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PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation Wu, Rui; Sanishvili, Ruslan; Belitsky, Boris R.; Juncosa, Jose I.; Le, Hoang V.; Lehrer, Helaina J. S.; Farley, Michael; Silverman, Richard B.; Petsko, Gregory A.; Ringe, Dagmar; Liu, Dali 分享 收藏
Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites Liu, Ce Feng; Brandt, Gabriel S.; Hoang, Quyen Q.; Naumova, Natalia; Lazarevic, Vanja; Hwang, Eun Sook; Dekker, Job; Glimcher, Laurie H.; Ringe, Dagmar; Petsko, Gregory A. 分享 收藏
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Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein Wang, Wei; Nguyen, Linh T. T.; Burlak, Christopher; Chegini, Fariba; Guo, Feng; Chataway, Tim; Ju, Shulin; Fisher, Oriana S.; Miller, David W.; Datta, Debajyoti; Wu, Fang; Wu, Chun-Xiang; Landeru, Anuradha; Wells, James A.; Cookson, Mark R.; Boxer, Matthew B.; Thomas, Craig J.; Gai, Wei Ping; Ringe, Dagmar; Petsko, Gregory A.; Hoang, Quyen Q. 分享 收藏
Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease Kim, Chun-Hyung; Han, Baek-Soo; Moon, Jisook; Kim, Deog-Joong; Shin, Joon; Rajan, Sreekanth; Quoc Toan Nguyen; Sohn, Mijin; Kim, Won-Gon; Han, Minjoon; Jeong, Inhye; Kim, Kyoung-Shim; Lee, Eun-Hye; Tu, Yupeng; Naffin-Olivos, Jacqueline L.; Park, Chang-Hwan; Ringe, Dagmar; Yoon, Ho Sup; Petsko, Gregory A.; Kim, Kwang-Soo 分享 收藏
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 Barmada, Sami J.; Ju, Shulin; Arjun, Arpana; Batarse, Anthony; Archbold, Hilary C.; Peisach, Daniel; Li, Xingli; Zhang, Yuxi; Tank, Elizabeth M. H.; Qiu, Haiyan; Huang, Eric J.; Ringe, Dagmar; Petsko, Gregory A.; Finkbeiner, Steven 分享 收藏
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Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2 Naffin-Olivos, Jacqueline L.; Georgieva, Maria; Goldfarb, Nathan; Madan-Lala, Ranjna; Dong, Lauren; Bizzell, Erica; Valinetz, Ethan; Brandt, Gabriel S.; Yu, Sarah; Shabashvili, Daniil E.; Ringe, Dagmar; Dunn, Ben M.; Petsko, Gregory A.; Rengarajan, Jyothi 分享 收藏
Pharmacological chaperones stabilize retromer to limit APP processing Mecozzi, Vincent J.; Berman, Diego E.; Simoes, Sabrina; Vetanovetz, Chris; Awal, Mehraj R.; Patel, Vivek M.; Schneider, Remy T.; Petsko, Gregory A.; Ringe, Dagmar; Small, Scott A. 分享 收藏
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S- thiolation Auclair, Jared R.; Salisbury, Joseph P.; Johnson, Joshua L.; Petsko, Gregory A.; Ringe, Dagmar; Bosco, Daryl A.; Agar, Nathalie Y. R.; Santagata, Sandro; Durham, Heather D.; Agar, Jeffrey N. 分享 收藏
Structure of a eukaryotic thiaminase I Kreinbring, Cheryl A.; Remillard, Stephen P.; Hubbard, Paul; Brodkin, Heather R.; Leeper, Finian J.; Hawksley, Dan; Lai, Elaine Y.; Fulton, Chandler; Petsko, Gregory A.; Ringe, Dagmar 分享 收藏
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT Edayathumangalam, Raji; Wu, Rui; Garcia, Roman; Wang, Yuguang; Wang, Wei; Kreinbring, Cheryl A.; Bach, Alicia; Liao, Jingling; Stone, Todd A.; Terwilliger, Thomas C.; Hoang, Quyen Q.; Belitsky, Boris R.; Petsko, Gregory A.; Ringe, Dagmar; Liu, Dali 分享 收藏
Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site Sigala, Paul A.; Fafarman, Aaron T.; Schwans, Jason P.; Fried, Stephen D.; Fenn, Timothy D.; Caaveiro, Jose M. M.; Pybus, Brandon; Ringe, Dagmar; Petsko, Gregory A.; Boxer, Steven G.; Herschlag, Daniel 分享 收藏
Latrepirdine (Dimebon™) Enhances Autophagy and Reduces Intracellular GFP-Aβ42 Levels in Yeast Bharadwaj, Prashant R.; Verdile, Giuseppe; Barr, Renae K.; Gupta, Veer; Steele, John W.; Lachenmayer, M. Lenard; Yue, Zhenyu; Ehrlich, Michelle E.; Petsko, Gregory; Ju, Shulin; Ringe, Dagmar; Sankovich, Sonia E.; Caine, Joanne M.; Macreadie, Ian G.; Gandy, Sam; Martins, Ralph N. 分享 收藏
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain Steele, J. W.; Ju, S.; Lachenmayer, M. L.; Liken, J.; Stock, A.; Kim, S. H.; Delgado, L. M.; Alfaro, I. E.; Bernales, S.; Verdile, G.; Bharadwaj, P.; Gupta, V.; Barr, R.; Friss, A.; Dolios, G.; Wang, R.; Ringe, D.; Protter, A. A.; Martins, R. N.; Ehrlich, M. E.; Yue, Z.; Petsko, G. A.; Gandy, S. 分享 收藏
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model Steele, J. W.; Lachenmayer, M. L.; Ju, S.; Stock, A.; Liken, J.; Kim, S. H.; Delgado, L. M.; Alfaro, I. E.; Bernales, S.; Verdile, G.; Bharadwaj, P.; Gupta, V.; Barr, R.; Friss, A.; Dolios, G.; Wang, R.; Ringe, D.; Fraser, P.; Westaway, D.; St George-Hyslop, P. H.; Szabo, P.; Relkin, N. R.; Buxbaum, J. D.; Glabe, C. G.; Protter, A. A.; Martins, R. N.; Ehrlich, M. E.; Petsko, G. A.; Yue, Z.; Gandy, S. 分享 收藏
A soluble α-synuclein construct forms a dynamic tetramer Wang, Wei; Perovic, Iva; Chittuluru, Johnathan; Kaganovich, Alice; Nguyen, Linh T. T.; Liao, Jingling; Auclair, Jared R.; Johnson, Derrick; Landeru, Anuradha; Simorellis, Alana K.; Ju, Shulin; Cookson, Mark R.; Asturias, Francisco J.; Agar, Jeffrey N.; Webb, Brian N.; Kang, ChulHee; Ringe, Dagmar; Petsko, Gregory A.; Pochapsky, Thomas C.; Hoang, Quyen Q. 分享 收藏
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