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J

Jordan T.F. Young

University of Toronto
H指数:15
被引数:2,033

个人简介

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教育背景

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工作经历

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荣誉奖项

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Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations

全基因组CRISPR筛选绘制复发性癌症驱动基因改变中的合成致死相互作用

Cell Reports
IF6.9
2026-09-010
PRE
Desjardins, Jessica; Bowlan, Julian; Bernier, Cynthia; Jain, Srishti; de Rugy, Theo Goullet; Gallo, David; Orcholski, Mark E.; Laterreur, Nancy; Rajah, Abira; Miller, Joshua; Lafontaine, Jennifer; Bhaskaran, Vivek; Li, Li; Ling, Alexanda; Leblanc, Jesse H.; Mathieu, Marie-Claude; Zinda, Michael; Morris, Stephen J.; Durocher, Daniel; Zimmermann, Michal; Roulston, Anne; Veloso, Artur; Fiore, Chris; Alvarez-Quilon, Alejandro; Young, Jordan T. F.
Guiding ATR and PARP inhibitor combinations with chemogenomic screens

用化学基因组学筛选指导ATR和PARP抑制剂组合

CELL REPORTS
IF6.9
2022-07-0126
OA
Zimmermann, Michal; Bernier, Cynthia; Kaiser, Beatrice; Fournier, Sara; Li, Li; Desjardins, Jessica; Skeldon, Alexander; Rimkunas, Victoria; Veloso, Artur; Young, Jordan T. F.; Roulston, Anne; Zinda, Michael; Desjardins, Jessica; Skeldon, Alexander; Rimkunas, Victoria; Veloso, Artur; Young, Jordan T. F.; Roulston, Anne; Zinda, Michael
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-12-1557
OAAI
Roulston, Anne; Zimmermann, Michal; Papp, Robert; Skeldon, Alexander; Pellerin, Charles; Dumas-Berube, Emilie; Dumais, Valerie; Dorich, Stephane; Fader, Lee D.; Fournier, Sara; Li, Li; Leclaire, Marie-Eve; Yin, Shou Yun; Chefson, Amandine; Alam, Hunain; Yang, William; Fugere-Desjardins, Chloe; Vignini-Hammond, Sabrina; Skorey, Kathryn; Mulani, Amina; Rimkunas, Victoria; Veloso, Artur; Hamel, Martine; Stocco, Rino; Mamane, Yael; Li, Zuomei; Young, Jordan T. F.; Zinda, Michael; Black, W. Cameron
RP-3500: A novel, potent and selective ATR inhibitor that is effective in pre-clinical models as a monotherapy and in combination with PARP inhibitors
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-12-010
PRE
Roulston, Anne; Zimmerman, Michal; Papp, Robert; Skeldon, Alex; Pellerin, Charles; Dumas-Berube, Emilie; Dumais, Valerie; Dorich, Stephane; Fournier, Sara; Li, Li; Leclaire, Marie-Eve; Yin, Shou Yun; Chefson, Amandine; Alam, Hunain; Yang, William; Fugere-Desjardins, Chloe; Hammond, Sabrina; Skorey, Kathryn; Mulani, Amina; Rimkunas, Victoria; Veloso, Artur; Hamel, Martine; Stocco, Rino; Mamane, Yael; Li, Zuomei; Young, Jordan; Zinda, Mike; Black, Cameron
The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer
NATURE CANCER
IF28.5
2021-11-1154
PRE
