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M

Mike Firth

AstraZeneca
H指数:18
被引数:1,812

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荣誉奖项

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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner

表观遗传调节剂以性别依赖的方式将线粒体氧化还原稳态与心脏功能联系起来

NATURE COMMUNICATIONS
IF15.7
2024-03-203
OAAI
ElBeck, Zaher; Hossain, Mohammad Bakhtiar; Siga, Humam; Oskolkov, Nikolay; Karlsson, Fredrik; Lindgren, Julia; Walentinsson, Anna; Koppenhofer, Dominique; Jarvis, Rebecca; Burli, Roland; Jamier, Tanguy; Franssen, Elske; Firth, Mike; Degasperi, Andrea; Bendtsen, Claus; Menzies, Robert I.; Streckfuss-Bomeke, Katrin; Kohlhaas, Michael; Nickel, Alexander G.; Lund, Lars H.; Maack, Christoph; Vegvari, Akos; Betsholtz, Christer
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

一种ii-b型Cas9核酸酶，在体内具有最小化的脱靶和减少的染色体易位

NATURE COMMUNICATIONS
IF15.7
2023-09-063
OAAI
Bestas, Burcu; Wimberger, Sandra; Degtev, Dmitrii; Madsen, Alexandra; Rottner, Antje K.; Karlsson, Fredrik; Naumenko, Sergey; Callahan, Megan; Touza, Julia Liz; Francescatto, Margherita; Moller, Carl Ivar; Badertscher, Lukas; Li, Songyuan; Cerboni, Silvia; Selfjord, Niklas; Ericson, Elke; Gordon, Euan; Firth, Mike; Chylinski, Krzysztof; Taheri-Ghahfarokhi, Amir; Bohlooly-Y, Mohammad; Snowden, Mike; Pangalos, Menelaos; Nuttall, Barrett; Akcakaya, Pinar; Sienski, Grzegorz; Maresca, Marcello
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing
NATURE COMMUNICATIONS
IF15.7
2023-08-1431
OAAI
Wimberger, Sandra; Akrap, Nina; Firth, Mike; Brengdahl, Johan; Engberg, Susanna; Schwinn, Marie K.; Slater, Michael R.; Lundin, Anders; Hsieh, Pei-Pei; Li, Songyuan; Cerboni, Silvia; Sumner, Jonathan; Bestas, Burcu; Schiffthaler, Bastian; Magnusson, Bjoern; Di Castro, Silvio; Iyer, Preeti; Bohlooly-Y, Mohammad; Machleidt, Thomas; Rees, Steve; Engkvist, Ola; Norris, Tyrell; Cadogan, Elaine B.; Forment, Josep V.; Svikovic, Sasa; Akcakaya, Pinar; Taheri-Ghahfarokhi, Amir; Maresca, Marcello
Universal toxin-based selection for precise genome engineering in human cells (vol 12, 497, 2021)
NATURE COMMUNICATIONS
IF15.7
2021-05-100
OAAI
Li, Songyuan; Akrap, Nina; Cerboni, Silvia; Porritt, Michelle J.; Wimberger, Sandra; Lundin, Anders; Moller, Carl; Firth, Mike; Gordon, Euan; Lazovic, Bojana; Sienska, Aleksandra; Pane, Luna Simona; Coelho, Matthew A.; Ciotta, Giovanni; Pellegrini, Giovanni; Sini, Marcella; Xu, Xiufeng; Mitra, Suman; Bohlooly-Y, Mohammad; Taylor, Benjamin J. M.; Sienski, Grzegorz; Maresca, Marcello
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
MOLECULAR THERAPY
IF12
2021-05-0113
OAAI
Zabulica, Mihaela; Srinivasan, Raghuraman C.; Akcakaya, Pinar; Allegri, Gabriella; Bestas, Burcu; Firth, Mike; Hammarstedt, Christina; Jakobsson, Tomas; Jakobsson, Towe; Ellis, Ewa; Jorns, Carl; Makris, Georgios; Scherer, Tanja; Rimann, Nicole; van Zuydam, Natalie R.; Gramignoli, Roberto; Forslow, Anna; Engberg, Susanna; Maresca, Marcello; Rooyackers, Olav; Thony, Beat; Haberle, Johannes; Rosen, Barry; Strom, Stephen C.
Universal toxin-based selection for precise genome engineering in human cells
NATURE COMMUNICATIONS
IF15.7
2021-01-2120
OAAI
Li, Songyuan; Akrap, Nina; Cerboni, Silvia; Porritt, Michelle J.; Wimberger, Sandra; Lundin, Anders; Moller, Carl; Firth, Mike; Gordon, Euan; Lazovic, Bojana; Sienska, Aleksandra; Pane, Luna Simona; Coelho, Matthew A.; Ciotta, Giovanni; Pellegrini, Giovanni; Sini, Marcella; Xu, Xiufeng; Mitra, Suman; Bohlooly-Y, Mohammad; Taylor, Benjamin J. M.; Sienski, Grzegorz; Maresca, Marcello
High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets

用于人iPSC衍生的心肌细胞增殖的高含量表型分析将L型钙通道确定为靶标

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
2019-02-0120
OAAI
Woo, Laura A.; Tkachenko, Svyatoslav; Ding, Mei; Plowright, Alleyn T.; Engkvist, Ola; Andersson, Henrik; Drowley, Lauren; Barrett, Ian; Firth, Mike; Akerblad, Peter; Wolf, Matthew J.; Bekiranov, Stefan; Brautigan, David L.; Wang, Qing-Dong; Saucerman, Jeffrey J.

研究方向

暂未获取到该数据
M
Marcello Maresca
H 指数:26论文数:79被引数:3,129
S
Sandra Wimberger
H 指数:8论文数:17被引数:618
N
Nina Akrap
H 指数:10论文数:36被引数:758
S
Songyuan Li
H 指数:18论文数:50被引数:941
G
Grzegorz Sienski
H 指数:14论文数:26被引数:2,316
M
Mohammad Bohlooly‐Y
H 指数:45论文数:178被引数:1.5万
S
Silvia Cerboni
H 指数:11论文数:28被引数:1,174
E
Euan Gordon
H 指数:20论文数:61被引数:982
P
Pei-Pei Hsieh
H 指数:5论文数:11被引数:183
N
Niek Dekker
H 指数:40论文数:91被引数:6,001