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收藏A cytosolic mutp53(E285K) variant confers chemoresistance of malignant melanoma
Dunsche, Luise; Ivanisenko, Nikita; Riemann, Shamala; Schindler, Sebastian; Beissert, Stefan; Angeli, Cristian; Kreis, Stephanie; Tavassoli, Mahvash; Lavrik, Inna; Kulms, Dagmar 分享 收藏 Inhibition of extracellular vesicle-derived miR-146a-5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes抑制细胞外囊泡来源的miR-146a-5p通过星形胶质细胞Notch通路失调减少黑色素瘤脑转移的进展Rigg, Emma; Wang, Jiwei; Xue, Zhiwei; Lunavat, Taral R.; Liu, Guowei; Hoang, Tuyen; Parajuli, Himalaya; Han, Mingzhi; Bjerkvig, Rolf; Nazarov, Petr V.; Nicot, Nathalie; Kreis, Stephanie; Margue, Christiane; Nomigni, Milene Tetsi; Utikal, Jochen; Miletic, Hrvoje; Sundstrom, Terje; Ystaas, Lars A. R.; Li, Xingang; Thorsen, Frits 分享 收藏 Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanomaBintener, Tamara; Pacheco, Maria Pires; Philippidou, Demetra; Margue, Christiane; Kishk, Ali; Del Mistro, Greta; Di Leo, Luca; Moscardo Garcia, Maria; Halder, Rashi; Sinkkonen, Lasse; De Zio, Daniela; Kreis, Stephanie; Kulms, Dagmar; Sauter, Thomas 分享 收藏 A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma多组学整合方法阐明了NRAS突变型黑色素瘤靶向治疗后与衰老逃逸相关的新基因和途径Gureghian, Vincent; Herbst, Hailee; Kozar, Ines; Mihajlovic, Katarina; Malod-Dognin, Noel; Ceddia, Gaia; Angeli, Cristian; Margue, Christiane; Randic, Tijana; Philippidou, Demetra; Nomigni, Milene Tetsi; Hemedan, Ahmed; Tranchevent, Leon-Charles; Longworth, Joseph; Bauer, Mark; Badkas, Apurva; Gaigneaux, Anthoula; Muller, Arnaud; Ostaszewski, Marek; Tolle, Fabrice; Przulj, Natasa; Kreis, Stephanie 分享 收藏 Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug responseRandic, Tijana; Magni, Stefano; Philippidou, Demetra; Margue, Christiane; Grzyb, Kamil; Preis, Jasmin Renate; Wroblewska, Joanna Patrycja; Nazarov, Petr V.; Mittelbronn, Michel; Frauenknecht, Katrin B. M.; Skupin, Alexander; Kreis, Stephanie 分享 收藏 分享 收藏 A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cellsCesi, Giulia; Philippidou, Demetra; Kozar, Ines; Kim, Yeoun Jin; Bernardin, Francois; Van Niel, Guillaume; Wienecke-Baldacchino, Anke; Felten, Paul; Letellier, Elisabeth; Dengler, Sonja; Nashan, Dorothee; Haan, Claude; Kreis, Stephanie 分享 收藏 Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancerBauer, Andrea S.; Nazarov, Petr V.; Giese, Nathalia A.; Beghelli, Stefania; Heller, Anette; Greenhalf, William; Costello, Eithne; Muller, Arnaud; Bier, Melanie; Strobel, Oliver; Hackert, Thilo; Vallar, Laurent; Scarpa, Aldo; Buechler, Markus W.; Neoptolemos, John P.; Kreis, Stephanie; Hoheisel, Joerg D. 分享 收藏 
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