未登录 Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors Giroud, Maude; Dietzel, Uwe; Anselm, Lilli; Banner, David; Kuglstatter, Andreas; Benz, Jorg; Blanc, Jean-Baptiste; Gaufreteau, Delphine; Liu, Haixia; Lin, Xianfeng; Stich, August; Kuhn, Bernd; Schuler, Franz; Kaiser, Marcel; Brun, Reto; Schirmeister, Tanja; Kisker, Caroline; Diederich, Francois; Haap, Wolfgang 分享 收藏
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A Real-World Perspective on Molecular Design Kuhn, Bernd; Guba, Wolfgang; Hert, Jerome; Banner, David; Bissantz, Caterina; Ceccarelli, Simona; Haap, Wolfgang; Koerner, Matthias; Kuglstatter, Andreas; Lerner, Christian; Mattei, Patrizio; Neidhart, Werner; Pinard, Emmanuel; Rudolph, Markus G.; Schulz-Gasch, Tanja; Wokering, Thomas; Stahl, Martin 分享 收藏
Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses Paquette, Stephane G.; Banner, David; Huang, Stephen S. H.; Almansa, Raquel; Leon, Alberto; Xu, Luoling; Bartoszko, Jessica; Kelvin, David J.; Kelvin, Alyson A. 分享 收藏
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain Schlatter, Daniel; Brack, Simon; Banner, David W.; Batey, Sarah; Benz, Joerg; Bertschinger, Julian; Huber, Walter; Joseph, Catherine; Rufer, Arne C.; van der Klooster, Anita; Weber, Martin; Grabulovski, Dragan; Hennig, Michael 分享 收藏
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Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds Hilpert, Hans; Mauser, Harald; Humm, Roland; Anselm, Lilli; Kuehne, Holger; Hartmann, Guido; Gruener, Sabine; Banner, David W.; Benz, Joerg; Gsell, Bernard; Kuglstatter, Andreas; Stihle, Martine; Thoma, Ralf; Sanchez, Ruben Alvarez; Iding, Hans; Wirz, Beat; Haap, Wolfgang 分享 收藏
Optimization of Triazine Nitriles as Rhodesain Inhibitors: StructureActivity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human CathepsinL Ehmke, Veronika; Winkler, Edwin; Banner, David W.; Haap, Wolfgang; Schweizer, Bernd; Rottmann, Matthias; Kaiser, Marcel; Freymond, Celine; Schirmeister, Tanja; Diederich, Francois 分享 收藏
β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer's Disease Hilpert, Hans; Guba, Wolfgang; Woltering, Thomas J.; Wostl, Wolfgang; Pinard, Emmanuel; Mauser, Harald; Mayweg, Alexander V.; Rogers-Evans, Mark; Humm, Roland; Krummenacher, Daniela; Muser, Thorsten; Schnider, Christian; Jacobsen, Helmut; Ozmen, Laurence; Bergadano, Alessandra; Banner, David W.; Hochstrasser, Remo; Kuglstatter, Andreas; David-Pierson, Pascale; Fischer, Holger; Polara, Alessandra; Narquizian, Robert 分享 收藏
Immunity toward H1N1 influenza hemagglutinin of historical and contemporary strains suggests protection and vaccine failure Huang, Stephen S. H.; Lin, Zhen; Banner, David; Leon, Alberto J.; Paquette, Stephane G.; Rubin, Barry; Rubino, Salvatore; Guan, Yi; Kelvin, David J.; Kelvin, Alyson A. 分享 收藏
Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome Leon, Alberto J.; Banner, David; Xu, Luoling; Ran, Longsi; Peng, Zhiyu; Yi, Kang; Chen, Chao; Xu, Fengping; Huang, Jinrong; Zhao, Zhen; Lin, Zhen; Huang, Stephen H. S.; Fang, Yuan; Kelvin, Alyson A.; Ross, Ted M.; Farooqui, Amber; Kelvin, David J. 分享 收藏
Differential Pathological and Immune Responses in Newly Weaned Ferrets Are Associated with a Mild Clinical Outcome of Pandemic 2009 H1N1 Infection Huang, Stephen S. H.; Banner, David; Degousee, Norbert; Leon, Alberto J.; Xu, Louling; Paquette, Stephane G.; Kanagasabai, Thirumagal; Fang, Yuan; Rubino, Salvatore; Rubin, Barry; Kelvin, David J.; Kelvin, Alyson A. 分享 收藏
