未登录Mapping Dysfunctional Protein-Protein Interactions in Disease绘制疾病中功能失调的蛋白质-蛋白质相互作用
Rodina, Anna; Erdjument-Bromage, Hediye; Monetti, Mara; Li, Zhuoning; Chakrabarty, Souparna; Wang, Shujuan; Digwal, Chander S.; Tuffery, Laura; Panchal, Palak; Sharma, Sahil; Roychowdhury, Tanaya; Neubert, Thomas A.; Chiosis, Gabriela .png)
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收藏Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferationRoychowdhury, Tanaya; McNutt, Seth W.; Pasala, Chiranjeevi; Nguyen, Hieu T.; Thornton, Daniel T.; Sharma, Sahil; Botticelli, Luke; Digwal, Chander S.; Joshi, Suhasini; Yang, Nan; Panchal, Palak; Chakrabarty, Souparna; Bay, Sadik; Markov, Vladimir; Kwong, Charlene; Lisanti, Jeanine; Chung, Sun Young; Ginsberg, Stephen D.; Yan, Pengrong; De Stanchina, Elisa; Corben, Adriana; Modi, Shanu; Alpaugh, Mary L.; Colombo, Giorgio; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Chalkley, Robert J.; Baker, Peter R.; Burlingame, Alma L.; Rodina, Anna; Chiosis, Gabriela; Chu, Feixia 分享 收藏 N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small MoleculesMagni, Andrea; Sciva, Cristiano; Castelli, Matteo; Digwal, Chander S.; Rodina, Anna; Sharma, Sahil; Ochiana, Stefan; Patel, Hardik J.; Shah, Smit; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio 分享 收藏 Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative DisordersBay, Sadik; Digwal, Chander S.; Martin, Ananda M. Rodilla; Sharma, Sahil; Stanisavljevic, Aleksandra; Rodina, Anna; Attaran, Anoosha; Roychowdhury, Tanaya; Parikh, Kamya; Toth, Eugene; Panchal, Palak; Rosiek, Eric; Pasala, Chiranjeevi; Arancio, Ottavio; Fraser, Paul E.; Alldred, Melissa J.; Prado, Marco A. M.; Ginsberg, Stephen D.; Chiosis, Gabriela 分享 收藏 分享 收藏 Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptationRodina, Anna; Xu, Chao; Digwal, Chander S. S.; Joshi, Suhasini; Patel, Yogita; Santhaseela, Anand R. R.; Bay, Sadik; Merugu, Swathi; Alam, Aftab; Yan, Pengrong; Yang, Chenghua; Roychowdhury, Tanaya; Panchal, Palak; Shrestha, Liza; Kang, Yanlong; Sharma, Sahil; Almodovar, Justina; Corben, Adriana; Alpaugh, Mary L. L.; Modi, Shanu; Guzman, Monica L. L.; Fei, Teng; Taldone, Tony; Ginsberg, Stephen D. D.; Erdjument-Bromage, Hediye; Neubert, Thomas A. A.; Manova-Todorova, Katia; Tsou, Meng-Fu Bryan; Young, Jason C. C.; Wang, Tai; Chiosis, Gabriela 分享 收藏 分享 收藏 Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancerJoshi, Suhasini; Gomes, Erica DaGama; Wang, Tai; Corben, Adriana; Taldone, Tony; Gandu, Srinivasa; Xu, Chao; Sharma, Sahil; Buddaseth, Salma; Yan, Pengrong; Chan, Lon Yin L.; Gokce, Askan; Rajasekhar, Vinagolu K.; Shrestha, Lisa; Panchal, Palak; Almodovar, Justina; Digwal, Chander S.; Rodina, Anna; Merugu, Swathi; Pillarsetty, NagaVaraKishore; Miclea, Vlad; Peter, Radu I.; Wang, Wanyan; Ginsberg, Stephen D.; Tang, Laura; Mattar, Marissa; de Stanchina, Elisa; Yu, Kenneth H.; Lowery, Maeve; Grbovic-Huezo, Olivera; O'Reilly, Eileen M.; Janjigian, Yelena; Healey, John H.; Jarnagin, William R.; Allen, Peter J.; Sander, Chris; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Leach, Steven D.; Chiosis, Gabriela 分享 收藏 Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous systemBolaender, Alexander; Zatorska, Danuta; He, Huazhong; Joshi, Suhasini; Sharma, Sahil; Digwal, Chander S.; Patel, Hardik J.; Sun, Weilin; Imber, Brandon S.; Ochiana, Stefan O.; Patel, Maulik R.; Shrestha, Liza; Shah, Smit. K.; Wang, Shuo; Karimov, Rashad; Tao, Hui; Patel, Pallav D.; Martin, Ananda Rodilla; Yan, Pengrong; Panchal, Palak; Almodovar, Justina; Corben, Adriana; Rimner, Andreas; Ginsberg, Stephen D.; Lyashchenko, Serge; Burnazi, Eva; Ku, Anson; Kalidindi, Teja; Lee, Sang Gyu; Grkovski, Milan; Beattie, Bradley J.; Zanzonico, Pat; Lewis, Jason S.; Larson, Steve; Rodina, Anna; Pillarsetty, Nagavarakishore; Tabar, Viviane; Dunphy, Mark P.; Taldone, Tony; Shimizu, Fumiko; Chiosis, Gabriela 分享 收藏 Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a ChaperoneYan, Pengrong; Patel, Hardik J.; Sharma, Sahil; Corben, Adriana; Wang, Tai; Panchal, Palak; Yang, Chenghua; Sun, Weilin; Araujo, Thais L.; Rodina, Anna; Joshi, Suhasini; Robzyk, Kenneth; Gandu, Srinivasa; White, Julie R.; de