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J

John Hood

endeavor biomedicines

36H指数
102论文数
9.6K被引数
收录论文 23
发表时间
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Taladegib for the treatment of idiopathic pulmonary fibrosis (ENV-IPF-101): a multicentre, randomised, double-blind, placebo-controlled, phase 2a trial塔拉地吉用于特发性肺纤维化治疗的试验（ENV-IPF-101）：一项多中心、随机、双盲、安慰剂对照的2a期临床试验
errThe Lancet Respiratory Medicine
IF32.8
err2025-09-30
err0
PREAI
errT M Maher; J G Goldin; J Hood; J Pitman; M de los Rios; B P Hobbs; A B Yu-Lin; I Buendia-Roldan; F Thien; J W Song; P C Perea; A Ramírez-Rivera; A DiFrancesco
err分享
err收藏
A small-molecule inhibitor of the Wnt pathway, lorecivivint (SM04690), as a potential disease-modifying agent for the treatment of degenerative disc disease
errSPINE JOURNAL
IF4.7
err2020-09-01
err9
errOAAI
errDeshmukh, Vishal; Ibanez, Maureen; Hu, Haide; Cahiwat, Joseph; Wei, Ying; Stewart, Joshua; Hood, John; Yazici, Yusuf
err分享
err收藏
Fedratinib in myelofibrosis
errBLOOD ADVANCES
IF7.1
err2020-04-28
err72
errOAAI
errMullally, Ann; Hood, John; Harrison, Claire; Mesa, Ruben
err分享
err收藏
The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models
errCANCER LETTERS
IF10.1
err2020-03-01
err99
errOAAI
errTam, Betty Y.; Chiu, Kevin; Chung, Heekyung; Bossard, Carine; Nguyen, John Duc; Creger, Emily; Eastman, Brian W.; Mak, Chi Ching; Ibanez, Maureen; Ghias, Abdullah; Cahiwat, Joseph; Do, Long; Cho, Shawn; Nguyen, Jackie; Deshmukh, Vishal; Stewart, Josh; Chen, Chiao-Wen; Barroga, Charlene; Dellamary, Luis; Kc, Sunil K.; Phalen, Timothy J.; Hood, John; Cha, Steven; Yazici, Yusuf
err分享
err收藏
Modulation of the Wnt pathway through inhibition of CLK2 and DYRK1A by lorecivivint as a novel, potentially disease-modifying approach for knee osteoarthritis treatmentLorecivivivint通过抑制CLK2和DYRK1A来调节Wnt途径，作为一种新的，潜在的疾病修饰方法，用于治疗膝骨关节炎
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2019-09-01
err131
errOAAI
errDeshmukh, V.; O'Green, A. L.; Bossard, C.; Seo, T.; Lamangan, L.; Ibanez, M.; Ghias, A.; Lai, C.; Do, L.; Cho, S.; Cahiwat, J.; Chiu, K.; Pedraza, M.; Anderson, S.; Harris, R.; Dellamary, L.; Kc, S.; Barroga, C.; Melchior, B.; Tamz, B.; Kennedy, S.; Tambiah, J.; Hood, J.; Yazici, Y.
err分享
err收藏
A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2018-01-01
err192
errOAAI
errDeshmukh, V.; Hu, H.; Barroga, C.; Bossard, C.; Kc, S.; Dellamary, L.; Stewart, J.; Chiu, K.; Ibanez, M.; Pedraza, M.; Seo, T.; Do, L.; Cho, S.; Cahiwat, J.; Tam, B.; Tambiah, J. R. S.; Hood, J.; Lane, N. E.; Yazici, Y.
err分享
err收藏
A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study一种新型Wnt途径抑制剂SM04690，用于治疗中度至重度膝骨关节炎: 一项为期24周的随机对照1期研究的结果
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2017-10-01
err105
errOAAI
errYazici, Y.; McAlindon, T. E.; Fleischmann, R.; Gibofsky, A.; Lane, N. E.; Kivitz, A. J.; Skrepnik, N.; Armas, E.; Swearingen, C. J.; DiFrancesco, A.; Tambiah, J. R. S.; Hood, J.; Hochberg, M. C.
err分享
err收藏
DISCOVERY OF A SMALL MOLECULE INHIBITOR OF THE WNT PATHWAY (SM04755) AS A POTENTIAL TOPICAL TREATMENT FOR TENDINOPATHY
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2017-04-01
err0
errOAAI
errDeshmukh, V.; Seo, T.; Ibanez, M.; Hofilena, B.; Kc, S.; Dellamary, L.; Stewart, J.; Hood, J.; Yazici, Y.
err分享
err收藏
DISCOVERY OF A SMALL MOLECULE INHIBITOR OF THE WNT PATHWAY (SM04690) AS A POTENTIAL TREATMENT FOR DEGENERATIVE DISC DISEASE
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2017-04-01
err3
errOAAI
errBarroga, C.; Deshmukh, V.; Kc, S.; Dellamary, L.; Hood, J.; Steward, J.; Hu, H.; Yazici, Y.
err分享
err收藏
DISCOVERY OF A SMALL MOLECULE INHIBITOR OF THE WNT PATHWAY (SM04690) AS A POTENTIAL DISEASE MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2016-06-01
err2
PREAI