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Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism Fange, Yuan; Banner, David; Kelvin, Alyson A.; Huang, Stephen S. H.; Paige, Christopher J.; Corfe, Steven A.; Kane, Kevin P.; Bleackley, R. Chris; Rowe, Thomas; Leon, Alberto J.; Kelvin, David J. 分享 收藏
Molecular Recognition at the Active Site of Factor Xa: Cation-p Interactions, Stacking on Planar Peptide Surfaces, and Replacement of Structural Water Xa因子活性位点的分子识别: 阳离子-p相互作用,在平面肽表面上的堆叠以及结构水的置换 Salonen, Laura M.; Holland, Mareike C.; Kaib, Philip S. J.; Haap, Wolfgang; Benz, Joerg; Mary, Jean-Luc; Kuster, Olivier; Schweizer, W. Bernd; Banner, David W.; Diederich, Francois 分享 收藏
Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments Hardegger, Leo A.; Kuhn, Bernd; Spinnler, Beat; Anselm, Lilli; Ecabert, Robert; Stihle, Martine; Gsell, Bernard; Thoma, Ralf; Diez, Joachim; Benz, Joerg; Plancher, Jean-Marc; Hartmann, Guido; Isshiki, Yoshiaki; Morikami, Kenji; Shimma, Nobuo; Haap, Wolfgang; Banner, David W.; Diederich, Francois 分享 收藏
Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza Almansa, Raquel; Anton, Andres; Ramirez, Paula; Martin-Loeches, Ignacio; Banner, David; Pumarola, Tomas; Xu, Luoling; Blanco, Jesus; Ran, Longsi; Lopez-Campos, Guillermo; Martin-Sanchez, Fernando; Socias, Lorenzo; Loza, Ana; Andaluz, David; Maravi, Enrique; Gordon, Monica; Gallegos, Maria C.; Fernandez, Victoria; Leon, Cristobal; Merino, Pedro; Angeles Marcos, Maria; Gandia, Francisco; Bobillo, Felipe; Resino, Salvador; Ma Eiros, Jose; Castro, Carmen; Mateo, Paula; Gonzalez-Rivera, Milagros; Rello, Jordi; Ortiz de Lejarazu, Raul; Kelvin, David J.; Bermejo-Martin, Jesus F. 分享 收藏
Inflammatory Cytokine Expression Is Associated with Chikungunya Virus Resolution and Symptom Severity Kelvin, Alyson A.; Banner, David; Silvi, Giuliano; Moro, Maria Luisa; Spataro, Nadir; Gaibani, Paolo; Cavrini, Francesca; Pierro, Anna; Rossini, Giada; Cameron, Mark J.; Bermejo-Martin, Jesus F.; Paquette, Stephane G.; Xu, Luoling; Danesh, Ali; Farooqui, Amber; Borghetto, Ilaria; Kelvin, David J.; Sambri, Vittorio; Rubino, Salvatore 分享 收藏
Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions 蛋白质-配体相互作用中卤素键的系统研究 Hardegger, Leo A.; Kuhn, Bernd; Spinnler, Beat; Anselm, Lilli; Ecabert, Robert; Stihle, Martine; Gsell, Bernard; Thoma, Ralf; Diez, Joachim; Benz, Joerg; Plancher, Jean-Marc; Hartmann, Guido; Banner, David W.; Haap, Wolfgang; Diederich, Francois 分享 收藏
Host adaptive immunity deficiency in severe pandemic influenza Bermejo-Martin, Jesus F.; Martin-Loeches, Ignacio; Rello, Jordi; Anton, Andres; Almansa, Raquel; Xu, Luoling; Lopez-Campos, Guillermo; Pumarola, Tomas; Ran, Longsi; Ramirez, Paula; Banner, David; Ng, Derek Cheuk; Socias, Lorenzo; Loza, Ana; Andaluz, David; Maravi, Enrique; Gomez-Sanchez, Maria J.; Gordon, Monica; Gallegos, Maria C.; Fernandez, Victoria; Aldunate, Sara; Leon, Cristobal; Merino, Pedro; Blanco, Jesus; Martin-Sanchez, Fernando; Rico, Lucia; Varillas, David; Iglesias, Veronica; Angeles Marcos, Maria; Gandia, Francisco; Bobillo, Felipe; Nogueira, Begona; Rojo, Silvia; Resino, Salvador; Castro, Carmen; Ortiz de Lejarazu, Raul; Kelvin, David 分享 收藏