未登录Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC洛那法尼耐药性的分子机制：由呼吸道合胞病毒融合糖蛋白富半胱氨酸区域的突变赋予，以及洛那法尼衍生的抗病毒PROTAC的发现
Yang, Qi; Xue, Bao; Qiu, Xianjie; Yang, Kaixin; Tang, Jielin; Zhou, Anqi; Zou, Jingjing; Mao, Yuhan; Zhong, Jiayi; Zhou, Yuan; Zhang, Wei; Zhang, Qiong; Xiao, Qingyu; Tang, Wei; Li, Zhiyu; Ye, Wencai; Zou, Gang; Peng, Wei; Shang, Jinsai; Xu, Xi; Li, Yixue; Chen, Xinwen .png)
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收藏分享 收藏 分享 收藏 分享 收藏 Xanthochrysanthones A-C, Novel Lobster-Shape Cinnamoyltriketone Dimers with Antiviral Activities from Xanthostemon chrysanthus黄蝉三酮A-C，来自Xanthostemon chrysanthus的新型龙虾形肉桂酰三酮二聚体，具有抗病毒活性Zhan, Qiong; Liu, Fen; Sun, Biao; Tang, Wei; Cheng, Min-Jing; Jiang, Ren-Wang; Zhang, Qing-Wen; Wu, Zhen-Long; Ye, Wen-Cai; Wang, Lei 分享 收藏 In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic ActivityWang, Shu-Qin; Wang, Xinyu; Guo, Lingling; Chen, Xiao-Xia; Huang, Xiao-Jun; Zhang, Shiqing; Ye, Wen-Cai; Zhang, Xiao-Qi; Shi, Lei; Wang, Ying; Hu, Li-Jun 分享 收藏 Dihydromyricetin mitigates abdominal aortic aneurysm via transcriptional and post-transcriptional regulation of heme oxygenase-1 in vascular smooth muscle cells二氢杨梅素通过调节血管平滑肌细胞中血红素加氧酶-1的转录和转录后水平来缓解腹主动脉瘤Ye, WL; Yang, PL; Jin, M; Zou, JM; Zheng, ZH; Li, YY; Zhang, DM; Ye, WC; Huang, ZN; Wang, JJ; Liu, ZP 分享 收藏 Targeting p62 by sulforaphane promotes autolysosomal degradation of SLC7A11, inducing ferroptosis for osteosarcoma treatmentZou, Qiuming; Zhou, Xiaofeng; Lai, Jianqin; Zhou, Haixia; Su, Jinxuan; Zhang, Zhijing; Zhuang, Xiaosong; Liu, Lili; Yuan, Ruijie; Li, Sijia; Yang, Siyu; Qu, Xinyi; Feng, Jiezhu; Liu, Yongqi; Li, Zisheng; Huang, Shiting; Shi, Zhi; Yan, Yu; Zheng, Zhiming; Ye, Wencai; Qi, Qi 分享 收藏 分享 收藏 Discovery of Potent and Selective CDK4/6 Inhibitors for the Treatment of Chemotherapy-Induced Myelosuppression发现强效且选择性CDK4/6抑制剂，用于治疗化疗诱导的骨髓抑制Shi, Wei; Wang, Rong; Qian, Jianqiang; Wang, Lu; Li, You; Mi, Yahui; Jia, Zhaotong; Pan, Mingshi; Zhang, Xiaoqi; Ye, Wencai; Xiong, Fei; Hu, Xiaolong; Wang, Hao 分享 收藏 分享 收藏 Encapsulation of toxic liquid molecules and adsorption of water pollutants by a versatile pre-organized single crystalline coating material通过一种多功能的预组织单晶涂层材料对有毒液体分子进行封装以及对水污染物的吸附Huang, Wei-Ping; Liu, Jin-Chang; Wang, Feng; Xu, Wei; Tao, Zi-Meng; Middleton, David A.; Liu, Cheng-Dong; Qin, Shu-Qin; Ye, Wen-Cai; Jiang, Ren-Wang 分享 收藏 Thrysaxinones A-F: antibacterial