errHood, J.; Barroga, C.; Hu, Y.; Deshmukh, V.
err分享
err收藏
SAFETY, CLINICAL AND IMAGING OUTCOMES OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT INHIBITOR (SM04690) IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE: EXPLORATORY ANALYSIS OF RESULTS FROM A 24 WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 1 STUDY
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2016-06-01
err0
PREAI
errYazici, Y.; McAlindon, T. E.; Fleischmann, R. M.; Gibofsky, A.; Lane, N. E.; Kivitz, A. J.; Majumdar, S.; Strand, V.; Swearingen, C. J.; DiFrancesco, A.; Tambiah, J.; Hood, J.; Hochberg, M. C.
err分享
err收藏
DISCOVERY OF A SMALL MOLECULE INHIBITOR OF THE WNT PATHWAY (SM04690) AS A POTENTIAL DISEASE MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2016-04-01
err6
errOAAI
errHood, J. D.; Deshmukh, V.; Barroga, C.; Hu, Y.
err分享
err收藏
Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients
errONCOGENE
IF7.3
err2009-02-23
err104
errOAAI
errSamanta, A. K.; Chakraborty, S. N.; Wang, Y.; Kantarjian, H.; Sun, X.; Hood, J.; Perrotti, D.; Arlinghaus, R. B.
err分享
err收藏
TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic cells derived from myeloproliferative disorder patients with JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation negative patients
errLEUKEMIA
IF13.4
err2008-03-20
err97
PREAI
errLasho, T. L.; Tefferi, A.; Hood, J. D.; Verstovsek, S.; Gilliland, D. G.; Pardanani, A.
err分享
err收藏
Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): A topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2008-02-27
err59
PREAI
errPalanki, Moorthy S. S.; Akiyama, Hideo; Campochiaro, Peter; Cao, Jianguo; Chow, Chun P.; Dellamary, Luis; Doukas, John; Fine, Richard; Gritzen, Colleen; Hood, John D.; Hu, Steven; Kachi, Shu; Kang, Xinshan; Klebansky, Boris; Kousba, Ahmed; Lohse, Dan; Mak, Chi Ching; Martin, Michael; McPherson, Andrew; Pathak, Ved P.; Renick, Joel; Soll, Richard; Umeda, Naoyasu; Yee, Shiyin; Yokoi, Katsutoshi; Zeng, Binqi; Zhu, Hong; Noronha, Glenn
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err收藏
Discovery of 3,3-(2,4-Diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2007-08-09
err59
PREAI
errPalanki, Moorthy S. S.; Dneprovskaia, Elena; Doukas, John; Fine, Richard M.; Hood, John; Kang, Xinshan; Lohse, Dan; Martin, Michael; Noronha, Glenn; Soll, Richard M.; Wrasidlo, Wolfgang; Yee, Shiyin; Zhu, Hong
err分享
err收藏
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
errLEUKEMIA
IF13.4
err2007-05-31
err260
PREAI
errPardanani, A.; Hood, J.; Lasho, T.; Levine, R. L.; Martin, M. B.; Noronha, G.; Finke, C.; Mak, C. C.; Mesa, R.; Zhu, H.; Soll, R.; Gilliland, D. G.; Tefferi, A.
err分享
err收藏
Isoform-selective PI3K inhibitors as novel therapeutics for the treatment of acute myocardial infarction
errBIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
err2007-03-20
err24
PREAI
errDoukas, J.; Wrasidlo, W.; Noronha, G.; Dneprovskaia, E.; Hood, J.; Soll, R.
err分享
err收藏
Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injury
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2006-12-26
err161
errOAAI
errDoukas, John; Wrasidlo, Wolfgang; Noronha, Glenn; Dneprovskaia, Elena; Fine, Richard; Weis, Sara; Hood, John; DeMaria, Anthony; Soll, Richard; Cheresh, David
err分享
err收藏
Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase.
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2002-06-01
err152
errOAAI
errWakasugi, K; Slike, BM; Hood, J; Ewalt, KL; Cheresh, DA; Schimmel, P
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
H
Hagop M. Kantarjian
H 指数: 230 · 论文数: 5.5K
A
Ayalew Tefferi
H 指数: 152 · 论文数: 2.1K
R
Ross L. Levine
H 指数: 147 · 论文数: 1.5K
M
Martin A. Schwartz
H 指数: 117 · 论文数: 924
D
David A. Cheresh
H 指数: 116 · 论文数: 415
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