Stanchina, Elisa; Modi, Shanu; Janjigian, Yelena Y.; Hill, Elizabeth G.; Liu, Bei; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Que, Nanette L. S.; Li, Zihai; Gewirth, Daniel T.; Taldone, Tony; Chiosis, Gabriela 分享 收藏 The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunctionInda, Maria Carmen; Joshi, Suhasini; Wang, Tai; Bolaender, Alexander; Gandu, Srinivasa; Koren, John, III; Che, Alicia Yue; Taldone, Tony; Yan, Pengrong; Sun, Weilin; Uddin, Mohammad; Panchal, Palak; Riolo, Matthew; Shah, Smit; Barlas, Afsar; Xu, Ke; Chan, Lon Yin L.; Gruzinova, Alexandra; Kishinevsky, Sarah; Studer, Lorenz; Fossati, Valentina; Noggle, Scott A.; White, Julie R.; de Stanchina, Elisa; Sequeira, Sonia; Anthoney, Kyle H.; Steele, John W.; Manova-Todorova, Katia; Patil, Sujata; Dunphy, Mark P.; Pillarsetty, NagaVaraKishore; Pereira, Ana C.; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Rodina, Anna; Ginsberg, Stephen D.; Garcia, Natalia De Marco; Luo, Wenjie; Chiosis, Gabriela 分享 收藏 A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and BeyondTaldone, Tony; Wang, Tai; Rodina, Anna; Pillarsetty, Naga Vara Kishore; Digwal, Chander S.; Sharma, Sahil; Yan, Pengrong; Joshi, Suhasini; Pagare, Piyusha P.; Bolaender, Alexander; Roboz, Gail J.; Guzman, Monica L.; Chiosis, Gabriela 分享 收藏 Tumor epichaperome expression using 124I PU-H71 PET (PU-PET) as a biomarker of response for PU-H71 plus nab-paclitaxel in HER2 negative (HER2-) metastatic breast cancer (MBC)Jhaveri, K.; Dunphy, M.; Wang, R.; Comen, E.; Fornier, M.; Moynahan, M. E.; Bromberg, J.; Ma, W.; Patil, S.; Taldone, T.; Rodina, A.; Sterlin, V.; Khoshi, S.; Lewis, J.; Norton, L.; Chiosis, G.; Modi, S. 分享 收藏 分享 收藏 HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neuronsKishinevsky, Sarah; Wang, Tai; Rodina, Anna; Chung, Sun Young; Xu, Chao; Philip, John; Taldone, Tony; Joshi, Suhasini; Alpaugh, Mary L.; Bolaender, Alexander; Gutbier, Simon; Sandhu, Davinder; Fattahi, Faranak; Zimmer, Bastian; Shah, Smit K.; Chang, Elizabeth; Inda, Carmen; Koren, John, III; Saurat, Nathalie G.; Leist, Marcel; Gross, Steven S.; Seshan, Venkatraman E.; Klein, Christine; Tomishima, Mark J.; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Henrickson, Ronald C.; Chiosis, Gabriela; Studer, Lorenz 分享 收藏 Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt LymphomaGiulino-Roth, Lisa; van Besien, Herman J.; Dalton, Tanner; Totonchy, Jennifer E.; Rodina, Anna; Taldone, Tony; Bolaender, Alexander; Erdjument-Bromage, Hediye; Sadek, Jouliana; Chadburn, Amy; Barth, Matthew J.; Dela Cruz, Filemon S.; Rainey, Allison; Kung, Andrew L.; Chiosis, Gabriela; Cesarman, Ethel 分享 收藏 A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 SpeciesZong, Hongliang; Gozman, Alexander; Caldas-Lopes, Eloisi; Taldone, Tony; Sturgill, Eric; Brennan, Sarah; Ochiana, Stefan O.; Gomes-DaGama, Erica M.; Sen, Siddhartha; Rodina, Anna; Koren, John, III; Becker, Michael W.; Rudin, Charles M.; Melnick, Ari; Levine, Ross L.; Roboz, Gail J.; Nimer, Stephen D.; Chiosis, Gabriela; Guzman, Monica L. 分享 收藏 Development of a noninvasive assay to determine drug concentration in tumor during hsp90 inhibitor therapyTaldone, Tony; Pillarsetty, Nagavarakishore; Dunphy, Mark P. S.; Gerecitano, John F.; Caldas-Lopes, Eloisi; Beattie, Brad; Peter, Radu I.; Kang, Yanlong; Rodina, Anna; Yan, Pengrong; Gomes, Erica M. DaGama; Bolaender, Alexander; Pressl, Christina; Punzalan, Blesida; Ku, Anson; Ku, Thomas; Shah, Smit; Uddin, Mohammad; Chen, Mei H.; Santos, Elmer; Koziorowski, Jacek; Corben, Adriana; Modi, Shanu; Jhaveri, Komal; Lin, Oscar; Vakiani, Efsevia; Janjigian, Yelena; Zanzonico, Pat; Hudis, Clifford; Larson, Steven M.; Lewis, Jason S.; Chiosis, Gabriela 分享 收藏 分享 收藏 Development of chemical tools to study the endogenous Hsp70 interactome in malignant cellsRodina, Anna A.; Taldone, Tony; Kang, Yanlong; Patel, Pallav; Koren, John; Yan, Pengrong; Gomes, Erica DaGama; Yang, Chenghua; Patel, Maulik; Shrestha, Liza; Ochiana, Stefan; Maharaj, Ronnie; Gozman, Alexander; Cox, Marc; Erdjument-Bromage, Hediye; Hendrickson, Ronald; Cerchietti, Leandro; Melnick, Ari; Guzman, Monica; Chiosis, Gabriela 分享 收藏 
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