Demian Obregon - Publications, H-index & Citations

Demian Obregon

State University System of Florida

28H指数

67论文数

3.3K被引数

收录论文 14

发表时间

Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage

CELL DEATH & DISEASE

IF9.6

2014-08-14

OAAI

Li, S.; Deng, J.; Hou, H.; Tian, J.; Giunta, B.; Wang, Y.; Sawmiller, D.; Smith, A.; Sanberg, P. R.; Obregon, D.; Mori, T.; Tan, J.

GFAP expression and social deficits in transgenic mice overexpressing human sAPPα

GLIA

IF5.1

2013-07-10

OAAI

Bailey, Antoinette R.; Hou, Huayan; Song, Min; Obregon, Demian F.; Portis, Samantha; Barger, Steven; Shytle, Doug; Stock, Saundra; Mori, Takashi; Sanberg, Paul G.; Murphy, Tanya; Tan, Jun

The immunology of traumatic brain injury: a prime target for Alzheimer's disease prevention

JOURNAL OF NEUROINFLAMMATION

IF10.1

2012-08-01

104

OAAI

Giunta, Brian; Obregon, Demian; Velisetty, Renuka; Sanberg, Paul R.; Borlongan, Cesar V.; Tan, Jun

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation

NATURE COMMUNICATIONS

IF15.7

2012-04-10

156

OAAI

Obregon, Demian; Hou, Huayan; Deng, Juan; Giunta, Brian; Tian, Jun; Darlington, Donna; Shahaduzzaman, Md; Zhu, Yuyuan; Mori, Takashi; Mattson, Mark P.; Tan, Jun

Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α : implications for autism

FASEB JOURNAL

IF4.2

2011-11-15

OAAI

Bailey, Antoinette R.; Hou, Huayan; Obregon, Demian F.; Tian, Jun; Zhu, Yuyan; Zou, Qiang; Nikolic, William V.; Bengtson, Michael; Mori, Takashi; Murphy, Tanya; Tan, Jun

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD)

MOLECULAR NEURODEGENERATION

IF17.5

2011-01-11

OAAI

Salemi, Jon; Obregon, Demian F.; Cobb, Anthony; Reed, Spenser; Sadic, Edin; Jin, Jingji; Fernandez, Francisco; Tan, Jun; Giunta, Brian

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: Implications for HIV-associated neurocognitive disorders

MOLECULAR BRAIN

IF2.9

2011-01-01

OAAI

Giunta, Brian; Ehrhart, Jared; Obregon, Demian F.; Lam, Lucy; Le, Lisa; Jin, JingJi; Fernandez, Francisco; Tan, Jun; Shytle, R. Douglas

EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP

FEBS LETTERS

IF3

2010-09-16

OAAI

Fernandez, Jamie Winderbaum; Rezai-Zadeh, Kavon; Obregon, Demian; Tan, Jun

CD40L disruption enhances Aβ vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation

NEUROBIOLOGY OF DISEASE

IF5.6

2008-02-01

OAAI

Obregon, D.; Hou, H.; Bai, Y.; Nikolic, W. V.; Mori, T.; Luo, Deyan; Zeng, J.; Ehrhart, J.; Fernandez, F.; Morgan, D.; Giunta, B.; Town, T.; Tan, J.

Inflammaging as a prodrome to Alzheimer's disease

JOURNAL OF NEUROINFLAMMATION

IF10.1

2008-01-01

277

OAAI

Giunta, Brian; Fernandez, Francisco; Nikolic, William V.; Obregon, Demian; Rrapo, Elona; Town, Terrence; Tan, Jun

Transcutaneous β-amyloid immunization reduces cerebral β-amyloid deposits without T cell infiltration and microhemorrhage

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2007-02-13

OAAI

Nikolic, William V.; Bai, Yun; Obregon, Demian; Hou, Huayan; Mori, Takashi; Zeng, Jin; Ehrhart, Jared; Shytle, R. Douglas; Giunta, Brian; Morgan, Dave; Town, Terrence; Tan, Jun

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced α-secretase cleavage of amyloid precursor protein

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-06-01

188

OAAI

Obregon, Demian F.; Rezai-Zadeh, Kavon; Bai, Yun; Sun, Nan; Hou, Huayan; Ehrhart, Jared; Zeng, Jin; Mori, Takashi; Arendash, Gary W.; Shytle, Doug; Town, Terrence; Tan, Jun

Proinflammatory and vasoactive effects of Aβ in the cerebrovasculature

ALZHEIMER'S DISEASE: VASCULAR ETIOLOGY AND PATHOLOGY

IF0

2006-01-24

PREAI

Townsend, KP; Obregon, D; Quadros, A; Patel, N; Volmar, C; Paris, D; Mullan, M

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

JOURNAL OF NEUROINFLAMMATION

IF10.1

2005-12-12

333

OAAI

Ehrhart, Jared; Obregon, Demian; Mori, Takashi; Hou, Huayan; Sun, Nan; Bai, Yun; Klein, Thomas; Fernandez, Francisco; Tan, Jun; Shytle, R. Douglas

研究方向