David A. Horwitz - Publications, H-index & Citations

David A. Horwitz

general nanotherapeutics

62H指数

209论文数

1.3W被引数

收录论文 33

发表时间

CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducing synergistic TGF-β-producing NK cells and Tregs CD2靶向纳米颗粒通过诱导协同产生TGF-β的NK细胞和Tregs，模拟妊娠的母胎耐受。

Frontiers in Immunology

IF5.9

2025-11-24

OAAI

David A. Horwitz; Antonio La Cava

CD2-targeted nanoparticles encapsulating IL-2 induce tolerogenic Tregs and TGF-β-producing NK cells that stabilize Tregs for long-term therapeutic efficacy in immune-mediated disorders 封装IL-2的CD2-targeted纳米颗粒诱导耐受性Tregs和产生tgf-β 的NK细胞，稳定Tregs在免疫介导的疾病中的长期治疗效果

Frontiers in Immunology

IF5.9

2025-07-29

OAAI

David A. Horwitz; Dongin Kim; Chang Kang; Katja Brion; Sean Bickerton; Antonio La Cava

Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-07-26

OAAI

Horwitz, David A.; Wang, Ju Hua; Kim, Dongin; Kang, Chang; Brion, Katja; Bickerton, Sean; Cava, Antonio La

Editorial: Generating and Sustaining Stable Autoantigen-Specific CD4 and CD8 Regulatory T Cells in Lupus

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-03-07

OAAI

Datta, Syamal K.; Horwitz, David A.; Piccirillo, Ciriaco A.; La Cava, Antonio

Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin (vol 5, pg 983, 2021)

NATURE BIOMEDICAL ENGINEERING

IF26.6

2021-11-04

OAAI

Lee, Jung Seok; Han, Patrick; Chaudhury, Rabib; Khan, Shihan; Bickerton, Sean; McHugh, Michael D.; Park, Hyun Bong; Siefert, Alyssa L.; Rea, Gerald; Carballido, Jose M.; Horwitz, David A.; Criscione, Jason; Perica, Karlo; Samstein, Robert; Ragheb, Ragy; Kim, Dongin; Fahmy, Tarek M.

Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin

NATURE BIOMEDICAL ENGINEERING

IF26.6

2021-10-06

PREAI

Strategies to Use Nanoparticles to Generate CD4 and CD8 Regulatory T Cells for the Treatment of SLE and Other Autoimmune Diseases 使用纳米颗粒产生CD4和CD8调节性T细胞治疗SLE和其他自身免疫性疾病的策略

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-06-15

OAAI

Horwitz, David A.; Bickerton, Sean; La Cava, Antonio

Nanoparticles Engineered as Artificial Antigen-Presenting Cells Induce Human CD4+ and CD8+ Tregs That Are Functional in Humanized Mice

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-05-26

OAAI

Giang, Sophia; Horwitz, David A.; Bickerton, Sean; La Cava, Antonio

Anti-CD2 Antibody-Coated Nanoparticles Containing IL-2 Induce NK Cells That Protect Lupus Mice via a TGF-β-Dependent Mechanism

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-12-16

OAAI

Horwitz, David A.; Liu, Aijing; Bickerton, Sean; Castaldo, Giuseppe; Matarese, Giuseppe; Fahmy, Tarek M.; La Cava, Antonio

Rebalancing Immune Homeostasis to Treat Autoimmune Diseases 重新平衡免疫稳态治疗自身免疫性疾病

TRENDS IN IMMUNOLOGY

IF13.9

2019-10-01

OAAI

Horwitz, David A.; Fahmy, Tarek M.; Piccirillo, Ciriaco A.; La Cava, Antonio

Suppression of Murine Lupus by CD4+and CD8+Treg Cells Induced by T Cell-Targeted Nanoparticles Loaded With Interleukin-2 and Transforming Growth Factor β

ARTHRITIS & RHEUMATOLOGY

IF10.9

2019-03-05

OAAI

Horwitz, David A.; Bickerton, Sean; Koss, Michael; Fahmy, Tarek M.; La Cava, Antonio

Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells

BIOMATERIALS

IF12.9

2015-08-01

118

OAAI

McHugh, Michael D.; Park, Jason; Uhrich, Ross; Gao, Wenda; Horwitz, David A.; Fahmy, Tarek M.

Lack of Coagulopathy After Copperhead Snakebites

ANNALS OF EMERGENCY MEDICINE

IF5

2015-04-01

PREAI

Ali, Anah J.; Horwitz, David A.; Mullins, Michael E.

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-08-06

204

OAAI

Lu, Ling; Lan, Qin; Li, Zhiyuan; Zhou, Xiaohui; Gu, Jian; Li, Qiang; Wang, Julie; Chen, Maogen; Liu, Ya; Shen, Yi; Brand, David D.; Ryffel, Bernhard; Horwitz, David A.; Quismorio, Francisco P.; Liu, Zhongmin; Li, Bin; Olsen, Nancy J.; Zheng, Song Guo

Emergency Department Patients With Diabetes Have Better Glycemic Control When They Have Identifiable Primary Care Providers

ACADEMIC EMERGENCY MEDICINE

IF3.2

2012-05-25

OAAI

Horwitz, David A.; Schwarz, Evan S.; Scott, Mitchell G.; Lewis, Lawrence M.

Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu

JOURNAL OF IMMUNOLOGY

IF3.4

2010-09-01

215

OAAI

Zhou, Xiaohui; Kong, Ning; Wang, Julie; Fan, Huiming; Zou, Hejian; Horwitz, David; Brand, David; Liu, Zhongmin; Zheng, Song Guo

Diabetes Interactive Diary: A New Telemedicine System Enabling Flexible Diet and Insulin Therapy While Improving Quality of Life An open-label, international, multicenter, randomized study

DIABETES CARE

IF16.6

2009-10-06

129

OAAI

Rossi, Maria C. E.; Nicolucci, Antonio; Di Bartolo, Paolo; Bruttomesso, Daniela; Girelli, Angela; Ampudia, Francisco J.; Kerr, David; Ceriello, Antonio; De La Questa Mayor, Carmen; Pellegrini, Fabio; Horwitz, David; Vespasiani, Giacomo

Coagulopathy in Pediatric Copperhead Snakebites

ANNALS OF EMERGENCY MEDICINE

IF5

2009-09-01

PREAI

Anderson, B. W.; Horwitz, D. A.; Mullins, M. E.

Glycemic Control Is Improved in Emergency Department Patients With an Identifiable Primary Care Provider

ANNALS OF EMERGENCY MEDICINE

IF5

2009-09-01

PREAI

Horwitz, D.; Schwarz, E.; Scott, M.; Lewis, L.

Interactive Diary for Diabetes: A Useful and Easy-to-Use New Telemedicine System to Support the Decision-Making Process in Type 1 Diabetes

DIABETES TECHNOLOGY & THERAPEUTICS

IF6.3

2009-01-01

PREAI

Rossi, Maria C. E.; Nicolucci, Antonio; Pellegrini, Fabio; Bruttomesso, Daniela; Di Bartolo, Paolo; Marelli, Giuseppe; Dal Pos, Michela; Galetta, Marianna; Horwitz, David; Vespasiani, Giacomo

研究方向