning; Gu, Yuang; Tan, Tingting; Chen, Wanting; Wang, Shuyue; Xu, Hongtao; Yang, Guang; Lerner, Richard A. 分享 收藏 Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades AgoQiang, Min; Ma, Peixiang; Li, Yu; Liu, Hejun; Harding, Adam; Min, Chenyu; Wang, Fulian; Liu, Lili; Yuan, Meng; Ji, Qun; Tao, Pingdong; Shi, Xiaojie; Li, Zhean; Li, Teng; Wang, Xian; Zhang, Yu; Wu, Nicholas C.; Lee, Chang-Chun D.; Zhu, Xueyong; Gilbert-Jaramillo, Javier; Zhang, Chuyue; Saxena, Abhishek; Huang, Xingxu; Wang, Hou; James, William; Dwek, Raymond A.; Wilson, Ian A.; Yang, Guang; Lerner, Richard A. 分享 收藏 Antigen-Specific Stimulation and Expansion of CAR-T Cells Using Membrane Vesicles as Target Cell Surrogates使用膜囊泡作为靶细胞替代物的car-t细胞的抗原特异性刺激和扩增Ukrainskaya, Valeria; Rubtsov, Yuri; Pershin, Dmitry; Podoplelova, Nadezhda; Terekhov, Stanislav; Yaroshevich, Igor; Sokolova, Anstasiia; Bagrov, Dmitry; Kulakovskaya, Elena; Shipunova, Victoria; Deyev, Sergey; Ziganshin, Rustam; Chernov, Aleksandr; Telegin, Georgii; Maksimov, Eugene; Markov, Oleg; Oshchepkova, Anastasiya; Zenkova, Marina; Xie, Jia; Zhang, Hongkai; Gabibov, Alexander; Maschan, Michael; Stepanov, Alexey; Lerner, Richard 分享 收藏 分享 收藏 Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications (vol 13, pg 540, 2021)Favalli, Nicholas; Bassi, Gabriele; Pellegrino, Christian; Millul, Jacopo; De Luca, Roberto; Cazzamalli, Samuele; Yang, Su; Trenner, Anika; Mozaffari, Nour L.; Myburgh, Renier; Moroglu, Mustafa; Conway, Stuart J.; Sartori, Alessandro A.; Manz, Markus G.; Lerner, Richard A.; Vogt, Peter K.; Scheuermann, Jorg; Neri, Dario 分享 收藏 Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptomsShi, Xiaojie; Wan, Yue; Wang, Nan; Xiang, Jiangchao; Wang, Tao; Yang, Xiaofeng; Wang, Ju; Dong, Xuxue; Dong, Liang; Yan, Lei; Li, Yu; Liu, Lili; Hou, Shinchen; Zhong, Zhenwei; Wilson, Ian A.; Yang, Bei; Yang, Guang; Lerner, Richard A. 分享 收藏 DNA-Encoded Libraries: Hydrazide as a Pluripotent Precursor for On-DNA Synthesis of Various Azole DerivativesMa, Fei; Li, Jie; Zhang, Shuning; Gu, Yuang; Tan, Tingting; Chen, Wanting; Wang, Shuyue; Ma, Peixiang; Xu, Hongtao; Yang, Guang; Lerner, Richard A. 分享 收藏 Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applicationsFavalli, Nicholas; Bassi, Gabriele; Pellegrino, Christian; Millul, Jacopo; De Luca, Roberto; Cazzamalli, Samuele; Yang, Su; Trenner, Anika; Mozaffari, Nour L.; Myburgh, Renier; Moroglu, Mustafa; Conway, Stuart J.; Sartori, Alessandro A.; Manz, Markus G.; Lerner, Richard A.; Vogt, Peter K.; Scheuermann, Jorg; Neri, Dario 分享 收藏 Avidity-Based Selection of Tissue-Specific CAR-T Cells from a Combinatorial Cellular Library of CARsMa, Peixiang; Ren, Ping; Zhang, Chuyue; Tang, Jiaxing; Yu, Zheng; Zhu, Xuekai; Fan, Kun; Li, Guanglei; Zhu, Wei; Sang, Wei; Min, Chenyu; Chen, Wenzhang; Huang, Xingxu; Yang, Guang; Lerner, Richard A. 分享 收藏 分享 收藏 Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengersMokrushina, Yuliana A.; Golovin, Andrey, V; Smirnov, Ivan, V; Chatziefthimiou, Spyros D.; Stepanova, Anastasia, V; Bobik, Tatyana, V; Zalevsky, Arthur O.; Zlobin, Alexander S.; Konovalov, Kirill A.; Terekhov, Stanislav S.; Stepanov, Alexey, V; Pipiya, Sofiya O.; Shamborant, Olga G.; Round, Ekaterina; Belogurov, Alexey A., Jr.; Bourenkov, Gleb; Makarov, Alexander A.; Wilmanns, Matthias; Xie, Jia; Blackburn, G. Michael; Gabibov, Alexander G.; Lerner, Richard A. 分享 收藏 A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant miceKuang, Yuanyua; Zorzi, Veronica; Buratto, Damiano; Ziraldo, Gaia; Mazzarda, Flavia; Peres, Chiara; Nardin, Chiara; Salvatore, Anna Maria; Chiani, Francesco; Scavizzi, Ferdinando; Raspa, Marcello; Qiang, Min; Chu, Youjun; Shi, Xiaojie; Li, Yu; Liu, Lili; Shi, Yaru; Zonta, Francesco; Yang, Guang; Lerner, Richard A.; Mammano, Fabio 分享 收藏 Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In VivoTao, Pingdong; Kuang, Yuanyuan; Li, Yu; Li, Wenping; Gao, Zibei; Liu, Lili; Qiang, Min; Zha, Zhao; Fan, Kun; Ma, Peixiang; Friedman, Jeffrey M.; Yang, Guang; Lerner, Richard A. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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