Dionisios Vourloumis - Publications, H-index & Citations

Dionisios Vourloumis

National Centre of Scientific Research Demokritos

41H指数

137论文数

5.6K被引数

收录论文 32

发表时间

Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-07-14

OAAI

Vourloumis, Dionisios; Mavridis, Ioannis; Athanasoulis, Alexandros; Temponeras, Ioannis; Koumantou, Despoina; Giastas, Petros; Mpakali, Anastasia; Magrioti, Victoria; Leib, Jacqueline; van Endert, Peter; Stratikos, Efstratios; Papakyriakou, Athanasios

Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2021-02-05

PREAI

Nicolaou, K. C.; Pan, Saiyong; Pulukuri, Kiran K.; Ye, Qiuji; Rigol, Stephan; Erande, Rohan D.; Vourloumis, Dionisios; Nocek, Boguslaw P.; Munneke, Stefan; Lyssikatos, Joseph; Valdiosera, Amanda; Gu, Christine; Lin, Baiwei; Sarvaiaya, Hetal; Trinidad, Jose; Sandoval, Joseph; Lee, Christina; Hammond, Mikhail; Aujay, Monette; Taylor, Nicole; Pysz, Marybeth; Purcell, James W.; Gavrilyuk, Julia

Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-08-27

PREAI

Nicolaou, K. C.; Krieger, Johannes; Murhade, Ganesh M.; Subramanian, Parthasarathi; Dherange, Balu D.; Vourloumis, Dionisios; Munneke, Stefan; Lin, Baiwei; Gu, Christine; Sarvaiaya, Hetal; Sandoval, Joseph; Zhang, Zhaomei; Aujay, Monette; Purcell, James W.; Gavrilyuk, Julia

Exploration of zinc-binding groups for the design of inhibitors for the oxytocinase subfamily of M1 aminopeptidases

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2019-12-01

PREAI

Tsoukalidou, Sofia; Kakou, Magdalini; Mavridis, Ioannis; Koumantou, Despoina; Calderone, Vito; Fragai, Marco; Stratikos, Efstratios; Papakyriakou, Athanasios; Vourloumis, Dionisios

Heterometallic In(III)-Pd(II) Porous Metal-Organic Framework with Square-Octahedron Topology Displaying High CO2 Uptake and Selectivity toward CH4 and N2

INORGANIC CHEMISTRY

IF4.7

2018-06-05

PREAI

Bratsos, Ioannis; Tampaxis, Christos; Spanopoulos, Ioannis; Demitri, Nicola; Charalambopoulou, Georgia; Vourloumis, Dionisios; Steriotis, Theodore A.; Trikalitis, Pantelis N.

Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-01-30

PREAI

Nicolaou, K. C.; Erande, Rohan D.; Yin, Jun; Vourloumis, Dionisios; Aujay, Monette; Sandoval, Joseph; Munneke, Stefan; Gavrilyuk, Julia

Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2017-02-24

OAAI

Mpakali, Anastasia; Giastas, Petros; Deprez-Poulain, Rebecca; Papakyriakou, Athanasios; Koumantou, Despoina; Gealageas, Ronan; Tsoukalidou, Sofia; Vourloumis, Dionisios; Mavridis, Irene M.; Stratikos, Efstratios; Saridakis, Emmanuel

Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-02-01

PREAI

Nicolaou, K. C.; Yun, Jun; Mandal, Debashis; Erande, Rohan D.; Klahn, Philipp; Jin, Michael; Aujay, Monette; Sandoval, Joseph; Gavrilyuk, Julia; Vourloumis, Dionisios

Exceptional gravimetric and volumetric CO2 uptake in a palladated NbO-type MOF utilizing cooperative acidic and basic, metal-CO2 interactions

CHEMICAL COMMUNICATIONS

IF4.2

2016-01-01

PREAI

Spanopoulos, I.; Bratsos, I.; Tampaxis, C.; Vourloumis, D.; Klontzas, E.; Froudakis, G. E.; Charalambopoulou, G.; Steriotis, T. A.; Trikalitis, P. N.

Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs

CHEMMEDCHEM

IF3.4

2015-11-20

PREAI

Nicolaou, Kyriacos C.; Vourloumis, Dionisios; Totokotsopoulos, Sotirios; Papakyriakou, Athanasios; Karsunky, Holger; Fernando, Hanan; Gavrilyuk, Julia; Webb, Damien; Stepan, Antonia F.

3,4-Diaminobenzoic Acid Derivatives as Inhibitors of the Oxytocinase Subfamily of M1 Aminopeptidases with Immune-Regulating Properties

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-01-30

OAAI

Papkyriakou, Athanasios; Zervoudi, Efthalia; Tsoukalidou, Sofia; Mauvais, Francois-Xavier; Sfyroera, Georgia; Mastellos, Dimitrios C.; van Endert, Peter; Theodorakis, Emmanuel A.; Vourloumis, Dionisios; Stratikos, Efstratios

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2011-05-01

PREAI

Androutsopoulos, Vasilis P.; Papakyriakou, Athanasios; Vourloumis, Dionisios; Spandidos, Demetrios A.

Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides

BIOCHEMICAL JOURNAL

IF4.3

2011-03-29

OAAI

Zervoudi, Efthalia; Papakyriakou, Athanasios; Georgiadou, Dimitra; Evnouchidou, Irini; Gajda, Anna; Poreba, Marcin; Salvesen, Guy S.; Drag, Marcin; Hattor, Akira; Swevers, Luc; Vourloumis, Dionisios; Stratikos, Efstratios

Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome P450 CYP1 enzymes

PHARMACOLOGY & THERAPEUTICS

IF12.5

2010-04-01

166

PREAI

Androutsopoulos, Vasilis P.; Papakyriakou, Athanasios; Vourloumis, Dionisios; Tsatsakis, Aristidis M.; Spandidos, Demetrios A.

Discovery of Potent Vascular Endothelial Growth Factor Receptor-2 Inhibitors 发现有效的血管内皮生长因子受体-2抑制剂

CHEMMEDCHEM

IF3.4

2009-12-23

PREAI

Papakyriakou, Athanasios; Katsarou, Maria E.; Belimezi, Maria; Karpusas, Michael; Vourloumis, Dionisios

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2009-01-27

PREAI

Papakyriakou, Athanasios; Vourloumis, Dionisios; Tzortzatou-Stathopoulou, Fotini; Karpusas, Michael

Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-01-19

161

PREAI

Katsarou, Maria E.; Efthimiadou, Eleni K.; Psomas, George; Karaliota, Alexandra; Vourloumis, Dionisios

Total synthesis of oxazole- and cyclopropane-containing epothilone A analogues by the olefin metathesis approach

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2006-01-20

OAAI

Nicolaou, KC; Vallberg, H; King, NP; Roschangar, F; He, Y; Vourloumis, D; Nicolaou, CG

Total synthesis of oxazole- and cyclopropane-containing epothilone B analogues by the macrolactonization approach

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2006-01-20

PREAI

Nicolaou, KC; Sarabia, F; Finlay, MRV; Ninkovic, S; King, NP; Vourloumis, D; He, Y

Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2005-12-01

OAAI

Zhou, YF; Gregor, VE; Sun, ZX; Ayida, BK; Winters, GC; Murphy, D; Simonsen, KB; Vourloumis, D; Fish, S; Froelich, JM; Wall, D; Hermann, T

研究方向