Hiroshi Kiwada - Publications, H-index & Citations

Hiroshi Kiwada

tokushima university

56H指数

306论文数

1.2W被引数

收录论文 83

发表时间

Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose

JOURNAL OF CONTROLLED RELEASE

IF11.5

2015-12-01

PREAI

Nakamura, Hiroyuki; Abu Lila, Amr S.; Nishio, Miho; Tanaka, Masao; Ando, Hidenori; Kiwada, Hiroshi; Ishida, Tatsuhiro

Comprehensive analysis of PEGylated liposome-associated proteins relating to the accelerated blood clearance phenomenon by combination with shotgun analysis and conventional methods

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2014-12-24

PREAI

Kawanishi, Munehira; Hashimoto, Yosuke; Shimizu, Taro; Sagawa, Ikuko; Ishida, Tatsuhiro; Kiwada, Hiroshi

Influence of dose and animal species on accelerated blood clearance of PEGylated liposomal doxorubicin 剂量和动物种类对聚乙二醇化脂质体阿霉素加速血液清除率的影响

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2014-12-01

PREAI

Suzuki, Takuya; Ichihara, Masako; Hyodo, Kenji; Yamamoto, Eiichi; Ishida, Tatsuhiro; Kiwada, Hiroshi; Kikuchi, Hiroshi; Ishihara, Hiroshi

B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice

JOURNAL OF CONTROLLED RELEASE

IF11.5

2014-06-01

PREAI

Hashimoto, Yosuke; Abu Lila, Amr S.; Shimizu, Taro; Ishida, Tatsuhiro; Kiwada, Hiroshi

Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2014-05-01

PREAI

Hashimoto, Yosuke; Shimizu, Taro; Mima, Yu; Abu Lila, Amr S.; Ishida, Tatsuhiro; Kiwada, Hiroshi

Application of Polyglycerol Coating to Plasmid DNA Lipoplex for the Evasion of the Accelerated Blood Clearance Phenomenon in Nucleic Acid Delivery

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2014-02-01

PREAI

Abu Lila, Amr S.; Uehara, Yumi; Ishida, Tatsuhiro; Kiwada, Hiroshi

The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage

JOURNAL OF CONTROLLED RELEASE

IF11.5

2013-11-01

552

PREAI

Abu Lila, Amr S.; Kiwada, Hiroshi; Ishida, Tatsuhiro

Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2013-11-01

110

PREAI

Abu Lila, Amr S.; Nawata, Kosuke; Shimizu, Taro; Ishida, Tatsuhiro; Kiwada, Hiroshi

The Co-Delivery of Oxaliplatin Abrogates the Immunogenic Response to PEGylated siRNA-Lipoplex

PHARMACEUTICAL RESEARCH

IF4.3

2013-05-15

PREAI

Alaaeldin, Eman; Abu Lila, Amr S.; Moriyoshi, Naoto; Sarhan, Hatem A.; Ishida, Tatsuhiro; Khaled, Khaled A.; Kiwada, Hiroshi

Suppression of immune response by antigen-modified liposomes encapsulating model agents: A novel strategy for the treatment of allergy

JOURNAL OF CONTROLLED RELEASE

IF11.5

2013-05-01

PREAI

Ichikawa, Kanae; Asai, Tomohiro; Shimizu, Kosuke; Yonezawa, Sei; Urakami, Takeo; Miyauchi, Haruna; Kawashima, Hiroto; Ishida, Tatsuhiro; Kiwada, Hiroshi; Oku, Naoto

Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: Promise for clinical application

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2013-01-01

PREAI

Nagao, Ai; Abu Lila, Amr S.; Ishida, Tatsuhiro; Kiwada, Hiroshi

Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: A possible mechanism and the potential for clinical application

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2012-11-01

PREAI

Abu Lila, Amr S.; Eldin, Noha Essam; Ichihara, Masako; Ishida, Tatsuhiro; Kiwada, Hiroshi

An Entirely Novel Nanoparticle Carrying a Bioactive shRNA Molecule (DFP-10825) Could Be Clinically Effective Against the High Risk Patients with Mesothelioma Relapsed or Refractory After Treatment with Pemetrexed Based Chemotherapy

EUROPEAN JOURNAL OF CANCER

IF7.1

2012-11-01

PREAI

Ishida, T.; Abu Lila, A. S.; Huang, C.; Wada, H.; Fukushima, M.; Kiwada, H.

Accelerated blood clearance of PEGylated liposomes containing doxorubicin upon repeated administration to dogs 重复给予狗后，含有阿霉素的聚乙二醇化脂质体的血液清除率加快

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2012-10-01

115

PREAI

Suzuki, Takuya; Ichihara, Masako; Hyodo, Kenji; Yamamoto, Eiichi; Ishida, Tatsuhiro; Kiwada, Hiroshi; Ishihara, Hiroshi; Kikuchi, Hiroshi

Agitation during lipoplex formation harmonizes the interaction of siRNA to cationic liposomes

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2012-07-01

PREAI

Barichello, Jose Mario; Kizuki, Shinji; Tagami, Tatsuaki; Lira Soares, Luiz Alberto; Ishida, Tatsuhiro; Kikuchi, Hiroshi; Kiwada, Hiroshi

Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: Synergy or antagonism?

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2012-04-01

PREAI

Abu Lila, Amr S.; Okada, Tomoko; Doi, Yusuke; Ichihara, Masako; Ishida, Tatsuhiro; Kiwada, Hiroshi

Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

DRUG DELIVERY AND TRANSLATIONAL RESEARCH

IF5.5

2012-01-19

PREAI

Tagami, Tatsuaki; Abu Lila, Amr S.; Matsunaga, Mariko; Moriyoshi, Naoto; Nakamura, Hiroyuki; Nakamura, Kazuya; Suzuki, Takuya; Doi, Yusuke; Ishida, Tatsuhiro; Kiwada, Hiroshi

Anti-angiogenic therapy via cationic liposome-mediated systemic siRNA delivery

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2012-01-01

PREAI

Tagami, Tatsuaki; Suzuki, Takuya; Matsunaga, Mariko; Nakamura, Kazuya; Moriyoshi, Naoto; Ishida, Tatsuhiro; Kiwada, Hiroshi

A Double-modulation Strategy in Cancer Treatment With a Chemotherapeutic Agent and siRNA

MOLECULAR THERAPY

IF12

2011-11-01