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Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers Drilon, Alexander; Somwar, Romel; Mangatt, Biju P.; Edgren, Henrik; Desmeules, Patrice; Ruusulehto, Anja; Smith, Roger S.; Delasos, Lukas; Vojnic, Morana; Plodkowski, Andrew J.; Sabari, Joshua; Ng, Kenneth; Montecalvo, Joseph; Chang, Jason; Tai, Huichun; Lockwood, William W.; Martinez, Victor; Riely, Gregory J.; Rudin, Charles M.; Kris, Mark G.; Arcila, Maria E.; Matheny, Christopher; Benayed, Ryma; Rekhtman, Natasha; Ladanyi, Marc; Ganji, Gopinath 分享 收藏
Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia Ojamies, Pn; Kontro, M.; Edgren, H.; Ellonen, P.; Lagstrom, S.; Almusa, H.; Miettinen, T.; Eldfors, S.; Tamborero, D.; Wennerberg, K.; Heckman, C.; Porkka, K.; Wolf, M.; Kallioniemi, O. 分享 收藏
Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia Eldfors, S.; Kuusanmaki, H.; Kontro, M.; Majumder, M. M.; Parsons, A.; Edgren, H.; Pemovska, T.; Kallioniemi, O.; Wennerberg, K.; Gokbuget, N.; Burmeister, T.; Porkka, K.; Heckman, C. A. 分享 收藏
Responses of AML patients to tailored drug regimens: monitoring cancer subclones by ultra-deep resequencing Ojamies, Poojitha N.; Kontro, Mika; Edgren, Henrik; Ellonen, Pekka; Lagstrom, Sonja; Almusa, Henrikki; Miettinen, Timo; Eldfors, Samuli; Tamborero, David; Wennerberg, Krister; Heckman, Caroline; Porkka, Kimmo; Wolf, Maija; Kallioniemi, Olli 分享 收藏
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Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia Eldfors, S.; Kuusanmaki, H.; Kontro, M.; Majumder, M. M.; Parsons, A.; Edgren, H.; Pemovska, T.; Kallioniemi, O.; Wennerberg, K.; Goekbuget, N.; Burmeister, T.; Porkka, K.; Heckman, C. 分享 收藏
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Suppression of Early Hematogenous Dissemination of Human Breast Cancer Cells to Bone Marrow by Retinoic Acid-Induced 2 Werner, Stefan; Brors, Benedikt; Eick, Julia; Marques, Elsa; Pogenberg, Vivian; Parret, Annabel; Kemming, Dirk; Wood, Antony W.; Edgren, Henrik; Neubauer, Hans; Streichert, Thomas; Riethdorf, Sabine; Bedi, Upasana; Baccelli, Irene; Juecker, Manfred; Eils, Roland; Fehm, Tanja; Trumpp, Andreas; Johnsen, Steven A.; Klefstrom, Juha; Wilmanns, Matthias; Mueller, Volkmar; Pantel, Klaus; Wikman, Harriet 分享 收藏
Analysis of clonal evolution of leukemia in vivo following novel targeted treatments Ojamies, Naga Poojitha; Kontro, Mika; Edgren, Henrik; Eldfors, Samuli; Ellonen, Pekka; Pemovska, Tea; Sonja, Langstrom; Almusa, Henrikki; Lepisto, Maija; Aittokallio, Tero; Wennerberg, Krister; Heckman, Caroline; Porkka, Kimmo; Kallioniemi, Olli 分享 收藏
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Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia Kontro, M.; Kuusanmaki, H.; Eldfors, S.; Burmeister, T.; Andersson, E. I.; Bruserud, O.; Bruemmendorf, T. H.; Edgren, H.; Gjertsen, B. T.; Itala-Remes, M.; Lagstrom, S.; Lohi, O.; Lundan, T.; Marti, J. M. L.; Majumder, M. M.; Parsons, A.; Pemovska, T.; Rajala, H.; Vettenranta, K.; Kallioniemi, O.; Mustjoki, S.; Porkka, K.; Heckman, C. A. 分享 收藏
Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia Pemovska, Tea; Kontro, Mika; Yadav, Bhagwan; Edgren, Henrik; Eldfors, Samuli; Szwajda, Agnieszka; Almusa, Henrikki; Bespalov, Maxim M.; Ellonen, Pekka; Elonen, Erkki; Gjertsen, Bjorn T.; Karjalainen, Riikka; Kulesskiy, Evgeny; Lagstrom, Sonja; Lehto, Anna; Lepisto, Maija; Lundan, Tuija; Majumder, Muntasir Mamun; Marti, Jesus M. Lopez; Mattila, Pirkko; Murumagi, Astrid; Mustjoki, Satu; Palva, Aino; Parsons, Alun; Pirttinen, Tero; Ramet, Maria E.; Suvela, Minna; Turunen, Laura; Vastrik, Imre; Wolf, Maija; Knowles, Jonathan; Aittokallio, Tero; Heckman, Caroline A.; Porkka, Kimmo; Kallioniemi, Olli; Wennerberg, Krister 分享 收藏
Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation Hognas, Gunilla; Hamalisto, Saara; Rilla, Kirsi; Laine, Jukka O.; Vilkki, Vesa; Murumagi, Astrid; Edgren, Henrik; Kallioniemi, Olli; Ivaska, Johanna 分享 收藏
A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon Adenomas Nikolaev, Sergey I.; Sotiriou, Sotirios K.; Pateras, Ioannis S.; Santoni, Federico; Sougioultzis, Stavros; Edgren, Henrik; Almusa, Henrikki; Robyr, Daniel; Guipponi, Michel; Saarela, Janna; Gorgoulis, Vassilis G.; Antonarakis, Stylianos E.; Halazonetis, Thanos D. 分享 收藏
The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells Sahlberg, Kristine Kleivi; Hongisto, Vesa; Edgren, Henrik; Makela, Rami; Hellstrom, Kirsi; Due, Eldri U.; Vollan, Hans Kristian Moen; Sahlberg, Niko; Wolf, Maija; Borresen-Dale, Anne-Lise; Perala, Merja; Kallioniemi, Olli 分享 收藏
The HER2 Amplicon Includes Several Genes Required for the Growth and Survival of HER2 Positive Breast Cancer Cells Hongisto, V.; Sahlberg, K. Kleivi; Edgren, H.; Makela, R.; Due, E.; Vollan, H. K. Moen; Sahlberg, N.; Borresen-Dale, A. L.; Perala, M.; Kallioniemi, O. 分享 收藏
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Exome sequencing reveals both DNA sequence and copy number changes in AML: Potential driver changes and mechanisms of drug resistance revealed from serial samples from the same patients Karjalainen, Riikka; Eldfors, Samuli; Edgren, Henrik; Venkata, Naga Poojitha Kota; Kontro, Mika; Majumder, Muntasir Mamun; Murumagi, Astrid; Parsons, Alun; Almusa, Henrikki; Ellonen, Pekka; Lepisto, Maija; Mattila, Pirkko; Hannula, Sari; Lagstrom, Sonja; Suvela, Minna; Wolf, Maija; Wennerberg, Krister; Knowles, Jonathan K. C.; Mustjoki, Satu; Saarela, Janna; Porkka, Kimmo; Kallioniemi, Olli; Heckman, Caroline A. 分享 收藏
Quantitative drug sensitivity and resistance testing (DSRT) of primary ex vivo AML blasts highlights mTOR and MEK as potential key molecular driver signals of therapeutic significance Pemovska, Tea; Kylesskiy, Evgeny; Kontro, Mika; Szwajda, Agnieszka; Karjalainen, Riikka; Majumder, Muntasir M.; Malani, Disha; Bespalov, Maxim M.; Eldfors, Samuli; Elonen, Erkki; Knowles, Jonathan; Murumagi, Astrid; Mpindi, John P.; Edgren, Henrik; Venkata, Naga Poojitha Kota; Turunen, Laura; Mustjoki, Satu; Wolf, Maija; Yadav, Bhagwan; Aittokallio, Tero; Heckman, Caroline A.; Porkka, Kimmo; Kallioniemi, Olli; Wennerberg, Krister 分享 收藏
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