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A Phase 3, 28-week, multicentre, randomised, double-blind, placebo-controlled trial (OA-10) to evaluate the efficacy and safety of a single injection of lorecivivint in the target knee joint of moderately to severely symptomatic osteoarthritis patients 一项为期28周的III期、多中心、随机、双盲、安慰剂对照试验(OA-10),旨在评估中度至重度症状性骨关节炎患者靶膝关节单次注射lorecivivint的疗效和安全性。 Yazici, Y.; Tambiah, J. R. S.; Swearingen, C. J.; Lopez, V. A.; Kennedy, S.; Fineman, M. S.; Simsek, I.; Solomon, E.; McAlindon, T. E. 分享 收藏
A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis Yazici, Y.; McAlindon, T. E.; Gibofsky, A.; Lane, N. E.; Lattermann, C.; Skrepnik, N.; Swearingen, C. J.; Simsek, I.; Ghandehari, H.; DiFrancesco, A.; Gibbs, J.; Tambiah, J. R. S.; Hochberg, M. C. 分享 收藏
Lorecivivint, a Novel IntraarticularCDC-Like Kinase 2 and Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor and Wnt Pathway Modulator for the Treatment of Knee Osteoarthritis: A PhaseIIRandomized Trial Yazici, Yusuf; McAlindon, Timothy E.; Gibofsky, Allan; Lane, Nancy E.; Clauw, Daniel; Jones, Morgan; Bergfeld, John; Swearingen, Christopher J.; DiFrancesco, Anita; Simsek, Ismail; Tambiah, Jeyanesh; Hochberg, Marc C. 分享 收藏
Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behcet's disease severity 循环LL37将血浆细胞外囊泡靶向免疫细胞并加剧白塞病的严重程度 Kahraman, Tamer; Gucluler, Gozde; Simsek, Ismail; Yagci, Fuat Cem; Yildirim, Muzaffer; Ozen, Can; Dinc, Ayhan; Gursel, Mayda; Ikromzoda, Lolai; Sutlu, Tolga; Gay, Stephen; Gursel, Ihsan 分享 收藏
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DISCREPANCY BETWEEN PATIENTS AND PHYSICIANS ON GLOBAL DISEASE ASSESSMENT OF RA AND ITS DETERMINANTS: AN ANALYSIS FROM THE TRAV COHORT Tascilar, K.; Hatemi, G.; Inanc, N.; Simsek, I.; Swearingen, C.; Cinar, M.; Ugurlu, S.; Yilmaz, S.; Ozen, G.; Pay, S.; Direskeneli, H.; Yazici, Y. 分享 收藏
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A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population ERAP1的多态性与土耳其人群对强直性脊柱炎的易感性相关 Cinar, Muhammet; Akar, Hatice; Yilmaz, Sedat; Simsek, Ismail; Karkucak, Mutlu; Sagkan, Rahsan Ilikci; Pekel, Aysel; Erdem, Hakan; Avci, Ismail Yasar; Acikel, Cengizhan; Musabak, Ugur; Tunca, Yusuf; Pay, Salih 分享 收藏
Relationship of ultrasonographic findings with synovial angiogenesis modulators in different forms of knee arthritides Gok, Mahmut; Erdem, Hakan; Gogus, Feride; Yilmaz, Sedat; Karadag, Omer; Simsek, Ismail; Sagkan, Rahsan Ilikci; Saglam, Mutlu; Musabak, Ugur; Dinc, Ayhan; Pay, Salih 分享 收藏
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Evaluation of the short-term efficacy of NSAIDs on patients with active ankylosing spondylitis in daily practice: a 3-month, longitudinal, observational study (vol 30, pg 331, 2010) Cinar, Muhammet; Dinc, Ayhan; Simsek, Ismail; Erdem, Hakan; Koc, Bayram; Pay, Salih; Kilic, Selim 分享 收藏
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