Michelle L. Halls - Publications, H-index & Citations

Michelle L. Halls

Monash University

38H指数

128论文数

5.0K被引数

收录论文 24

发表时间

Hox-C12 coordinates β2-adrenoceptor coupling to a cAMP/calcium feedforward loop to drive invasion in triple-negative breast cancer Hox-C12协调β2-肾上腺素受体偶联至cAMP/钙离子前馈回路以驱动三阴性乳腺癌的侵袭

Science Signaling

IF6.6

2025-08-19

PREAI

Terrance Lam; Bailey Cardwell; Bonan Liu; Cheng Peng; Mia Spark; Sandra Sursock; Cameron J. Nowell; Andrew M. Ellisdon; Aeson Chang; Alastair C. Keen; Erica K. Sloan; Michelle L. Halls

Structure of the human TSC:WIPI3 lysosomal recruitment complex

SCIENCE ADVANCES

IF12.5

2024-11-22

PREAI

Bayly-Jones, Charles; Lupton, Christopher J.; D'Andrea, Laura; Chang, Yong-Gang; Jones, Gareth D.; Steele, Joel R.; Venugopal, Hari; Schittenhelm, Ralf B.; Halls, Michelle L.; Ellisdon, Andrew M.

The application of artificial intelligence to accelerate G protein-coupled receptor drug discovery 人工智能在加速g蛋白偶联受体药物发现中的应用

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2023-05-26

OAAI

Nguyen, Anh T. N.; Nguyen, Diep T. N.; Koh, Huan Yee; Toskov, Jason; MacLean, William; Xu, Andrew; Zhang, Daokun; Webb, Geoffrey I.; May, Lauren T.; Halls, Michelle L.

The application of targeted protein degradation technologies to G protein-coupled receptors

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2023-04-20

OAAI

Keen, Alastair C.; Jorg, Manuela; Halls, Michelle L. L.

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-07-21

OAAI

Chang, Yong-Gang; Lupton, Christopher J.; Bayly-Jones, Charles; Keen, Alastair C.; D'Andrea, Laura; Lucato, Christina M.; Steele, Joel R.; Venugopal, Hari; Schittenhelm, Ralf B.; Whisstock, James C.; Halls, Michelle L.; Ellisdon, Andrew M.

The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-12-09

PREAI

Lupton, Christopher J.; Bayly-Jones, Charles; D'Andrea, Laura; Huang, Cheng; Schittenhelm, Ralf B.; Venugopal, Hari; Whisstock, James C.; Halls, Michelle L.; Ellisdon, Andrew M.

Carvedilol blocks neural regulation of breast cancer progression in vivo and is associated with reduced breast cancer mortality in patients

EUROPEAN JOURNAL OF CANCER

IF7.1

2021-04-01

OAAI

Gillis, Ryan D.; Botteri, Edoardo; Chang, Aeson; Ziegler, Alexandra, I; Chung, Ni-Chun; Pon, Cindy K.; Shackleford, David M.; Andreassen, Bettina K.; Halls, Michelle L.; Baker, Jillian G.; Sloan, Erica K.

Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells 亚型选择性荧光拮抗剂的开发及其在活细胞中人腺苷A1受体研究中的应用

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-03-16

OAAI

Comeo, Eleonora; Trinh, Phuc; Nguyen, Anh T.; Nowell, Cameron J.; Kindon, Nicholas D.; Soave, Mark; Stoddart, Leigh A.; White, Jonathan M.; Hill, Stephen J.; Kellam, Barrie; Halls, Michelle L.; May, Lauren T.; Scammells, Peter J.

Three-dimensional imaging on a chip using optofluidics light-sheet fluorescence microscopy

LAB ON A CHIP

IF5.4

2021-01-01

PREAI

Vargas-Ordaz, Erick J.; Gorelick, Sergey; York, Harrison M.; Liu, Bonan; Halls, Michelle L.; Arumugam, Senthil; Neild, Adrian; de Marco, Alex; Cadarso, Victor J.

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Mai, Quynh N.; Shenoy, Priyank; Quach, Tim; Retamal, Jeffri S.; Gondin, Arisbel B.; Yeatman, Holly R.; Aurelio, Luigi; Conner, Joshua W.; Poole, Daniel P.; Canals, Meritxell; Nowell, Cameron J.; Graham, Bim; Davis, Thomas P.; Briddon, Stephen J.; Hill, Stephen J.; Porter, Christopher J. H.; Bunnett, Nigel W.; Halls, Michelle L.; Veldhuis, Nicholas A.

