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PHI-101, a Novel FLT3 TKI, Shows Clinical Efficacy in Relapsed/Refractory FLT3-Mutated AML PHI-101，一种新型FLT3 TKI，在FLT3突变型复发性/难治性AML中显示出临床疗效 Shin, Dong-Yeop; Yoon, Sung-Soo; Hong, Junshik; Lee, Je-Hwan; Jang, Jun-Ho; Cheong, June-won; Shin, Ho-Jin; Lee, Jeong-Ok; Lee, Yoo Jin; Ahn, Jae-Sook; Cho, Byoung-Sik; Kim, Hee-Je; Clarey, Joseph; Sung, Gi-Jun; Im, Jeejin; Nam, Ky-Youb; Han, June; Kim, Kyu-Tae; Yoon, Jeonghyeok; Nguyen, Bao; Li, Li; Small, Donald 分享 收藏
Targeting rapid TKI-induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia Seale, Tessa S.; Li, Li; Bruner, J. Kyle; Chou, Melody; Nguyen, Bao; Seo, Jaesung; Zhu, Ruiqi; Levis, Mark J.; Pratilas, Christine A.; Small, Donald 分享 收藏
Inhibition of NOTCH4 sensitizes FLT3/ITD acute myeloid leukemia cells to FLT3 tyrosine kinase inhibition Zhu, Ruiqi; Shirley, Courtney M.; Chu, S. Haihua; Li, Li; Nguyen, Bao H.; Seo, Jaesung; Wu, Min; Seale, Tessa; Duffield, Amy S.; Staudt, Louis M.; Levis, Mark; Hu, Yu; Small, Donald 分享 收藏
PHI-101 synergizes with chemotherapy and venetoclax in preclinical models of acute myeloid leukemia Hwang, Hee-sun; Sung, Gi-Jun; Kim, Kyung-Ah; Nam, Ky-Youb; Kim, Kyu-Tae; Han, June H.; Yoon, Jeong-Hyeok; Nguyen, Bao; Li, Li; Seale, Tessa; Small, Donald 分享 收藏
NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia Matsukawa, Toshihiro; Yin, Mianmian; Nigam, Nupur; Negi, Vijay; Li, Li; Small, Donald; Zhu, Yuelin J.; Walker, Robert L.; Meltzer, Paul S.; Aplan, Peter D. 分享 收藏
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FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children's Oncology Group trial AALL0631 (Feb, 10.1038/s41375-021-01177-6, 2021) Brown, Patrick A.; Kairalla, John A.; Hilden, Joanne M.; Dreyer, ZoAnn E.; Carroll, Andrew J.; Heerema, Nyla A.; Wang, Cindy; Devidas, Meenakshi; Gore, Lia; Salzer, Wanda L.; Winick, Naomi J.; Carroll, William L.; Raetz, Elizabeth A.; Borowitz, Michael J.; Small, Donald; Loh, Mignon L.; Hunger, Stephen P. 分享 收藏
FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children's Oncology Group trial AALL0631 Brown, Patrick A.; Kairalla, John A.; Hilden, Joanne M.; Dreyer, ZoAnn E.; Carroll, Andrew J.; Heerema, Nyla A.; Wang, Cindy; Devidas, Meenakshi; Gore, Lia; Salzer, Wanda L.; Winick, Naomi J.; Carroll, William L.; Raetz, Elizabeth A.; Borowitz, Michael J.; Small, Donald; Loh, Mignon L.; Hunger, Stephen P. 分享 收藏
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A novel RBMX-TFE3 gene fusion in a highly aggressive pediatric renal perivascular epithelioid cell tumor Argani, Pedram; Zhang, Lei; Sung, Yun-Shao; White, Marissa J.; Miller, Karin; Hopkins, Mark; Small, Donald; Pratilas, Christine A.; Swanson, David; Dickson, Brendan; Antonescu, Cristina R. 分享 收藏
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Dual binding motifs underpin the hierarchical association of perilipins1-3 with lipid droplets Ajjaji, Dalila; Ben M'barek, Kalthoum; Mimmack, Michael L.; England, Cheryl; Herscovitz, Haya; Dong, Liang; Kay, Richard G.; Patel, Satish; Saudek, Vladimir; Small, Donald M.; Savage, David B.; Thiam, Abdou Rachid 分享 收藏
Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies Bruner, J. Kyle; Ma, Hayley S.; Li, Li; Qin, Alice Can Ran; Rudek, Michelle A.; Jones, Richard J.; Levis, Mark J.; Pratz, Keith W.; Pratilas, Christine A.; Small, Donald 分享 收藏
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Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia Lim, Yiting; Gondek, Lukasz; Li, Li; Wang, Qiuju; Ma, Haley; Chang, Emily; Huso, David L.; Foerster, Sarah; Marchionni, Luigi; McGovern, Karen; Watkins, David Neil; Peacock, Craig D.; Levis, Mark; Smith, Bruce Douglas; Merchant, Akil A.; Small, Donald; Matsui, William 分享 收藏
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