Adam, Salome; Rossi, Silvia Emma; Moatti, Nathalie; Zompit, Mara De Marco; Xue, Yibo; Ng, Timothy F.; Alvarez-Quilon, Alejandro; Desjardins, Jessica; Bhaskaran, Vivek; Martino, Giovanni; Setiaputra, Dheva; Noordermeer, Sylvie M.; Ohsumi, Toshiro K.; Hustedt, Nicole; Szilard, Rachel K.; Chaudhary, Natasha; Munro, Meagan; Veloso, Artur; Melo, Henrique; Yin, Shou Yun; Papp, Robert; Young, Jordan T. F.; Zinda, Michael; Stucki, Manuel; Durocher, Daniel
Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease
MOLECULAR CELL
IF16.6
2020-06-0180
OAAI
Alvarez-Quilon, Alejandro; Wojtaszek, Jessica L.; Mathieu, Marie-Claude; Patel, Tejas; Appel, C. Denise; Hustedt, Nicole; Rossi, Silvia Emma; Wallace, Bret D.; Setiaputra, Dheva; Adam, Salome; Ohashi, Yota; Melo, Henrique; Cho, Tiffany; Gervais, Christian; Munoz, Ivan M.; Grazzini, Eric; Young, Jordan T. F.; Rouse, John; Zinda, Michael; Williams, R. Scott; Durocher, Daniel
HELB Is a Feedback Inhibitor of DNA End Resection
MOLECULAR CELL
IF16.6
2016-02-01125
OA
Tkac, Jan; Xu, Guotai; Adhikary, Hemanta; Young, Jordan T. F.; Gallo, David; Escribano-Diaz, Cristina; Krietsch, Jana; Orthwein, Alexandre; Munro, Meagan; Sol, Wendy; Al-Hakim, Abdallah; Lin, Zhen-Yuan; Jonkers, Jos; Borst, Piet; Brown, Grant W.; Gingras, Anne-Claude; Rottenberg, Sven; Masson, Jean-Yves; Durocher, Daniel
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
MOLECULAR SYSTEMS BIOLOGY
IF7.7
2013-10-0886
OAAI
Vizeacoumar, Franco J.; Arnold, Roland; Vizeacoumar, Frederick S.; Chandrashekhar, Megha; Buzina, Alla; Young, Jordan T. F.; Kwan, Julian H. M.; Sayad, Azin; Mero, Patricia; Lawo, Steffen; Tanaka, Hiromasa; Brown, Kevin R.; Baryshnikova, Anastasia; Mak, Anthony B.; Fedyshyn, Yaroslav; Wang, Yadong; Brito, Glauber C.; Kasimer, Dahlia; Makhnevych, Taras; Ketela, Troy; Datti, Alessandro; Babu, Mohan; Emili, Andrew; Pelletier, Laurence; Wrana, Jeff; Wainberg, Zev; Kim, Philip M.; Rottapel, Robert; O'Brien, Catherine A.; Andrews, Brenda; Boone, Charles; Moffat, Jason
The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination
MOLECULAR CELL
IF16.6
2010-11-01127
OA
O'Donnell, Lara; Panier, Stephanie; Wildenhain, Jan; Tkach, Johnny M.; Al-Hakim, Abdallah; Landry, Marie-Claude; Escribano-Diaz, Cristina; Szilard, Rachel K.; Young, Jordan T. F.; Munro, Meagan; Canny, Marella D.; Kolas, Nadine K.; Zhang, Wei; Harding, Shane M.; Ylanko, Jarkko; Mendez, Megan; Mullin, Michael; Sun, Thomas; Habermann, Bianca; Datti, Alessandro; Bristow, Robert G.; Gingras, Anne-Claude; Tyers, Michael D.; Brown, Grant W.; Durocher, Daniel

研究方向

暂未获取到该数据
D
Daniel Durocher
H 指数:76论文数:208被引数:2.9万
A
Artur Veloso
H 指数:22论文数:73被引数:2,354
A
Anne Roulston
H 指数:28论文数:96被引数:4,850
M
Michal Zimmermann
H 指数:23论文数:84被引数:6,709
M
Meagan Munro
H 指数:13论文数:28被引数:3,451
M
Michael Zinda
H 指数:34论文数:230被引数:4,021
A
Alessandro Datti
H 指数:44论文数:220被引数:7,723
G
Grant W. Brown
H 指数:53论文数:216被引数:1.3万
A
Alejandro Álvarez-Quilón
H 指数:15论文数:34被引数:2,369
V
Vivek Bhaskaran
H 指数:10论文数:43被引数:762