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B

Baruch I. Kanner

Hebrew University of Jerusalem
H指数:56
被引数:1.2万
浏览量:0

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Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2023-07-0311
OAAI
Nayak, Smruti Ranjan; Joseph, Deepthi; Hofner, Georg; Dakua, Archishman; Athreya, Arunabh; Wanner, Klaus T.; Kanner, Baruch I.; Penmatsa, Aravind
Both reentrant loops of the sodium-coupled glutamate transporters contain molecular determinants of cation selectivity

钠偶联的谷氨酸转运体的两个折返环均包含阳离子选择性的分子决定因素

JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2018-09-015
OAAI
Silverstein, Nechama; Sliman, Alaa; Stockner, Thomas; Kanner, Baruch I.
SLC6A1 variants identified in epilepsy patients reduce γ-aminobutyric acid transport

在癫痫患者中鉴定出的SLC6A1变体会降低 γ-氨基丁酸的转运

EPILEPSIA
IF6.6
2018-08-2145
OAAI
Mattison, Kari A.; Butler, Kameryn M.; Inglis, George Andrew S.; Dayan, Oshrat; Boussidan, Hanna; Bhambhani, Vikas; Philbrook, Bryan; da Silva, Cristina; Alexander, John J.; Kanner, Baruch I.; Escayg, Andrew
An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2017-03-0116
OAAI
Dayan, Oshrat; Nagarajan, Anu; Shah, Raven; Ben-Yona, Assaf; Forrest, Lucy R.; Kanner, Baruch I.
Electrogenic Steps Associated with Substrate Binding to the Neuronal Glutamate Transporter EAAC1
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2016-05-018
OAAI
Tanui, Rose; Tao, Zhen; Silverstein, Nechama; Kanner, Baruch; Grewer, Christof
Molecular Determinants of Substrate Specificity in Sodium-coupled Glutamate Transporters

钠偶联谷氨酸转运蛋白底物特异性的分子决定因素

JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2015-11-0110
OAAI
Silverstein, Nechama; Ewers, David; Forrest, Lucy R.; Fahlke, Christoph; Kanner, Baruch I.
Cysteine Scanning Mutagenesis of Transmembrane Helix 3 of a Brain Glutamate Transporter Reveals Two Conformationally Sensitive Positions
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2013-01-0112
OAAI
Silverstein, Nechama; Crisman, Thomas J.; Forrest, Lucy R.; Kanner, Baruch I.
Conserved Asparagine Residue Located in Binding Pocket Controls Cation Selectivity and Substrate Interactions in Neuronal Glutamate Transporter
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2012-05-0120
OAAI
Teichman, Shlomit; Qu, Shaogang; Kanner, Baruch I.
A Conserved Aspartate Residue Located at the Extracellular End of the Binding Pocket Controls Cation Interactions in Brain Glutamate Transporters
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2011-12-0122
OAAI
Rosental, Noa; Gameiro, Armanda; Grewer, Christof; Kanner, Baruch I.
Mechanism of Cation Binding to the Glutamate Transporter EAAC1 Probed with Mutation of the Conserved Amino Acid Residue Thr101
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2010-06-0152
OAAI
Tao, Zhen; Rosental, Noa; Kanner, Baruch I.; Gameiro, Armanda; Mwaura, Juddy; Grewer, Christof
Symmetry in the Structure of the Glutamate Transporter GltPh Suggests Conformation of an Alternate State
BIOPHYSICAL JOURNAL
IF3.1
2010-01-010
OAAI
Crisman, Thomas J.; Qu, Shaogang; Kanner, Baruch; Forrest, Lucy
Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2009-12-08139
OAAI
Crisman, Thomas J.; Qu, Shaogang; Kanner, Baruch I.; Forrest, Lucy R.
The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2009-08-2538
OAAI
Teichman, Shlomit; Qu, Shaogang; Kanner, Baruch I.
Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2008-09-0134
OAAI
Qu, Shaogang; Kanner, Baruch I.
The substrates of the γ-aminobutyric acid transporter GAT-1 induce structural rearrangements around the interface of transmembrane domains 1 and 6
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2008-05-0132
OAAI
Rosenberg, Alex; Kanner, Baruch I.
Conformationally sensitive reactivity to permeant sulfhydryl reagents of cysteine residues engineered into helical hairpin 1 of the glutamate transporter GLT-1
MOLECULAR PHARMACOLOGY
IF3
2007-05-0125
PREAI
Shlaifer, Irina; Kanner, Baruch I.
Identification of a lithium interaction site in the γ-aminobutyric acid (GABA) transporter GAT-1
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2006-08-0157
PREAI
Zhou, Yonggang; Zomot, Elia; Kanner, Baruch I.
Proximity of transmembrane domains 1 and 3 of the γ-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2005-07-0128
OAAI
Zomot, E; Zhou, YG; Kanner, BI
Transporter-associated currents in the γ-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2005-05-0117
OAAI
Zhou, YG; Kanner, BI
The aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 is modulated by its Ligands
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2004-04-0144
OAAI
Zhou, YG; Bennett, ER; Kanner, BI

研究方向

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A
Annie Bendahan
H 指数:22论文数:30被引数:3,337
M
Myriam Grunewald
H 指数:19论文数:51被引数:3,213
L
Lucy R. Forrest
H 指数:46论文数:190被引数:7,035
S
Shaogang Qu
H 指数:28论文数:82被引数:2,067
Y
Yonggang Zhou
H 指数:39论文数:149被引数:9,399
M
Michael P. Kavanaugh
H 指数:52论文数:167被引数:1.1万
N
Nechama Silverstein
H 指数:6论文数:12被引数:75
张
张玉民
H 指数:33论文数:274被引数:4,890
T
Thomas J. Crisman
H 指数:11论文数:21被引数:682
C
Christof Grewer
H 指数:35论文数:100被引数:3,363