Harald Tschesche - Publications, H-index & Citations

Harald Tschesche

leiden university medical center (lumc)

55H指数

404论文数

1.1W被引数

收录论文 26

发表时间

Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2007-08-01

141

PREAI

Kubben, Frank J. G. M.; Sier, Cornelis F. M.; Hawinkels, Lukas J. A. C.; Tschesche, Harald; van Duijn, Wim; Zuidwijk, Kim; van der Reijden, Johan J.; Hanemaaijer, Roeland; Griffioen, Gerrit; Lamers, Cornelis B. H. W.; Verspaget, Hein W.

HIGH MMP-9/NGAL COMPLEX LEVELS IN GASTRIC CANCER TISSUE ARE ASSOCIATED WITH WORSE SURVIVAL

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2006-10-01

PREAI

Sier, C.; Kubben, F.; Hawinkels, L.; Tschesche, H.; van Duijn, W.; Zuidwijk, K.; van der Reijden, J.; Hanemaaijer, R.; Griffioen, G.; Verspaget, H.

Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-01-17

PREAI

Pochetti, G; Gavuzzo, E; Campestre, C; Agamennone, M; Tortorella, P; Consalvi, V; Gallina, C; Hiller, O; Tschesche, H; Tucker, PA; Mazza, F

Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients 牙周炎患者龈沟液和唾液中的基质金属蛋白酶及其抑制剂

JOURNAL OF CLINICAL PERIODONTOLOGY

IF6.8

2005-12-13

271

PREAI

Ingman, T; Tervahartiala, T; Ding, YL; Tschesche, H; Haerian, A; Kinane, DF; Konttinen, YT; Sorsa, T

ADAM15 decreases integrin αvβ3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2005-03-01

PREAI

Beck, V; Herold, H; Benge, A; Luber, B; Hutzler, P; Tschesche, H; Kessler, H; Schmitt, M; Geppert, HG; Reuning, U

Evidence for disulfide involvement in the regulation of intramolecular autolytic processing by human adamalysin19/ADAM19

EXPERIMENTAL CELL RESEARCH

IF3.5

2004-08-01

PREAI

Kang, TB; Tschesche, H; Sang, QXA

Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities

BIOCHEMICAL JOURNAL

IF4.3

2004-02-01

OAAI

Hurst, DR; Schwartz, MA; Ghaffari, MA; Jin, YH; Tschesche, H; Fields, GB; Sang, QXA

Autolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2002-12-01

OAAI

Kang, TB; Park, HI; Suh, Y; Zhao, YG; Tschesche, H; Sang, QXA

Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I - Role of the activation cleavage and of the hemopexin-like domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2002-06-01

OAAI

Gioia, M; Fasciglione, GF; Marini, S; D'Alessio, S; De Sanctis, G; Diekmann, O; Pieper, M; Politi, V; Tschesche, H; Coletta, M

Computational study of the catalytic domain of human neutrophil collagenase.: Specific role of the S3 and S′3 subsites in the interaction with a phosphonate inhibitor

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2002-01-01

PREAI

Aschi, M; Roccatano, D; Di Nola, A; Gallina, C; Gavuzzo, E; Pochetti, G; Pieper, M; Tschesche, H; Mazza, F

MMP-TIMP interaction depends on residue 2 in TIMP-4

FEBS LETTERS

IF3

2001-11-02

OAAI

Stratmann, B; Farr, M; Tschesche, H

Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2001-08-31

PREAI

Schröder, J; Henke, A; Wenzel, H; Brandstetter, H; Stammler, HG; Stammler, A; Pfeiffer, WD; Tschesche, H

Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (membrane type 1)-MMP-dependent activation of pro-MMP-2

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2000-12-01

122

OAAI

Toth, M; Bernardo, MM; Gervasi, DC; Soloway, PD; Wang, ZP; Bigg, HF; Overall, CM; DeClerck, YA; Tschesche, H; Cher, ML; Brown, S; Mobashery, S; Fridman, R

Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: Implications for drug design

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2000-08-12

PREAI

Gavuzzo, E; Pochetti, G; Mazza, F; Gallina, C; Gorini, B; D'Alessio, S; Pieper, M; Tschesche, H; Tucker, PA

Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1999-09-01

PREAI

Wilharm, E; Parry, MAA; Friebel, R; Tschesche, H; Matschiner, G; Sommerhoff, CP; Jenne, DE

Collagenolysis in the lower uterine segment during parturition at term: Correlations with stage of cervical dilatation and duration of labor

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

IF8.4

1999-07-01

PREAI

Winkler, M; Oberpichler, A; Tschesche, H; Ruck, P; Fischer, DC; Rath, W

Design and synthesis of heterotrimeric collagen peptides with a built-in cystine-knot - Models for collagen catabolism by matrix-metalloproteases

FEBS LETTERS

IF3

1999-03-19

103

OAAI

Ottl, J; Battistuta, R; Pieper, M; Tschesche, H; Bode, W; Kuhn, K; Moroder, L

Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites -: Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan

BIOCHEMICAL JOURNAL

IF4.3

1998-07-01

OAAI

Büttner, FH; Hughes, CE; Margerie, D; Lichte, A; Tschesche, H; Caterson, B; Bartnik, E

Contribution of matrix metalloproteinases to colorectal cancer invasion and metastasis.

GASTROENTEROLOGY

IF25.1

1998-04-01

OAAI

Kubben, FJGM; van Duijn, W; Mieremet-Ooms, MAC; Janssen, AML; Süwer, V; Oberpichler, A; Tschesche, H; Verheijen, JH; Hanemaaijer, R; Griffioen, G; Lamers, CBHW; Verspaget, HW

Potentiative effects of neutral proteinases in an inflamed lung: Relationship of neutrophil procollagenase (proMMP-8) to plasmin, cathepsin G and tryptase in bronchiectasis in vivo

EUROPEAN RESPIRATORY JOURNAL

IF21

1997-12-01

OAAI

Sepper, R; Konttinen, YT; Buo, L; Eklund, KK; Lauhio, A; Sorsa, T; Tschesche, H; Aasen, AO; Sillastu, H

研究方向