Akiko Itai - Publications, H-index & Citations

Akiko Itai

Institute of Science Tokyo

44H指数

280论文数

6.3K被引数

收录论文 29

发表时间

Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-08-08

PREAI

Kato, Terukazu; Fukao, Keita; Ohara, Takafumi; Naya, Noriyuki; Tokuyama, Ryukou; Muto, Susumu; Fukasawa, Hiroshi; Itai, Akiko; Matsumura, Ken-ichi

Discovery and structure-activity relationship study of 2-piperazinyl-benzo- thiazole derivatives as potent and selective PPARδ agonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-03-01

PREAI

Kato, Terukazu; Ohara, Takafumi; Suzuki, Naoyuki; Naya, Noriyuki; Fukao, Keita; Tokuyama, Ryukou; Muto, Susumu; Fukasawa, Hiroshi; Itai, Akiko; Matsumura, Ken-ichi

A novel IkB kinase inhibitor attenuates ligature-induced periodontal disease in mice

JOURNAL OF PERIODONTAL RESEARCH

IF3.4

2018-10-08

PREAI

Kure, Keitetsu; Sato, Hiroki; Suzuki, Jun-ichi; Itai, Akiko; Aoyama, Norio; Izumi, Yuichi

TARGETING IKKβ PREVENTS INFLAMMATION-INDUCED PRETERM DELIVERY BY INHIBITING INTERLEUKIN-6 PRODUCTION FROM AMNIOTIC CELLS

PLACENTA

IF2.5

2016-10-01

PREAI

Toda, Aska; Sawada, Kenjiro; Itai, Akiko; Kimura, Tadashi

IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment

MOLECULAR CANCER THERAPEUTICS

IF5.5

2015-04-09

OAAI

Kinose, Yasuto; Sawada, Kenjiro; Makino, Hiroshi; Ogura, Tomonori; Mizuno, Tomoko; Suzuki, Noriko; Fujikawa, Tomoyuki; Morii, Eiichi; Nakamura, Koji; Sawada, Ikuko; Toda, Aska; Hashimoto, Kae; Isobe, Aki; Mabuchi, Seiji; Ohta, Tsuyoshi; Itai, Akiko; Morishige, Ken-ichirou; Kurachi, Hirohisa; Kimura, Tadashi

IκB Kinase-β Inhibitor IMD-0354 Beneficially Suppresses Retinal Vascular Permeability in Streptozotocin-Induced Diabetic Mice

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2014-10-10

PREAI

Lennikov, Anton; Hiraoka, Miki; Abe, Akira; Ohno, Shigeaki; Fujikawa, Tomoyuki; Itai, Akiko; Ohguro, Hiroshi

TARGETING IKKβ SIGNALING PREVENTS PRETERM DELIVERY THROUGH INHIBITION OF INTERLEUKIN-6 PRODUCTION FROM AMNIOTIC MESENCHYMAL CELLS.

PLACENTA

IF2.5

2014-10-01

PREAI

Toda, Aska; Sawada, Kenjiro; Fujikawa, Tomoyuki; Hashimoto, Kae; Sawada, Ikuko; Kinose, Yasuto; Itai, Akiko; Kimura, Tadashi

Pathophysiological roles of nuclear factor kappaB (NF-kB) in pulmonary arterial hypertension: effects of synthetic selective NF-kB inhibitor IMD-0354

CARDIOVASCULAR RESEARCH

IF13.3

2013-04-30

OAAI

Hosokawa, Susumu; Haraguchi, Go; Sasaki, Akihito; Arai, Hirokuni; Muto, Susumu; Itai, Akiko; Doi, Shozaburo; Mizutani, Shuki; Isobe, Mitsuaki

Novel IκκB kinase inhibitors for treatment of nuclear factor-κκB-related diseases

EXPERT OPINION ON INVESTIGATIONAL DRUGS

IF4.1

2011-02-11

PREAI

Suzuki, Jun-ichi; Ogawa, Masahito; Muto, Susumu; Itai, Akiko; Isobe, Mitsuaki; Hirata, Yasunobu; Nagai, Ryozo

The Effects of Pharmacologic Plasminogen Activator Inhibitor-1 Inhibition in Acute and Chronic Rejection in Murine Cardiac Allografts

TRANSPLANTATION

IF5

2011-01-15

OAAI

Ogawa, Masahito; Suzuki, Jun-ichi; Yamaguchi, Yoichi; Muto, Susumu; Itai, Akiko; Hirata, Yasunobu; Isobe, Mitsuaki; Nagai, Ryozo

Effects of specific chemical suppressors of plasminogen activator inhibitor-1 in cardiovascular diseases

EXPERT OPINION ON INVESTIGATIONAL DRUGS

IF4.1

2011-01-03

PREAI

Suzuki, Jun-ichi; Ogawa, Masahito; Muto, Susumu; Itai, Akiko; Hirata, Yasunobu; Isobe, Mitsuaki; Nagai, Ryozo

IκB kinase β inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma

CLINICAL AND EXPERIMENTAL ALLERGY

IF5.2

2010-12-14

PREAI

Ogawa, H.; Azuma, M.; Muto, S.; Nishioka, Y.; Honjo, A.; Tezuka, T.; Uehara, H.; Izumi, K.; Itai, A.; Sone, S.

A Pivotal Role of Plasminogen Activator Inhibitor-1 in Myocardial Ischemia

JOURNAL OF CARDIAC FAILURE

IF8.2

2009-09-01

PREAI

Nakajima, Takuya; Nagashima, Ayako; Ogawa, Masahito; Suzuki, Jun-Ichi; Muto, Susumu; Yamaguchi, Yoichi; Itai, Akiko; Isobe, Mitsuaki

Effectiveness of IκB kinase inhibitors in murine colitis-associated tumorigenesis

JOURNAL OF GASTROENTEROLOGY

IF5.5

2009-06-26

PREAI

Hayakawa, Yoku; Maeda, Shin; Nakagawa, Hayato; Hikiba, Yohko; Shibata, Wataru; Sakamoto, Kei; Yanai, Ayako; Hirata, Yoshihiro; Ogura, Keiji; Muto, Susumu; Itai, Akiko; Omata, Masao

Topical application with a new NF-κB inhibitor improves atopic dermatitis in NC/NgaTnd mice

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2007-04-01

OAAI

Tanaka, Akane; Muto, Susumu; Jung, Kyungsook; Itai, Akiko; Matsuda, Hiroshi

A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2006-11-01

PREAI

Haraguchi, Go; Suzuki, Jun-ichi; Kosuge, Hisanori; Ogawa, Masahito; Koga, Noritaka; Muto, Susumu; Itai, Akiko; Kagechika, Hiroyuki; Shudo, Koichi; Isobe, Mitsuaki

A novel IκB kinase-β inhibitor ameliorates bleomycin-induced pulmonary fibrosis in mice 一种新的i κ b激酶-β 抑制剂改善博来霉素诱导的小鼠肺纤维化

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2006-05-01

PREAI

Inayama, M; Nishioka, Y; Azuma, M; Muto, S; Aono, Y; Makino, H; Tani, K; Uehara, H; Izumi, K; Itai, A; Sone, S

Effective handling of induced-fit motion in flexible docking

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2006-03-10

PREAI

Mizutani, Miho Yamada; Takamatsu, Yoshihiro; Ichinose, Tazuko; Nakamura, Kensuke; Itai, Akiko