Jeremy Saklatvala - Publications, H-index & Citations

Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38

IF2.7

2023-03-28

388

OAAI

Lasa, M; Mahtani, KR; Finch, A; Brewer, G; Saklatvala, J; Clark, AR

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

IF2.7

2023-03-28

340

OAAI

Lasa, M; Abraham, SM; Boucheron, C; Saklatvala, J; Clark, AR

Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38

IF2.7

2023-03-28

434

OAAI

Mahtani, KR; Brook, M; Dean, JLE; Sully, G; Saklatvala, J; Clark, AR

Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways

IF2.7

2023-03-27

231

OAAI

Lasa, M; Brook, M; Saklatvala, J; Clark, AR

The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR

IF2.7

2023-03-27

251

OAAI

Brook, M; Tchen, CR; Santalucia, T; McIlrath, J; Arthur, JSC; Saklatvala, J; Clark, AR

JNK-DEPENDENT MODULATION OF THE PROTEASE SECRETOME PROFILE OF OSTEOARTHRITIC CARTILAGE

IF2.7

2023-03-27

279

OAAI

Dean, JLE; Wait, R; Mahtani, KR; Sully, G; Clark, AR; Saklatvala, J

WHOLE BLOOD RNA TRANSCRIPTIONAL REGULATION AFTER ACUTE KNEE INJURY IS ASSOCIATED WITH CLINICAL OUTCOMES: EARLY DATA FROM THE KICK STUDY

IF9

2018-04-01

OAAI

Ismail, H. M.; Troeberg, L.; Vincent, T. L.; Saklatvala, J.

Rapid Activation of Transforming Growth Factor β-Activated Kinase 1 in Chondrocytes by Phosphorylation and K63-Linked Polyubiquitination Upon Injury to Animal Articular Cartilage

IF9

2017-04-01

OAAI

Chanalaris, A.; Willliams, A.; Saklatvala, J.; Vincent, T. L.; Watt, F. E.

Acute Molecular Changes in Synovial Fluid Following Human Knee Injury: Association With Early Clinical Outcomes

IF10.9

2017-02-27

OAAI

Ismail, Heba M.; Didangelos, Athanasios; Vincent, Tonia L.; Saklatvala, Jeremy

SYNOVIAL FLUID BIOMARKERS OF THE ACUTE KNEE INJURY RESPONSE ARE ASSOCIATED WITH EARLY CLINICAL OUTCOMES

IF10.9

2016-08-25

OAAI

Watt, Fiona E.; Paterson, Erin; Freidin, Andrew; Kenny, Mark; Judge, Andrew; Saklatvala, Jeremy; Williams, Andy; Vincent, Tonia L.

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2016-06-01

PREAI

Watt, F. E.; Paterson, E.; Freidin, A.; Kenny, M.; Judge, A.; Saklatvala, J.; Williams, A.; Vincent, T.

JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis

MOLECULAR CHANGES IN SYNOVIAL FLUID FOLLOWING HUMAN KNEE INJURY ARE ASSOCIATED WITH EARLY CLINICAL OUTCOMES

IF10.9

2016-04-27

OAAI

Ismail, Heba M.; Miotla-Zarebska, Jadwiga; Troeberg, Linda; Tang, Xiaodi; Stott, Bryony; Yamamoto, Kazuhiro; Nagase, Hideaki; Fosang, Amanda J.; Vincent, Tonia L.; Saklatvala, Jeremy

TNFAIP6 AND SAA1 MRNA LEVELS ARE ELEVATED IN PERIPHERAL BLOOD CELLS FOLLOWING DESTABILISING KNEE INJURIES

IF9

2016-04-01

OAAI

Watt, F. E.; Paterson, E.; Freidin, A.; Kenny, M.; Judge, A.; Saklatvala, J.; Williams, A.; Vincent, T.

DIFFERENTIAL INFLAMMATORY GENE EXPRESSION PATTERNS IN JNK2 KNOCKOUT MICE IN RESPONSE TO IL1, CARTILAGE INJURY AND SURGICALLY INDUCED OSTEOARTHRITIS

IF9

2016-04-01

OAAI

Chanalaris, A.; Paterson, E.; Freidin, A.; Kenny, M.; Saklatvala, J.; Williams, A.; Watt, F. E.; Vincent, T. L.

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin 通过mRNA去稳定蛋白Tristetraprolin的靶向突变来显着抑制炎症

IF9

2016-04-01

OAAI

Ismail, H. M.; Chanalaris, A.; Miotla-Zarebska, J.; Vincent, T. L.; Saklatvala, J.

JOURNAL OF IMMUNOLOGY

IF3.4

2015-07-01

OAAI

Ross, Ewan A.; Smallie, Tim; Ding, Qize; O'Neil, John D.; Cunliffe, Helen E.; Tang, Tina; Rosner, Dalya R.; Klevernic, Iva; Morrice, Nicholas A.; Monaco, Claudia; Cunningham, Adam F.; Buckley, Christopher D.; Saklatvala, Jeremy; Dean, Jonathan L.; Clark, Andrew R.

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide 双特异性磷酸酶1和曲斯特普林协同调节巨噬细胞对脂多糖的反应

JOURNAL OF IMMUNOLOGY

IF3.4

2015-07-01

OAAI

Smallie, Tim; Ross, Ewan A.; Ammit, Alaina J.; Cunliffe, Helen E.; Tang, Tina; Rosner, Dalya R.; Ridley, Michael L.; Buckley, Christopher D.; Saklatvala, Jeremy; Dean, Jonathan L.; Clark, Andrew R.

Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis

IF10.9

2015-06-26

OAAI

Ismail, Heba M.; Yamamoto, Kazuhiro; Vincent, Tonia L.; Nagase, Hideaki; Troeberg, Linda; Saklatvala, Jeremy