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Femtomolar Fab binding affinities to a protein target by alternative CDR residue co-optimization strategies without phage or cell surface display Votsmeier, Christian; Plittersdorf, Hanna; Hesse, Oliver; Scheidig, Andreas; Strerath, Michael; Gritzan, Uwe; Pellengahr, Klaus; Scholz, Peter; Eicker, Andrea; Myszka, David; Coco, Wayne M.; Haupts, Ulrich 分享 收藏
Biophysical Fragment Screening of the β1-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design Christopher, John A.; Brown, Jason; Dore, Andrew S.; Errey, James C.; Koglin, Markus; Marshall, Fiona H.; Myszka, David G.; Rich, Rebecca L.; Tate, Christopher G.; Tehan, Benjamin; Warne, Tony; Congreve, Miles 分享 收藏
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Structure of a Proteasome Pba1-Pba2 Complex IMPLICATIONS FOR PROTEASOME ASSEMBLY, ACTIVATION, AND BIOLOGICAL FUNCTION Stadtmueller, Beth M.; Kish-Trier, Erik; Ferrell, Katherine; Petersen, Charisse N.; Robinson, Howard; Myszka, David G.; Eckert, Debra M.; Formosa, Tim; Hill, Christopher P. 分享 收藏
NPT002: A NOVEL APPROACH FOR TARGETING β-AMYLOID AND TAU AGGREGATES IN ALZHEIMER'S DISEASE Fisher, Richard; Gannon, K.; Krishnan, R.; Tsubery, H.; Lulu, M.; Gartner, M.; Proschitsky, M.; Becker, M.; Wright, J.; Rockenstein, E.; Masliah, E.; Kirschner, D.; Myszka, D.; Solomon, B. 分享 收藏
Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation Kulkarni, Mandar V.; Tettamanzi, M. Cristina; Murphy, James W.; Keeler, Camille; Myszka, David G.; Chayen, Naomi E.; Lolis, Elias J.; Hodsdon, Michael E. 分享 收藏
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Structural basis for ESCRT-III protein autoinhibition Bajorek, Monika; Schubert, Heidi L.; McCullough, John; Langelier, Charles; Eckert, Debra M.; Stubblefield, William-May B.; Uter, Nathan T.; Myszka, David G.; Hill, Christopher P.; Sundquist, Wesley I. 分享 收藏
E2 interaction and dimerization in the crystal structure of TRAF6 TRAF6晶体结构中的E2相互作用和二聚化 Yin, Qian; Lin, Su-Chang; Lamothe, Betty; Lu, Miao; Lo, Yu-Chih; Hura, Gregory; Zheng, Lixin; Rich, Rebecca L.; Campos, Alejandro D.; Myszka, David G.; Lenardo, Michael J.; Darnay, Bryant G.; Wu, Hao 分享 收藏
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Molecular basis for passive immunotherapy of Alzheimer's disease Gardberg, Anna S.; Dice, Lezlee T.; Ou, Susan; Rich, Rebecca L.; Heimbrecht, Elizabeth; Ko, Jan; Wetzel, Ronald; Myszka, David G.; Patterson, Paul H.; Dealwis, Chris 分享 收藏
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