William F. Benedict - Publications, H-index & Citations

William F. Benedict

university of texas system

66H指数

257论文数

1.4W被引数

收录论文 45

发表时间

Deglycosylation Does Not Affect the Cytotoxic Action of Adenoviral Interferon α-Induced Bystander Proteins

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Wang, Desuo; Zhang, Xiaoqiao; Benedict, William F.

MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers

NATURE COMMUNICATIONS

IF15.7

2022-04-04

OAAI

Alhalabi, Omar; Chen, Jianfeng; Zhang, Yuxue; Lu, Yang; Wang, Qi; Ramachandran, Sumankalai; Tidwell, Rebecca Slack; Han, Guangchun; Yan, Xinmiao; Meng, Jieru; Wang, Ruiping; Hoang, Anh G.; Wang, Wei-Lien; Song, Jian; Lopez, Lidia; Andreev-Drakhlin, Alex; Siefker-Radtke, Arlene; Zhang, Xinqiao; Benedict, William F.; Shah, Amishi Y.; Wang, Jennifer; Msaouel, Pavlos; Zhang, Miao; Guo, Charles C.; Czerniak, Bogdan; Behrens, Carmen; Soto, Luisa; Papadimitrakopoulou, Vassiliki; Lewis, Jeff; Rinsurongkawong, Waree; Rinsurongkawong, Vadeerat; Lee, Jack; Roth, Jack; Swisher, Stephen; Wistuba, Ignacio; Heymach, John; Wang, Jing; Campbell, Matthew T.; Efstathiou, Eleni; Titus, Mark; Logothetis, Christopher J.; Ho, Thai H.; Zhang, Jianjun; Wang, Linghua; Gao, Jianjun

MTAP gene deficiency creates vulnerability to anti-folate therapy in urothelial bladder carcinoma

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Chen, Jianfeng; Alhalabi, Omar; Han, Guangchun; Wang, Wei -Lien; Zhang, Xin-Qiao; Song, Jian H.; Lopez, Lidia P.; Ramachandran, Sumankalai; Hoang, Anh G.; Garnett, Tyrone; Campbell, Matthew; Shah, Amishi Y.; Wang, Jennifer; Siefker-Radtke, Arlene O.; Tu, Shi-Ming; Titus, Mark; Guo, Charles C.; Gallick, Gary E.; Efstathiou, Eleni; Benedict, William F.; Logothetis, Christopher J.; Ho, Thai H.; Wang, Linghua; Gao, Jianjun

A Phase I Study of a Tumor-targeted Systemic Nanodelivery System, SGT-94, in Genitourinary Cancers SGT-94，泌尿生殖系统肿瘤靶向全身纳米递送系统的I期研究

MOLECULAR THERAPY

IF12

2016-08-01

OAAI

Siefker-Radtke, Arlene; Zhang, Xin-qiao; Guo, Charles C.; Shen, Yu; Pirollo, Kathleen F.; Sabir, Sharjeel; Leung, Chris; Leong-Wu, Cindy; Ling, Chi-Ming; Chang, Esther H.; Millikan, Randall E.; Benedict, William F.

Systemic administration using targeted gene delivery with SGT-RB94 shows evidence of tumor targeting and anticancer activity: a phase I first-in-man trial

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Siefker-Radtke, Arlene; Zhang, Xin-qiao; Pirollo, Kathleen F.; Chang, Esther H.; Leung, Chris P.; Guo, Charles; Milliken, Randall E.; Benedict, William F.

Phase 1b Trial to Evaluate Tissue Response to a Second Dose of Intravesical Recombinant Adenoviral Interferon α2b Formulated in Syn3 for Failures of Bacillus Calmette-Guerin (BCG) Therapy in Nonmuscle Invasive Bladder Cancer

ANNALS OF SURGICAL ONCOLOGY

IF3.5

2016-07-07

OAAI

Navai, Neema; Benedict, William F.; Zhang, Guangcheng; Abraham, Alice; Ainslie, Nancy; Shah, Jay B.; Grossman, H. Barton; Kamat, Ashish M.; Dinney, Colin P. N.

A Phase I Study of RB94 in Genitourinary Cancers Using a Tumor-Targeted Systemic Nanodelivery System

MOLECULAR THERAPY

IF12

2016-05-01

OAAI

Siefker-Radtke, Arlene; Zhang, Xin-qiao; Guo, Charles C.; Pirollo, Kathleen F.; Leung, Chris P.; Chang, Esther H.; Millikan, Randall E.; Benedict, William F.

Low molecular weight cyclin E is associated with p27-resistant, high-grade, high-stage and invasive bladder cancer

CELL CYCLE

IF3.4

2014-10-28

OAAI

Akli, Said; Zhang, Xin-Qiao; Bondaruk, Jolanta; Tucker, Susan L.; Czerniak, P. Bogdan; Benedict, William F.; Keyomarsi, Khandan

Use of monitoring levels of soluble forms of cytokeratin 18 in the urine of patients with superficial bladder cancer following intravesical Ad-IFNα/Syn3 treatment in a phase 1 study

CANCER GENE THERAPY

IF5

2014-02-07

OAAI

Benedict, W. F.; Fisher, M.; Zhang, X-Q; Yang, Z.; Munsell, M. F.; Dinney, C. N. P.

