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Songping Liang

Hunan Normal University

H指数:43

被引数:6,815

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TastepepAI: An artificial intelligence platform for taste peptide de novo design

TastepepAI：一个用于味觉肽从头设计的人工智能平台

PLOS COMPUTATIONAL BIOLOGY

IF3.6

2025-10-012

PRE

Discovery of anticancer peptides from natural and generated sequences using deep learning

利用深度学习从天然和生成序列中发现抗癌肽段

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-02-012

PRE

Optimizing Nav1.7-Targeted Analgesics: Revealing Off-Target Effects of Spider Venom-Derived Peptide Toxins and Engineering Strategies for Improvement

ADVANCED SCIENCE

IF14.1

2024-09-090

OA

Development of human lactate dehydrogenase a inhibitors: high-throughput screening, molecular dynamics simulation and enzyme activity assay

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2024-08-102

PRE

Targeting the PDK/PDH axis to reverse metabolic abnormalities by structure-based virtual screening with in vitro and in vivo experiments

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-03-011

PRE

Molecular action mechanisms of two novel and selective calcium release-activated calcium channel antagonists

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2023-12-012

PRE

Dual-sensitive antibacterial peptide nanoparticles prevent dental caries

IF13.3

2022-01-0133

OAAI

Molecular mechanisms of centipede toxin SsTx-4 inhibition of inwardly rectifying potassium channels

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-09-015

OAAI

Glucose-Lipopeptide Conjugates Reveal the Role of Glucose Modification Position in Complexation and the Potential of Malignant Melanoma Therapy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-07-208

PREAI

Engineering of highly potent and selective HNTX-III mutant against hNav1.7 sodium channel for treatment of pain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-0118

OAAI

Molecular diversification of antimicrobial peptides from the wolf spider Lycosa sinensis venom based on peptidomic, transcriptomic, and bioinformatic analyses

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

IF3.4

2020-10-2217

PREAI

Spider venom-derived peptide induces hyperalgesia in Nav1.7 knockout mice by activating Nav1.9 channels

NATURE COMMUNICATIONS

IF15.7

2020-05-0829

OAAI

Scorpion toxin inhibits the voltage-gated proton channel using a Zn2+-like long-range conformational coupling mechanism

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-03-0315

OAAI

Position Effect of Fatty Acid Modification on the Cytotoxicity and Antimetastasis Potential of the Cytotoxic Peptide Lycosin-I

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-11-1823

PREAI

Monosaccharide Analogues of Anticancer Peptide R-Lycosin-I: Role of Monosaccharide Conjugation in Complexation and the Potential of Lung Cancer Targeting and Therapy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-07-0528

PREAI

Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-05-0120

OAAI

Structural Foundation for Insect-Selective Activity of Acylpolyamine Toxins from Spider Araneus ventricosus

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-02-273

PREAI

Purification and Characterization of JZTx-14, a Potent Antagonist of Mammalian and Prokaryotic Voltage-Gated Sodium Channels

IF4

2018-10-103

OAAI

Engineering Gain-of-Function Analogues of the Spider Venom Peptide HNTX-I, A Potent Blocker of the hNaV1.7 Sodium Channel

IF4

2018-09-0411

OAAI

Purification and Characterization of a Novel Insecticidal Toxin, -sparatoxin-Hv2, from the Venom of the Spider Heteropoda venatoria

IF4

2018-06-0717

OAAI