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D

Dietmar Hoffmann

Sanofi-Aventis
H指数:16
被引数:1,644

个人简介

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工作经历

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荣誉奖项

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Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire
COMMUNICATIONS BIOLOGY
IF5.1
2022-10-304
OAAI
Mahendra, Ankit; Haque, Aftabul; Prabakaran, Ponraj; Mackness, Brian C.; Fuller, Thomas P.; Liu, Xiaohua; Kathuria, Sagar, V; Wang, Yui-Hsi; Amatya, Nilesh; Yu, Xiaocong; Hopke, Joern; Hoffmann, Dietmar; Bric-Furlong, Eva; Zhang, Ningning; Cho, Hyun-Suk; Zhang, Ruijun; Sancho, Jose; Saleh, Jacqueline; Rao, Sambasiva P.; Wendt, Maria; Chowdhury, Partha S.
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-02-0551
OA
Shomali, Maysoun; Cheng, Jane; Sun, Fangxian; Koundinya, Malvika; Guo, Zhuyan; Hebert, Andrew T.; McManus, Jessica; Levit, Mikhail N.; Hoffmann, Dietmar; Courjaud, Albane; Arrebola, Rosalia; Cao, Hui; Pollard, Jack; Lee, Joon Sang; Besret, Laurent; Caron, Anne; Bangari, Dinesh S.; Abecassis, Pierre-Yves; Schio, Laurent; El-Ahmad, Youssef; Halley, Frank; Tabart, Michel; Certal, Victor; Thompson, Fabienne; McCort, Gary; Filoche-Romme, Bruno; Cheng, Hong; Garcia-Echeverria, Carlos; Debussche, Laurent; Bouaboula, Monsif
Identification and validation of WRN as a novel synthetic lethality target in context of microsatellite instability
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Ding, Zhihu (Jeff); Zhang, Jing; Pedamallu, Chandra Sekhar; Rowley, Steve; Cheng, Jane; Dai, Shujia; Zhou, Bridget; Koundinya, Malvika; Guo, Zhuyan; Poirier, Stephane; Hopke, Joern; Lennon, Amanda; Buell, Jennifer; Cindhuchao, May; Wong, Karen; Wang, Emma; Protopopov, Alexei; Zhang, Bailin; Hoffmann, Dietmar; Sun, Fangxian; Pollard, Jack; Debussche, Laurent; Bouaboula, Monsif
Sensitivity of liver cancer cell lines to B-catenin knock-down correlates with pathway activation
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Ding, Zhihu (Jeff); Shi, Chaomei; Jiang, Lan; Tolstykh, Tatiana; Cao, Hui; Bangari, Dinesh; Ryan, Susan; Jin, Taiguang; Levit, Mikhail; Mamaat, Karl; Yu, Qunyan; Qu, Hui; Hopke, Joern; Cindhuchao, May; Hoffmann, Dietmar; Sun, Fangxian; Helms, Mike; Jahn-Hofmann, Kerstin; Scheidler, Sabine; Fang, Douglas; Schweizer, Liang; Pollard, Jack; Winter, Christopher; Wiederschain, Dmitri
Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2015-01-01137
OAAI
Deng, Gejing; Shen, Junqing; Yin, Ming; McManus, Jessica; Mathieu, Magali; Gee, Patricia; He, Timothy; Shi, Chaomei; Bedel, Olivier; McLean, Larry R.; Le-Strat, Frank; Zhang, Ying; Marquette, Jean-Pierre; Gao, Qiang; Zhang, Bailin; Rak, Alexey; Hoffmann, Dietmar; Rooney, Eamonn; Vassort, Aurelie; Englaro, Walter; Li, Yi; Patel, Vinod; Adrian, Francisco; Gross, Stefan; Wiederschain, Dmitri; Cheng, Hong; Licht, Stuart
Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells
NUCLEIC ACIDS RESEARCH
IF13.1
2014-12-3042
OAAI
Wagenaar, Timothy R.; Tolstykh, Tatiana; Shi, Chaomei; Jiang, Lan; Zhang, JingXin; Li, Zhifang; Yu, Qunyan; Qu, Hui; Sun, Fangxian; Cao, Hui; Pollard, Jack; Dai, Shujia; Gao, Qiang; Zhang, Bailin; Arlt, Heike; Cindhuchao, May; Hoffmann, Dietmar; Light, Madelyn; Jensen, Karin; Hopke, Joern; Newcombe, Richard; Garcia-Echeverria, Carlos; Winter, Christopher; Zabludoff, Sonya; Wiederschain, Dmitri
PTK7 as a potential therapeutic target in ovarian cancer
CANCER RESEARCH
IF16.6
2014-10-010
PRE
Ding, Zhihu; Lennon, Amanda; Perron, Keli; Harper, David; Su, Hui; Wolfram, Meredith; Murtie, Joshua; Licht, Stuart; Pinckney, Jason; Simonds-Mannes, Helene; Bishop, Kimberly; Gavigan, Julie-Ann; Bangari, Dinesh; Magnay, Maureen; Weber, William; Reczek, David; Brondyk, William; Drewett, Vicky; Trombe, Marc; Hoffmann, Dietmar; Baffa, Raffaele; Silver, Serena; Richon, Victoria; Winter, Christopher; Reddy, Venkat; Gregory, Richard C.
Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2013-10-0124
OAAI
Gao, Qiang; Mechin, Ingrid; Kothari, Nayantara; Guo, Zhuyan; Deng, Gejing; Haas, Kimberly; McManus, Jessica; Hoffmann, Dietmar; Wang, Anlai; Wiederschain, Dmitri; Rocnik, Jennifer; Czechtizky, Werngard; Chen, Xin; McLean, Larry; Arlt, Heike; Harper, David; Liu, Feng; Majid, Tahir; Patel, Vinod; Lengauer, Christoph; Garcia-Echeverria, Carlos; Zhang, Bailin; Cheng, Hong; Dorsch, Marion; Huang, Shih-Min A.
In vitro characterization of spiro-oxindole-based modulators of the MDM2-p53 interaction and their interspecies selectivity.
CANCER RESEARCH
IF16.6
2012-04-012
PRE
Delaisi, Christine; Meaux, Isabelle; Dos-Santos, Odette; Barriere, Cedric; Duffieux, Francis; Hoffmann, Dietmar; Rak, Alexey; Wolfrom, Meredith; Fleche, Frederic; Qing Zhou-Liu; Lalleman, Veronique; Begassat, Francoise; Lowinski, Maryse; Besnard, Sophie; De Chalain, Dominique; Bastien, Helene; Gorge-Bernat, Dimitri; Pannier, Pascal; Ratet, Nathalie; D'Agostino, Stephane; Sanchez, Isabelle; Watters, James; Licht, Stuart; Cheng, Hong; Leopold, Lance; Lengauer, Christoph; Wang, Shaomeng; Garcia-Echeverria, Carlos; Debussche, Laurent

研究方向

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B
Bailin Zhang
H 指数:32论文数:165被引数:6,600
C
Carlos Garcı́a-Echeverrı́a
H 指数:60论文数:297被引数:1.6万
D
Dmitri Wiederschain
H 指数:38论文数:166被引数:6,918
J
Jack Pollard
H 指数:19论文数:130被引数:7,684
M
May Cindhuchao
H 指数:3论文数:14被引数:87
J
Joern Hopke
H 指数:10论文数:23被引数:763
H
Hong Cheng
H 指数:22论文数:66被引数:1,741
C
Christopher Winter
H 指数:24论文数:130被引数:5,056
L
Laurent Debüssche
H 指数:39论文数:263被引数:3,951
C
Chaomei Shi
H 指数:12论文数:49被引数:2,097