phloroglucinol-terpenoid adducts from Thryptomene saxicolaThrysaxinones A-F：来自Thryptomene saxicola的抗菌间苯三酚-类萜加合物Su, Wei-Fang; Li, Ni-Ping; Cui, Rui-Qin; Liu, Fen; Chen, Mu; Wu, Xin-Yue; Cheng, Min-Jing; Cao, Jia-Qing; Huang, Wei; Zhang, Xiao-Qi; Ye, Wen-Cai; Wang, Lei 分享 收藏 Kopsileuconines A-D: Bisindole alkaloids with cytotoxic activity from Kopsia hainanensisKopsileuconines a-d: 来自海南Kopsia的具有细胞毒活性的双吲哚生物碱Li, Ni-Ping; Chen, Shan-Na; Su, Wei-Fang; Liu, Fen; Li, Lian-Jing; Song, Jian-Guo; Cheng, Min-Jing; Li, Yi-Yi; Chen, Run-Qiang; Lei, Xue-Ping; Ye, Wen-Cai; Wang, Lei 分享 收藏 Targeted isolation of antiviral cinnamoylphloroglucinol-terpene adducts from Cleistocalyx operculatus by building blocks- based molecular networking approach通过基于构建块的分子网络方法靶向隔离来自棘萼的抗病毒肉桂基间苯三酚-萜烯加合物Song, Jianguo; Huang, Ruili; Cai, Jialiao; Wu, Zhenlong; Hu, Lijun; Sun, Wanyang; Huang, Xiaojun; He, Rongrong; Tang, Wei; Ye, Wencai; Wang, Ying 分享 收藏 Therapeutic Targeting of PKM2 Ameliorates NASH Fibrosis Progression in a Macrophage-Specific and Liver-Specific MannerQu, Hengdong; Zhang, Di; Liu, Junli; Deng, Jieping; Xie, Ruoyan; Zhang, Keke; Li, Hongmei; Tao, Ping; Wang, Genshu; Sun, Jian; Luo, Oscar Junhong; Qu, Chen; Ye, Wencai; Hong, Jian 分享 收藏 A new mechanism of respiratory syncytial virus entry inhibition by small-molecule to overcome K394R-associated resistance小分子抑制呼吸道合胞病毒进入以克服K394R-associated阻力的新机制Song, Qiaoyun; Zhu, Haoyue; Qiu, Manlan; Cai, Jialiao; Hu, Yun; Yang, Haixia; Rao, Shuwen; Li, Yaolan; Li, Manmei; Hu, Lijun; Wang, Shuqin; Hong, Jian; Ye, Wencai; Chen, Heru; Wang, Ying; Tang, Wei 分享 收藏 Antiviral C-geranylated flavonoids from Artocarpus communisHuang, Rui -Li; Tang, Wei; Wang, Chaoqun; Yan, Cong; Hu, Yun; Yang, Hai-Xia; Xiang, Hai-Yang; Huang, Xiao-Jun; Hu, Li-Jun; Ye, Wen-Cai; Song, Jian-Guo; Wang, Ying 分享 收藏 Asymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSACheng, Min-Jing; Wu, Yan-Yi; Zeng, Hao; Zhang, Tian-Hong; Hu, Yan-Xia; Liu, Shi-Yi; Cui, Rui-Qin; Hu, Chun-Xia; Zou, Quan-Ming; Li, Chuang-Chuang; Ye, Wen-Cai; Huang, Wei; Wang, Lei 分享 收藏 Discovery of unusual phloroglucinol-triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking通过构建基于模块的分子网络从钩状植物和黄stemon chrysanthus中发现不寻常的间苯三酚-三萜类加合物Zhang, Jinyan; Liu, Fen; Jin, Qian; Li, Xueyi; Zhan, Qiong; Chen, Mu; Wang, Sisi; Wu, Zhenlong; Ye, Wencai; Wang, Lei 分享 收藏 
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