未登录Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1
Tardif, Keith D.; Rogers, Aaron; Cassiano, Jared; Roth, Bruce L.; Cimbora, Daniel M.; McKinnon, Rena; Peterson, Ashley; Douce, Thomas B.; Robinson, Rosann; Dorweiler, Irene; Davis, Thaylon; Hess, Mark A.; Ostanin, Kirill; Papac, Damon I.; Baichwal, Vijay; McAlexander, Ian; Willardsen, J. Adam; Saunders, Michael; Christophe, Hoarau; Kumar, D. Vijay; Wettstein, Daniel A.; Carlson, Robert O.; Williams, Brandi L.
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收藏Discovery and SAR of Methylated Tetrahydropyranyl Derivatives as Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase (ICMT)甲基化四氢吡喃衍生物作为异戊二烯基半胱氨酸羧基甲基转移酶 (ICMT) 抑制剂的发现和SAR
Judd, Weston R.; Slattum, Paul M.; Hoang, Khanh C.; Bhoite, Leena; Valppu, Liisa; Alberts, Glen; Brown, Brita; Roth, Bruce; Ostanin, Kirill; Huang, Liwen; Wettstein, Daniel; Richards, Burt; Willardsen, J. Adam
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收藏Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as Potent Inhibitors of Nicotinamide Phosphoribosyltransferase (Nampt)
Lockman, Jeffrey W.; Murphy, Brett R.; Zigar, Daniel F.; Judd, Weston R.; Slattum, Paul M.; Gao, Zhong-Hua; Ostanin, Kirill; Green, Jeremy; McKinnon, Rena; Terry-Lorenzo, Ryan T.; Fleischer, Tracey C.; Boniface, J. Jay; Shenderovich, Mark; Willardsen, J. Adam
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收藏Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration
Sirisoma, Nilantha; Pervin, Azra; Zhang, Hong; Jiang, Songchun; Willardsen, J. Adam; Anderson, Mark B.; Mather, Gary; Pleiman, Christopher M.; Kasibhatla, Shailaja; Tseng, Ben; Drewe, John; Cai, Sui Xiong
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收藏Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity
Sirisoma, Nilantha; Kasibhatla, Shailaja; Pervin, Azra; Zhang, Hong; Jiang, Songchun; Willardsen, J. Adam; Anderson, Mark B.; Baichwal, Vijay; Mather, Gary G.; Jessing, Kevin; Hussain, Raouf; Hoang, Khanh; Pleiman, Christopher M.; Tseng, Ben; Drewe, John; Cai, Sui Xiong
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收藏Protease-activated receptor 2, dipeptidyl peptidase 1, and proteases mediate Clostridium difficile toxin A enteritis
Cottrell, Graeme S.; Amadesi, Silvia; Pikios, Stella; Camerer, Eric; Willardsen, J. Adam; Murphy, Brett R.; Caughey, George H.; Wolters, Paul J.; Coughlin, Shaun R.; Peterson, Anders; Knecht, Wolfgang; Pothoulakis, Charalabos; Bunnett, Nigel W.; Grady, Eileen F.
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收藏Design, synthesis, and biological activity of potent and selective inhibitors of blood coagulation factor Xa
Willardsen, JA; Dudley, DA; Cody, WL; Chi, LG; McClanahan, TB; Mertz, TE; Potoczak, RE; Narasimhan, LS; Holland, DR; Rapundalo, ST; Edmunds, JJ
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