Phase I Trial of Intravesical Recombinant Adenovirus Mediated Interferon-α2b Formulated in Syn3 for Bacillus Calmette-Guerin Failures in Nonmuscle Invasive Bladder Cancer

JOURNAL OF UROLOGY

IF6.8

2013-09-01

105

OAAI

Dinney, Colin P. N.; Fisher, Mark B.; Navai, Neema; O'Donnell, Michael A.; Cutler, David; Abraham, Alice; Young, Sophia; Hutchins, Beth; Caceres, Maria; Kishnani, Narendra; Sode, George; Cullen, Constance; Zhang, Guangcheng; Grossman, H. Barton; Kamat, Ashish M.; Gonzales, Marshall; Kincaid, Michael; Ainslie, Nancy; Maneval, Daniel C.; Wszolek, Matthew F.; Benedict, William F.

Direct cytotoxicity produced by adenoviral-mediated interferon α gene transfer in interferon-resistant cancer cells involves ER stress and caspase 4 activation

CANCER GENE THERAPY

IF5

2011-06-17

OAAI

Yang, Z.; Zhang, X-Q; Dinney, C. N. P.; Benedict, W. F.

Direct gene transfer of adenoviral-mediated interferon α into human bladder cancer cells but not the bystander factors produced induces endoplasmic reticulum stress-related cytotoxicity

CANCER GENE THERAPY

IF5

2010-12-24

OAAI

Zhang, X-Q; Yang, Z.; Benedict, W. F.

Autophagy is induced by adenoviral-mediated interferon a treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced

CANCER GENE THERAPY

IF5

2010-05-21

OAAI

Zhang, X-Q; Dunner, K., Jr.; Benedict, W. F.

PRELIMINARY RESULTS OF A PHASE I STUDY WITH INTRAVESICAL ADMINISTRATION OF ADENOVIRAL-MEDIATED INTERFERON-α FOR PATIENTS WITH BCG REFRACTORY TRANSITIONAL CELL CARCINOMA OF THE BLADDER

JOURNAL OF UROLOGY

IF6.8

2009-04-01

PREAI

Fisher, Mark B.; Benedict, William F.; Cutler, David L.; Abraham, Alice; Young, Sophia; O'Donnell, Michael A.; Dinney, Colin P.

Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon α: possible use as a surrogate marker

CANCER GENE THERAPY

IF5

2009-02-06

OAAI

Fisher, M. B.; Zhang, X-Q; McConkey, D. J.; Benedict, W. F.

Early RB94-produced cytotoxicity in cancer cells is independent of caspase activation or 50 kb DNA fragmentation

CANCER GENE THERAPY

IF5

2008-07-25

OAAI

Zhou, J.; Zhang, X-Q; Ashoori, F.; McConkey, D. J.; Knowles, M. A.; Dong, L.; Benedict, W. F.

Conditioned medium from Ad-IFN-α-infected bladder cancer and normal urothelial cells is cytotoxic to cancer cells but not normal cells: further evidence for a strong bystander effect

CANCER GENE THERAPY

IF5

2008-07-11

OAAI

Zhang, X.; Dong, L.; Chapman, E.; Benedict, W. F.

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy

LABORATORY INVESTIGATION

IF4.2

2008-07-01

OAAI

Majewski, Tadeusz; Lee, Sangkyou; Jeong, Joon; Yoon, Dong-Sup; Kram, Andrzej; Kim, Mi-Sook; Tuziak, Tomasz; Bondaruk, Jolanta; Lee, Sooyong; Park, Weon-Seo; Tang, Kuang S.; Chung, Woonbok; Shen, Lanlan; Ahmed, Saira S.; Johnston, Dennis A.; Grossman, H. Barton; Dinney, Colin P.; Zhou, Jain-Hua; Harris, R. Alan; Snyder, Carrie; Filipek, Slawomir; Narod, Steven A.; Watson, Patrice; Lynch, Henry T.; Gazdar, Adi; Bar-Eli, Menashe; Wu, Xifeng F.; McConkey, David J.; Baggerly, Keith; Issa, Jean-Pierre; Benedict, William F.; Scherer, Steven E.; Czerniak, Bogdan

Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis p53的Thr18和Ser20磷酸化在Ad-p53-induced凋亡中的作用

NEURO-ONCOLOGY

IF13.4

2008-06-01

OAAI

Nakamizo, Akira; Amano, Toshiyuko; Zhang, Wei; Zhang, Xin-Qiao; Ramdas, Latha; Liu, Ta-Jen; Bekele, B. Nebiyou; Shono, Tadahisa; Sasaki, Tomio; Benedict, William F.; Sawaya, Raymond; Lang, Frederick F.

Tumor-targeting nanocomplex delivery of novel tumor suppressor RB94 chemosensitizes bladder carcinoma cells in vitro and in vivo

CLINICAL CANCER RESEARCH

IF10.2

2008-04-01

OAAI

Pirollo, Kathleen F.; Rait, Antonina; Zhou, Qi; Zhang, Xin-qiao; Zhou, Jain; Kim, Chang-Soo; Benedict, William F.; Chang, Esther H.

研究方向