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W

William B. Pratt

university of michigan system

91H指数
313论文数
2.5W被引数
收录论文 52
发表时间
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Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts
errCLINICAL CANCER RESEARCH
IF10.2
err2020-10-01
err14
errOAAI
errMehta, Ranjit K.; Pal, Sanjima; Kondapi, Koushik; Sitto, Merna; Dewar, Cuyler; Devasia, Theresa; Schipper, Matthew J.; Thomas, Dafydd G.; Basrur, Venkatesha; Pai, Manjunath P.; Morishima, Yoshihiro; Osawa, Yoichi; Pratt, William B.; Lawrence, Theodore S.; Nyati, Mukesh K.
err分享
err收藏
Targeting Hsp70 facilitated protein quality control for treatment of polyglutamine diseases
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2019-09-24
err31
errOAAI
errDavis, Amanda K.; Pratt, William B.; Lieberman, Andrew P.; Osawa, Yoichi
err分享
err收藏
Chaperone Activity and Dimerization Properties of Hsp90α and Hsp90β in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery
errMOLECULAR PHARMACOLOGY
IF3
err2018-09-01
err15
errOAAI
errMorishima, Yoshihiro; Mehta, Ranjit K.; Yoshimura, Miyako; Lau, Miranda; Southworth, Daniel R.; Lawrence, Theodore S.; Pratt, William B.; Nyati, Mukesh K.; Osawa, Yoichi
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Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases靶向Hsp90/Hsp70-Based蛋白质量控制治疗成人型神经退行性疾病
errANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
IF0
err2015-01-06
err197
errOAAI
errPratt, William B.; Gestwicki, Jason E.; Osawa, Yoichi; Lieberman, Andrew P.
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Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts
errNEOPLASIA
IF7.7
err2014-02-01
err28
errOAAI
errAhsan, Aarif; Ramanand, Susmita G.; Bergin, Ingrid L.; Zhao, Lilli; Whitehead, Christopher E.; Rehemtulla, Alnawaz; Ray, Dipankar; Pratt, William B.; Lawrence, Theodore S.; Nyati, Mukesh K.
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Destabilization of the Epidermal Growth Factor Receptor (EGFR) by a Peptide That Inhibits EGFR Binding to Heat Shock Protein 90 and Receptor Dimerization
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-09-01
err38
errOAAI
errAhsan, Aarif; Ray, Dipankar; Ramanand, Susmita G.; Hegde, Ashok; Whitehead, Christopher; Rehemtulla, Alnawaz; Morishima, Yoshihiro; Pratt, William B.; Osawa, Yoichi; Lawrence, Theodore S.; Nyati, Mukesh K.
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Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation
errNATURE CHEMICAL BIOLOGY
IF13.7
err2012-12-09
err162
errOAAI
errWang, Adrienne M.; Miyata, Yoshinari; Klinedinst, Susan; Peng, Hwei-Ming; Chua, Jason P.; Komiyama, Tomoko; Li, Xiaokai; Morishima, Yoshihiro; Merry, Diane E.; Pratt, William B.; Osawa, Yoichi; Collins, Catherine A.; Gestwicki, Jason E.; Lieberman, Andrew P.
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Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors
errNEOPLASIA
IF7.7
err2012-08-01
err85
errOAAI
errAhsan, Aarif; Ramanand, Susmita G.; Whitehead, Christopher; Hiniker, Susan M.; Rehemtulla, Alnawaz; Pratt, William B.; Jolly, Shruti; Gouveia, Christopher; Kristy Truong; Van Waes, Carter; Ray, Dipankar; Lawrence, Theodore S.; Nyati, Mukesh K.
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err收藏
Modulation of Heme/Substrate Binding Cleft of Neuronal Nitric-oxide Synthase (nNOS) Regulates Binding of Hsp90 and Hsp70 Proteins and nNOS Ubiquitination
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2012-01-01
err36
errOAAI
errPeng, Hwei-Ming; Morishima, Yoshihiro; Pratt, William B.; Osawa, Yoichi
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C331A Mutant of Neuronal Nitric-oxide Synthase Is Labilized for Hsp70/CHIP (C Terminus of HSC70-interacting Protein)-dependent Ubiquitination
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2010-10-01
err13
errOAAI
errClapp, Kelly M.; Peng, Hwei-Ming; Morishima, Yoshihiro; Lau, Miranda; Walker, Vyvyca J.; Pratt, William B.; Osawa, Yoichi
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Inhibition of Hsp70 by Methylene Blue Affects Signaling Protein Function and Ubiquitination and Modulates Polyglutamine Protein Degradation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2010-05-01
err93
errOAAI
errWang, Adrienne M.; Morishima, Yoshihiro; Clapp, Kelly M.; Peng, Hwei-Ming; Pratt, William B.; Gestwicki, Jason E.; Osawa, Yoichi; Lieberman, Andrew P.
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CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteinsCHIP缺失揭示了E3连接酶在促进信号蛋白和扩展的谷氨酰胺蛋白降解中的功能冗余
errHUMAN MOLECULAR GENETICS
IF3.2
err2008-09-04
err126
errOAAI
errMorishima, Yoshihiro; Wang, Adrienne M.; Yu, Zhigang; Pratt, William B.; Osawa, Yoichi; Lieberman, Andrew P.
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err收藏
Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: Possible mechanisms involved in facilitated and attenuated stress responses
errJOURNAL OF NEUROENDOCRINOLOGY
IF4.1
err2008-07-07
err81
errOAAI
errHoushyar, H; Galigniana, MD; Pratt, WB; Woods, JH
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Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction
errHUMAN MOLECULAR GENETICS
IF3.2
err2006-04-27
err88
errOAAI
errThomas, Monzy; Harrell, Jennifer M.; Morishima, Yoshihiro; Peng, Hwei-Ming; Pratt, William B.; Lieberman, Andrew P.
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Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2005-10-01
err163
PREAI
errMurphy, PJM; Morishima, Y; Kovacs, JJ; Yao, TP; Pratt, WB
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err收藏
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptorHDAC6调节糖皮质激素受体的Hsp90乙酰化和伴侣依赖性激活
errMOLECULAR CELL
IF16.6
err2005-05-01
err1.1K
errOAAI
errKovacs, JJ; Murphy, PJM; Gaillard, S; Zhao, XA; Wu, JT; Nicchitta, CV; Yoshida, M; Toft, DO; Pratt, WB; Yao, TP
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Evidence for glucocorticoid receptor transport on microtubules by dynein
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2004-12-01
err130
errOAAI
errHarrell, JM; Murphy, PJM; Morishima, Y; Chen, HF; Mansfield, JF; Galigniana, MD; Pratt, WB
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Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2004-12-01
err80
errOAAI
errPeng, HM; Morishima, Y; Jenkins, GJ; Dunbar, AY; Lau, M; Patterson, C; Pratt, WB; Osawa, Y
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err收藏
Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2004-12-01
err58
errOAAI
errGaligniana, MD; Morishima, Y; Gallay, PA; Pratt, WB
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err收藏
Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement
errCELLULAR SIGNALLING
IF3.7
err2004-08-01
err270
errOAAI
errPratt, WB; Galigniana, MD; Harrell, JM; DeFranco, DB
err分享
err收藏

研究方向

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