未登录 Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia 大胞饮作用的适应性刺激克服了缺氧条件下癌细胞的天冬氨酸限制 Garcia-Bermudez, Javier; Badgley, Michael A.; Prasad, Sheela; Baudrier, Lou; Liu, Yuyang; La, Konnor; Soula, Mariluz; Williams, Robert T.; Yamaguchi, Norihiro; Hwang, Rosa F.; Taylor, Laura J.; de Stanchina, Elisa; Rostandy, Bety; Alwaseem, Hanan; Molina, Henrik; Bar-Sagi, Dafna; Birsoy, Kivanc 分享 收藏
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Dietary thiamine influences L-asparaginase sensitivity in a subset of leukemia cells Guarecuco, Rohiverth; Williams, Robert T.; Baudrier, Lou; La, Konnor; Passarelli, Maria C.; Ekizoglu, Naz; Mestanoglu, Mert; Alwaseem, Hanan; Rostandy, Bety; Fidelin, Justine; Garcia-Bermudez, Javier; Molina, Henrik; Birsoy, Kivanc 分享 收藏
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers 癌细胞对典型铁死亡诱导剂敏感性的代谢决定因素 Soula, Mariluz; Weber, Ross A.; Zilka, Omkar; Alwaseem, Hanan; La, Konnor; Yen, Frederick; Molina, Henrik; Garcia-Bermudez, Javier; Pratt, Derek A.; Birsoy, Kivanc 分享 收藏
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism Bayraktar, Erol C.; La, Konnor; Karpman, Kara; Unlu, Gokhan; Ozerdem, Ceren; Ritter, Dylan J.; Alwaseem, Hanan; Molina, Henrik; Hoffmann, Hans-Heinrich; Millner, Alec; Atilla-Gokcumen, G. Ekin; Gamazon, Eric R.; Rushing, Amy R.; Knapik, Ela W.; Basu, Sumanta; Birsoy, Kivanc 分享 收藏
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase Williams, Robert T.; Guarecuco, Rohiverth; Gates, Leah A.; Barrows, Douglas; Passarelli, Maria C.; Carey, Bryce; Baudrier, Lou; Jeewajee, Swarna; La, Konnor; Prizer, Benjamin; Malik, Sohail; Garcia-Bermudez, Javier; Zhu, Xiphias Ge; Cantor, Jason; Molina, Henrik; Carroll, Thomas; Roeder, Robert G.; Abdel-Wahab, Omar; Allis, C. David; Birsoy, Kivanc 分享 收藏
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation Weber, Ross A.; Yen, Frederick S.; Nicholson, Shirony P., V; Alwaseem, Hanan; Bayraktar, Erol C.; Alam, Mohammad; Timson, Rebecca C.; La, Konnor; Abu-Remaileh, Monther; Molina, Henrik; Birsoy, Kivanc 分享 收藏
CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4 Zhu, Xiphias Ge; Puthenveedu, Shirony Nicholson; Shen, Yihui; La, Konnor; Ozlu, Can; Wang, Tim; Klompstra, Diana; Gultekin, Yetis; Chi, Jingyi; Fidelin, Justine; Peng, Tao; Molina, Henrik; Hang, Howard C.; Min, Wei; Birsoy, Kivanc 分享 收藏
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours (vol 20, pg 775, 2018) Garcia-Bermudez, Javier; Baudrier, Lou; La, Konnor; Zhu, Xiphias Ge; Fidelin, Justine; Sviderskiy, Vladislav O.; Papagiannakopoulos, Thales; Molina, Henrik; Snuderl, Matija; Lewis, Caroline A.; Possemato, Richard L.; Birsoy, Kivanc 分享 收藏
Multiple mutations to the same gene are selected for and cooperate to drive cancer Gorelick, Alexander N.; Reznik, Ed; Cai, Yanyan; Bielski, Craig; Bandlamudi, Chaitanya; Penson, Alexander; Jonsson, Philip; La, Konnor; Scaltriti, Maurizio; Schultz, Nikolaus; Taylor, Barry S. 分享 收藏
The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas Sanchez-Vega, Francisco; Mina, Marco; Armenia, Joshua; Chatila, Walid K.; Luna, Augustin; La, Konnor; Dimitriadoy, Sofia; Liu, David L.; Kantheti, Havish S.; Heins, Zachary; Ochoa, Angelica; Gross, Benjamin; Gao, Jianjiong; Zhang, Hongxin; Kundra, Ritika; Kandoth, Cyriac; Bahceci, Istemi; Dervishi, Leonard; Dogrusoz, Ugur; Zhou, Wanding; Shen, Hui; Laird, Peter W.; Berger, Alice H.; Bivona, Trever G.; Lazar, Alexander J.; Hammer, Gary; Giordano, Thomas; Kwong, Lawrence; McArthur, Grant; Huang, Chenfei; Frederick, Mitchell J.; McCormick, Frank; Meyerson, Matthew; Van Allen, Eliezer; Cherniack, Andrew D.; Ciriello, Giovanni; Sander, Chris; Schultz, Nikolaus 分享 收藏
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours Garcia-Bermudez, Javier; Baudrier, Lou; La, Konnor; Zhu, Xiphias Ge; Fidelin, Justine; Sviderskiy, Vladislav O.; Papagiannakopoulos, Thales; Molina, Henrik; Snuderl, Matija; Lewis, Caroline A.; Possemato, Richard L.; Birsoy, Kivanc 分享 收藏
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Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene Montero-Conde, Cristina; Leandro-Garcia, Luis J.; Chen, Xu; Oler, Gisele; Ruiz-Llorente, Sergio; Ryder, Mabel; Landa, Inigo; Sanchez-Vega, Francisco; La, Konnor; Ghossein, Ronald A.; Bajorin, Dean F.; Knauf, Jeffrey A.; Riordan, Jesse D.; Dupuy, Adam J.; Fagin, James A. 分享 收藏
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