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Rick Havinga

university medical center groningen

H指数:49

被引数:9,268

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Adult-onset deficiency of β-klotho in the liver reveals a novel role in lipid homeostasis

成年期肝脏β-kloto缺陷揭示其在脂质稳态中的新作用

Molecular Metabolism

IF6.6

2026-09-220

OAAI

Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulation

人源化FXR配体结合域的小鼠在药理FXR刺激下表现出不同的代谢反应

Journal of Lipid Research

IF4.1

2026-06-250

OAAI

Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation

生成和表征具有p.E297G突变的胆盐外排泵缺陷小鼠模型

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

IF0

2025-10-170

PRE

The impact of a humanized bile acid composition on atherosclerosis development in hypercholesterolaemic Cyp2c70 knockout mice

SCIENTIFIC REPORTS

IF3.9

2025-01-150

OAAI

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2024-03-010

OAAI

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition

IF3.9

2023-09-083

OAAI

The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2023-06-014

OAAI

Whey-based diet containing medium chain triglycerides modulates the gut microbiota and protects the intestinal mucosa from chemotherapy while maintaining therapy efficacy

CELL DEATH & DISEASE

IF9.6

2023-05-2310

OAAI

Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-03-011

OAAI

T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

NATURE COMMUNICATIONS

IF15.7

2022-07-0133

OAAI

The hepatocyte IKK:NF-kB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

MOLECULAR METABOLISM

IF6.6

2021-12-0144

OAAI

Antibiotic-induced disruption of the microbiome exacerbates chemotherapy-induced diarrhoea and can be mitigated with autologous faecal microbiota transplantation

EUROPEAN JOURNAL OF CANCER

IF7.1

2021-08-0124

OA

Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

SCIENTIFIC REPORTS

IF3.9

2021-05-2715

OAAI

Effects of an early life diet containing large phospholipid-coated lipid globules on hepatic lipid metabolism in mice

SCIENTIFIC REPORTS

IF3.9

2020-09-3010

OAAI

Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis

IF11

2020-08-2610

OAAI

An early-life diet containing large phospholipid-coated lipid globules programmes later-life postabsorptive lipid trafficking in high-fat diet- but not in low-fat diet-fed mice

BRITISH JOURNAL OF NUTRITION

IF3

2020-07-038

OA

Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

CARDIOVASCULAR RESEARCH

IF13.3

2019-10-0723

OAAI

Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

IF15.8

2019-08-1315

OAAI

LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats

PEDIATRIC RESEARCH

IF3.1

2019-03-098

OAAI

AAV8-mediated gene transfer of microRNA-132 improves beta cell function in mice fed a high-fat diet

JOURNAL OF ENDOCRINOLOGY

IF3.9

2019-02-0112

OA