Markku Seppälä - Publications, H-index & Citations

Markku Seppälä

university of helsinki

72H指数

489论文数

1.8W被引数

收录论文 47

发表时间

Biologically Informed Polygenic Scores for Brain Insulin Receptor Network Are Associated with Cardiometabolic Risk Markers and Diabetes in Women 脑胰岛素受体网络的生物学信息多基因评分与女性心脏代谢风险标志物和糖尿病相关

DIABETES & METABOLISM JOURNAL

IF8.5

2024-09-30

OAAI

Selenius, Jannica S.; Silveira, Patricia P.; von Bonsdorff, Mikaela; Lahti, Jari; Koistinen, Hannu; Koistinen, Riitta; Seppaelae, Markku; Eriksson, Johan G.; Wasenius, Niko S.

Decidual glycodelin-A polarizes human monocytes into a decidual macrophage-like phenotype through Siglec-7

JOURNAL OF CELL SCIENCE

IF3.6

2020-07-23

OAAI

Vijayan, Madhavi; Lee, Cheuk-Lun; Wong, Vera H. H.; Wang, Xia; Bai, Kungfeng; Wu, Jian; Koistinen, Hannu; Seppala, Markku; Lee, Kai-Fai; Yeung, William S. B.; Ng, Ernest H. Y.; Chiu, Philip C. N.

Glycodelin-A stimulates the conversion of human peripheral blood CD16-CD56bright NK cell to a decidual NK cell-like phenotype

HUMAN REPRODUCTION

IF6.1

2018-12-28

PREAI

Lee, Cheuk-Lun; Vijayan, Madhavi; Wang, Xia; Lam, Kevin K. W.; Koistinen, Hannu; Seppala, Markku; Li, Raymond H. W.; Ng, Ernest H. Y.; Yeung, William S. B.; Chiu, Philip C. N.

Glycodelin-A Stimulates Interleukin-6 Secretion by Human Monocytes and Macrophages through L-selectin and the Extracellular Signal-regulated Kinase Pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-10-01

OAAI

Lee, Cheuk-Lun; Lam, Eve Y. F.; Lam, Kevin K. W.; Koistinen, Hannu; Seppala, Markku; Ng, Ernest H. Y.; Yeung, William S. B.; Chiu, Philip C. N.

Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line

PLACENTA

IF2.5

2012-09-01

PREAI

Lam, K. K. W.; Pang, R. T. K.; Lee, C. -L.; Koistinen, H.; Seppala, M.; Ho, P. -C.; Yeung, W. S. B.; Chiu, P. C. N.

Glycodelin-A Protein Interacts with Siglec-6 Protein to Suppress Trophoblast Invasiveness by Down-regulating Extracellular Signal-regulated Kinase (ERK)/c-Jun Signaling Pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-10-01

OAAI

Lam, Kevin K. W.; Chiu, Philip C. N.; Lee, Cheuk-Lun; Pang, Ronald T. K.; Leung, Carmen O. N.; Koistinen, Hannu; Seppala, Markku; Ho, Pak-Chung; Yeung, William S. B.

Glycosylation Failure Extends to Glycoproteins in Gestational Diabetes Mellitus Evidence From Reduced α2-6 Sialylation and Impaired Immunomodulatory Activities of Pregnancy-Related Glycodelin-A

DIABETES

IF7.5

2011-02-21

OAAI

Lee, Cheuk-Lun; Chiu, Philip C. N.; Pang, Poh-Choo; Chu, Ivan K.; Lee, Kai-Fai; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Morris, Howard R.; Tissot, Berangere; Panico, Maria; Dell, Anne; Yeung, William S. B.

Differential actions of glycodelin-A on Th-1 and Th-2 cells: a paracrine mechanism that could produce the Th-2 dominant environment during pregnancy

HUMAN REPRODUCTION

IF6.1

2011-01-11

OAAI

Lee, Cheuk-Lun; Chiu, Philip C. N.; Lam, Kevin K. W.; Siu, Siu-On; Chu, Ivan K.; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Lee, Kai-Fai; Yeung, William S. B.

Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx

HUMAN REPRODUCTION

IF6.1

2010-09-14

OAAI

Chiu, Philip C. N.; Wong, Ben S. T.; Lee, Cheuk-Lun; Lam, Kevin K. W.; Chung, Man-Kin; Lee, Kai-Fai; Koistinen, Riitta; Koistinen, Hannu; Gupta, Satish K.; Seppala, Markku; Yeung, William S. B.

Cumulus-associated α2-macroglobulin derivative retains proconceptive glycodelin-C in the human cumulus matrix

HUMAN REPRODUCTION

IF6.1

2009-07-22

OAAI

Chung, Man-Kin; Chiu, Philip C. N.; Lee, Cheuk-Lun; Pang, Ronald T. K.; Ng, E. H. Y.; Lee, Kai-Fai; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Yeung, William S. B.

Glycodelin-A as a modulator of trophoblast invasion

HUMAN REPRODUCTION

IF6.1

2009-06-11

OAAI

Lam, Kevin K. W.; Chiu, Philip C. N.; Chung, Man-Kin; Lee, Cheuk-Lun; Lee, Kai-Fai; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Ho, Pak-Chung; Yeung, William S. B.

Effects of Differential Glycosylation of Glycodelins on Lymphocyte Survival

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2009-05-01

OAAI

Lee, Cheuk-Lun; Pang, Poh-Choo; Yeung, William S. B.; Tissot, Berangere; Panico, Maria; Lao, Terence T. H.; Chu, Ivan K.; Lee, Kai-Fai; Chung, Man-Kin; Lam, Kevin K. W.; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Morris, Howard R.; Dell, Anne; Chiu, Philip C. N.

Glycodelin in reproductive endocrinology and hormone-related cancer

EUROPEAN JOURNAL OF ENDOCRINOLOGY

IF5.2

2009-02-01

PREAI

Seppala, M.; Koistinen, H.; Koistinen, R.; Hautala, L.; Chiu, P. C.; Yeung, W. S.

Glycodelin reduces breast cancer xenograft growth in vivo

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2008-09-12

OAAI

Hautala, Laura C.; Koistinen, Riitta; Seppala, Markku; Butzow, Ralf; Stenman, Ulf-Hakan; Laakkonen, Pirjo; Koistinen, Hannu

In vivo assessment of the human sperm acrosome reaction and the expression of glycodelin-A in human endometrium after levonorgestrel-emergency contraceptive pill administration

HUMAN REPRODUCTION

IF6.1

2007-05-31

PREAI

do Nascimento, Josiane A. A.; Seppala, Markku; Perdigao, Antero; Espejo-Arce, Ximena; Munuce, Maria Jose; Hautala, Laura; Koistinen, Riitta; Andrade, Liliana; Bahamondes, Luis

Glycosylation related actions of glycodelin:: gamete, cumulus cell, immune cell and clinical associations

HUMAN REPRODUCTION UPDATE

IF16.1

2007-02-28

OAAI

Seppala, M.; Koistinen, H.; Koistinen, R.; Chiu, P. C. N.; Yeung, W. S. B.

Cumulus oophorus-associated glycodelin-C displaces sperm-bound glycodelin-A and -F and stimulates spermatozoa-zona pellucida binding

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2007-02-01

OAAI

Chiu, Philip C. N.; Chung, Man-Kin; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Ho, Pak-Chung; Ng, Ernest H. Y.; Lee, Kai-Fai; Yeung, William S. B.

Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding

JOURNAL OF CELL SCIENCE

IF3.6

2007-01-01

OAAI

Chiu, Philip C. N.; Chung, Man-Kin; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Ho, Pak-Chung; Ng, Ernest H. Y.; Lee, Kai-Fai; Yeung, William S. B.

Roles of glycodelin in modulating sperm function

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2006-05-01

PREAI

Yeung, William S. B.; Lee, Kai-Fai; Koistinen, Riitta; Koistinen, Hannu; Seppala, Markku; Ho, P. C.; Chiu, Philip C. N.

Glycodelin reduces carcinoma-associated gene expression in endometrial adenocarcinoma cells

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

IF8.4

2005-12-01

PREAI

Koistinen, H; Seppälä, M; Nagy, B; Tapper, J; Knuutila, S; Koistinen, N

研究方向