Osamu Ichihara - Publications, H-index & Citations

Osamu Ichihara

Hokkaido University

30H指数

99论文数

2.4K被引数

收录论文 12

发表时间

General Theory of Fragment Linking in Molecular Design: Why Fragment Linking Rarely Succeeds and How to Improve Outcomes

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2020-12-29

PREAI

Yu, Haoyu S.; Modugula, Kalyan; Ichihara, Osamu; Kramschuster, Kimberly; Keng, Simon; Abel, Robert; Wang, Lingle

Isolated Polar Amino Acid Residues Modulate Lipid Binding in the Large Hydrophobic Cavity of CD1d

ACS CHEMICAL BIOLOGY

IF3.8

2016-10-04

PREAI

Inuki, Shinsuke; Aiba, Toshihiko; Hirata, Natsumi; Ichihara, Osamu; Yoshidome, Daisuke; Kita, Shunsuke; Maenaka, Katsumi; Fukase, Koichi; Fujimoto, Yukari

Water-Mediated Recognition of Simple Alkyl Chains by Heart-Type Fatty-Acid-Binding Protein

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2014-12-09

OAAI

Matsuoka, Shigeru; Sugiyama, Shigeru; Matsuoka, Daisuke; Hirose, Mika; Lethu, Sebastien; Ano, Hikaru; Hara, Toshiaki; Ichihara, Osamu; Kimura, S. Roy; Murakami, Satoshi; Ishida, Hanako; Mizohata, Eiichi; Inoue, Tsuyoshi; Murata, Michio

The Importance of Hydration Thermodynamics in Fragment-to-Lead Optimization

CHEMMEDCHEM

IF3.4

2014-08-27

PREAI

Ichihara, Osamu; Shimada, Yuzo; Yoshidome, Daisuke

Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2012-08-13

OAAI

Prime, Michael E.; Brookfield, Frederick A.; Courtney, Stephen M.; Gaines, Simon; Marston, Richard W.; Ichihara, Osamu; Li, Marie; Vaidya, Darshan; Williams, Helen; Pedret-Dunn, Anna; Reed, Laura; Schaertl, Sabine; Toledo-Sherman, Leticia; Beconi, Maria; Macdonald, Douglas; Munoz-Sanjuan, Ignacio; Dominguez, Celia; Wityak, John

Discovery and Structure-Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington's Disease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-01-27

PREAI

Prime, Michael E.; Andersen, Ole A.; Barker, John J.; Brooks, Mark A.; Cheng, Robert K. Y.; Toogood-Johnson, Ian; Courtney, Stephen M.; Brookfield, Frederick A.; Yarnold, Christopher J.; Marston, Richard W.; Johnson, Peter D.; Johnsen, Siw F.; Palfrey, Jordan J.; Vaidya, Darshan; Erfan, Sayeh; Ichihara, Osamu; Felicetti, Brunella; Palan, Shilpa; Pedret-Dunn, Anna; Schaertl, Sabine; Sternberger, Ina; Ebneth, Andreas; Scheel, Andreas; Winkler, Dirk; Toledo-Sherman, Leticia; Beconi, Maria; Macdonald, Douglas; Munoz-Sanjuan, Ignacio; Dominguez, Celia; Wityak, John

Prediction of cyclin-dependent kinase 2 inhibitor potency using the fragment molecular orbital method

JOURNAL OF CHEMINFORMATICS

IF5.7

2011-01-10

OAAI

Mazanetz, Michael P.; Ichihara, Osamu; Law, Richard J.; Whittaker, Mark

Discovery of a Novel Hsp90 Inhibitor by Fragment Linking

CHEMMEDCHEM

IF3.4

2010-07-27

PREAI

Barker, John J.; Barker, Oliver; Courtney, Stephen M.; Gardiner, Mihaly; Hesterkamp, Thomas; Ichihara, Osamu; Mather, Owen; Montalbetti, Christian A. G. N.; Mueller, Annett; Varasi, Mario; Whittaker, Mark; Yarnold, Christopher J.

Fragment-based Identification of Hsp90 Inhibitors

CHEMMEDCHEM

IF3.4

2009-05-28

PREAI

Barker, John J.; Barker, Oliver; Boggio, Roberto; Chauhan, Viddhata; Cheng, Robert K. Y.; Corden, Vincent; Courtney, Stephen M.; Edwards, Neil; Falque, Virginie M.; Fusar, Fulvia; Gardiner, Mihaly; Hamelin, Estelle M. N.; Hesterkamp, Thomas; Ichihara, Osamu; Jones, Richard S.; Mather, Owen; Mercurio, Ciro; Minucci, Saverio; Montalbetti, Christian A. G. N.; Mueller, Annett; Patel, Deepti; Phillips, Banu G.; Varasi, Mario; Whittaker, Mark; Winkler, Dirk; Yarnold, Christopher J.

Captured and cross-linked palladium nanoparticles

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2006-04-27

134

PREAI

Cho, Jin Ku; Najman, Romain; Dean, Tony W.; Ichihara, Osamu; Muller, Christophe; Bradley, Mark

Partial reduction of pyridinium salts as a versatile route to dihydropyridones

ORGANIC LETTERS

IF5

2005-01-08

PREAI