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-16

OAAI

Jimenez-Vargas, Nestor N.; Gong, Jing; Wisdom, Matthew J.; Jensen, Dane D.; Latorre, Rocco; Hegron, Alan; Teng, Shavonne; DiCello, Jesse J.; Rajasekhar, Pradeep; Veldhuis, Nicholas A.; Carbone, Simona E.; Yu, Yang; Lopez-Lopez, Cintya; Jaramillo-Polanco, Josue; Canals, Meritxell; Reed, David E.; Lomax, Alan E.; Schmidt, Brian L.; Leong, Kam W.; Vanner, Stephen J.; Halls, Michelle L.; Bunnett, Nigel W.; Poole, Daniel P.

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

SCIENCE SIGNALING

IF6.6

2020-03-31

227

OAAI

Gillis, Alexander; Gondin, Arisbel B.; Kliewer, Andrea; Sanchez, Julie; Lim, Herman D.; Alamein, Claudia; Manandhar, Preeti; Santiago, Marina; Fritzwanker, Sebastian; Schmidel, Frank; Katte, Timothy A.; Reekie, Tristan; Grimsey, Natasha L.; Kassiou, Michael; Kellam, Barrie; Krasel, Cornelius; Halls, Michelle L.; Connor, Mark; Lane, J. Robert; Schulz, Stefan; Christie, Macdonald J.; Canals, Meritxell

Ligand-dependent spatiotemporal signaling profiles of the ?-opioid receptor are controlled by distinct protein-interaction networks

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-01

OAAI

Civciristov, Srgjan; Huang, Cheng; Liu, Bonan; Marquez, Elsa A.; Gondin, Arisbel B.; Schittenhelm, Ralf B.; Ellisdon, Andrew M.; Canals, Meritxell; Halls, Michelle L.

Signalling in response to sub-picomolar concentrations of active compounds: Pushing the boundaries of GPCR sensitivity

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2019-04-05

OAAI

Civciristov, Srgjan; Halls, Michelle L.

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor agonists

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-03-01

OAAI

Patil, Rahul; Mohanty, Biswaranjan; Liu, Bonan; Chandrashekaran, Indu R.; Headey, Stephen J.; Williams, Martin L.; Clements, Craig S.; Ilyichova, Olga; Doak, Bradley C.; Genissel, Patrick; Weaver, Richard J.; Vuillard, Laurent; Halls, Michelle L.; Porter, Christopher J. H.; Scanlon, Martin J.

Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations

SCIENCE SIGNALING

IF6.6

2018-10-09

OAAI

Civciristov, Srgjan; Ellisdon, Andrew M.; Suderman, Ryan; Pon, Cindy K.; Evans, Bronwyn A.; Kleifeld, Oded; Charlton, Steven J.; Hlavacek, William S.; Canals, Meritxell; Halls, Michelle L.

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization

SCIENCE SIGNALING

IF6.6

2018-07-17

OAAI

Miess, Elke; Gondin, Arisbel B.; Yousuf, Arsalan; Steinborn, Ralph; Moesslein, Nadja; Yang, Yunshi; Goeldner, Martin; Ruland, Julia G.; Buenemann, Moritz; Krasel, Cornelius; Christie, MacDonald J.; Halls, Michelle L.; Schulz, Stefan; Canals, Meritxell

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-07-16

135

OAAI

Jimenez-Vargas, Nestor N.; Pattison, Luke A.; Zhao, Peishen; Lieu, TinaMarie; Latorre, Rocco; Jensen, Dane D.; Castro, Joel; Aurelio, Luigi; Le, Giang T.; Flynn, Bernard; Herenbrink, Carmen Klein; Yeatman, Holly R.; Edgington-Mitchell, Laura; Porter, Christopher J. H.; Halls, Michelle L.; Canals, Meritxell; Veldhuis, Nicholas A.; Poole, Daniel P.; McLean, Peter; Hicks, Gareth A.; Scheff, Nicole; Chen, Elyssa; Bhattacharya, Aditi; Schmidt, Brian L.; Brierley, Stuart M.; Vanner, Stephen J.; Bunnett, Nigel W.

Genetically Encoded FRET Biosensors to Illuminate Compartmentalised GPCR Signalling

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2018-02-01

PREAI

Halls, Michelle L.; Canals, Meritxell

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission 降钙素基因相关肽受体的内体信号传导介导疼痛传递

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-30

134

OAAI

Yarwood, Rebecca E.; Imlach, Wendy L.; Lieu, TinaMarie; Veldhuis, Nicholas A.; Jensen, Dane D.; Herenbrink, Carmen Klein; Aurelio, Luigi; Cai, Zhijian; Christie, MacDonald J.; Poole, Daniel P.; Porter, Christopher J. H.; McLean, Peter; Hicks, Gareth A.; Geppetti, Pierangelo; Halls, Michelle L.; Canals, Meritxell; Bunnett, Nigel W.

研究方向