未登录 分享 收藏
分享 收藏
Safety, tolerability, pharmacokinetics and pharmacodynamics after repeated once or twice daily R-1201, a TPH inhibitor for treatment of PAH Wring, Stephen; Rurka, Julie; Crizer, Katelyn; Palacios, Michelle; Snyder, Michele; Keller, Laurence; Evans, Philip; Carpenter, David 分享 收藏
分享 收藏
MSG-10: a Phase 2 study of oral ibrexafungerp (SCY-078) following initial echinocandin therapy in non-neutropenic patients with invasive candidiasis Spec, Andrej; Pullman, John; Thompson, George R., III; Powderly, William G.; Tobin, Ellis H.; Vazquez, Jose; Wring, Stephen A.; Angulo, David; Helou, Silvia; Pappas, Peter G.; Ostrosky-Zeichner, Luis; Patterson, Thomas; Alexander, Barbara; Boucher, Helen; Pappas, Peter; Betts, Robert; Schuster, Mindy; Shoham, Shmuel; Revankar, Sanjay; Mushatt, David; Bedimo, Roger; Freifeld, Alison; Nguyen, Minh Hong; Mylonakis, Eleftherios; Kett, Daniel; Reboli, Annette; Walsh, Thomas; Pouch, Stephanie; Almyroudis, Nikolaos; Andes, David; Hadley, Susan; Barron, Michelle; Mullane, Katheen; Miller, Loren 分享 收藏
分享 收藏
The pro-inflammatory immunophenotype of a Farber disease mouse model is ameliorated by repeated dosing with RVT-801, a developmental enzyme replacement therapy for Farber disease Sampey, Brante P.; Duke, Katie S.; Sampey, Gavin C.; Gaukel, Eric J.; Solyom, Alexander; Wring, Stephen A.; He, Xingxuan; Zhu, Changzhi; DeAngelis, Victor; Schuchman, Edward H.; Coquery, Christine M. 分享 收藏
Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles 皮肤利什曼病的局部治疗: 苯并氧杂硼的皮肤药代动力学铅优化 Van Bocxlaer, Katrien; Gaukel, Eric; Hauser, Deirdre; Park, Seong Hee; Schock, Sara; Yardley, Vanessa; Randolph, Ryan; Plattner, Jacob J.; Merchant, Tejal; Croft, Simon L.; Jacobs, Robert T.; Wring, Stephen A. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity Brockway, Anthony J.; Volkov, Oleg A.; Cosner, Casey C.; MacMillan, Karen S.; Wring, Stephen A.; Richardson, Thomas E.; Peel, Michael; Phillips, Margaret A.; De Brabander, Jef K. 分享 收藏
Identification of Trypanosoma brucei AdoMetDC Inhibitors Using a High-Throughput Mass Spectrometry-Based Assay Volkov, Oleg A.; Cosner, Casey C.; Brockway, Anthony J.; Kramer, Martin; Booker, Michael; Zhong, Shihua; Ketcherside, Ariel; Wei, Shuguang; Longgood, Jamie; McCoy, Melissa; Richardson, Thomas E.; Wring, Stephen A.; Peel, Michael; Klinger, Jeffrey D.; Posner, Bruce A.; De Brabander, Jef K.; Phillips, Margaret A. 分享 收藏
Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis Wring, Stephen A.; Randolph, Ryan; Park, SeongHee; Abruzzo, George; Chen, Qing; Flattery, Amy; Garrett, Graig; Peel, Michael; Outcalt, Russell; Powell, Kendall; Trucksis, Michelle; Angulo, David; Borroto-Esoda, Katyna 分享 收藏
分享 收藏
Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis Jacobs, Robert T.; Plattner, Jacob J.; Nare, Bakela; Wring, Stephen A.; Chen, Daitao; Freund, Yvonne; Gaukel, Eric G.; Orr, Matthew D.; Perales, Joe B.; Jenks, Matthew; Noe, Robert A.; Sligar, Jessica M.; Zhang, Yong-Kang; Bacchi, Cyrus J.; Yarlett, Nigel; Don, Robert 分享 收藏
SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis Jacobs, Robert T.; Nare, Bakela; Wring, Stephen A.; Orr, Matthew D.; Chen, Daitao; Sligar, Jessica M.; Jenks, Matthew X.; Noe, Robert A.; Bowling, Tana S.; Mercer, Luke T.; Rewerts, Cindy; Gaukel, Eric; Owens, Jennifer; Parham, Robin; Randolph, Ryan; Beaudet, Beth; Bacchi, Cyrus J.; Yarlett, Nigel; Plattner, Jacob J.; Freund, Yvonne; Ding, Charles; Akama, Tsutomu; Zhang, Y. -K.; Brun, Reto; Kaiser, Marcel; Scandale, Ivan; Don, Robert 分享 收藏
Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis Nare, Bakela; Wring, Stephen; Bacchi, Cyrus; Beaudet, Beth; Bowling, Tana; Brun, Reto; Chen, Daitao; Ding, Charles; Freund, Yvonne; Gaukel, Eric; Hussain, Ali; Jarnagin, Kurt; Jenks, Matthew; Kaiser, Marcel; Mercer, Luke; Mejia, Elena; Noe, Andy; Orr, Matt; Parham, Robin; Plattner, Jacob; Randolph, Ryan; Rattendi, Donna; Rewerts, Cindy; Sligar, Jessica; Yarlett, Nigel; Don, Robert; Jacobs, Robert 分享 收藏
SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA Replication In Vitro Hopkins, Sam; Scorneaux, Bernard; Huang, Zhuhui; Murray, Michael G.; Wring, Stephen; Smitley, Craig; Harris, Richard; Erdmann, Frank; Fischer, Gunter; Ribeill, Yves 分享 收藏
SAFETY, PLASMA PHARMACOKINETICS, AND ANTI-VIRAL ACTIVITY OF SCY-635 IN ADULT PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION Hopkins, S.; Heuman, D.; Gavis, E.; Lalezari, J.; Glutzer, E.; DiMassimo, B.; Rusnak, P.; Wring, S.; Smitley, C.; Ribeill, Y. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
