未登录Self-supervised foundation model captures high-dimensional morphology data from single cell brightfield images
Saini, Kiran; Zhang, Senzeyu; Carelli, Ryan; Jacobs, Kevin B.; Wong-Thai, Amy; Luengo, Cris; Lu, Vivian; Mavropoulos, Anastasia; Jovic, Andreja; Mei, Jeanette; Vollbrecht, Thomas; Boutet, Stephane C.; Salek, Mahyar; Masaeli, Maddison .png)
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收藏Integrating deep learning morphology profiling, cell sorting, and scRNASeq reveals sample diversity and enriched sub-populationsJovic, Andreja; Corona, Christian; Saini, Kiran; Pham, Tiffine; Carelli, Ryan; Lu, Vivian; Zhang, Senzeyu; Boutet, Stephane C.; Masaeli, Maddison 分享 收藏 TREM2 is a radiation-induced target for immunomodulation of tumor-associated macrophages in the prostate cancer tumor microenvironmentVilla-Pulgarin, Janny A.; Chan, Un In; Khani, Francesca; Socciarelli, Fabio; Wu, Jiansheng; Carelli, Ryan; Kraynak, Jeffrey; Formenti, Silvia C.; Marchionni, Luigi; Loda, Massimo; Nagar, Himanshu; Marciscano, Ariel E.; Barbieri, Christopher E. 分享 收藏 Distinct mesenchymal cell states mediate prostate cancer progressionPakula, Hubert; Omar, Mohamed; Carelli, Ryan; Pederzoli, Filippo; Fanelli, Giuseppe Nicolo; Pannellini, Tania; Socciarelli, Fabio; Van Emmenis, Lucie; Rodrigues, Silvia; Fidalgo-Ribeiro, Caroline; Nuzzo, Pier Vitale; Brady, Nicholas J.; Dinalankara, Wikum; Jere, Madhavi; Valencia, Itzel; Saladino, Christopher; Stone, Jason; Unkenholz, Caitlin; Garner, Richard; Alexanderani, Mohammad K.; Khani, Francesca; de Almeida, Francisca Nunes; Abate-Shen, Cory; Greenblatt, Matthew B.; Rickman, David S.; Barbieri, Christopher E.; Robinson, Brian D.; Marchionni, Luigi; Loda, Massimo 分享 收藏 A broad-use deep learning model based on multi-dimensional morphology to identify and characterize tumor cell heterogeneityBoutet, Stephane C.; Mavropoulos, Anastasia; Jovic, Andreja; Mei, Jeanette; Li, Nianzhen; Saini, Kiran; Zhang, Senzeyu; Johnson, Chassidy; Lu, Vivian; Carelli, Ryan; Jacobs, Kevin B.; Salek, Mahyar; Masaeli, Maddison 分享 收藏 Mesenchymal cell populations associated with different stages of prostate cancer progression in mice and humanOmar, Mohamed; Pakula, Hubert; Pederzoli, Filippo; Fanelli, Giuseppe N.; Panellinni, Tania; Carelli, Ryan; Rodrigues, Silvia; Fidalgo-Ribeiro, Caroline; Nuzzo, Pier V.; Emmenis, Lucie V.; Mohammad, Mohammad; Jere, Madhavi; Unkenholz, Caitlin; Rickman, David; Barbieri, Christopher; Robinson, Brian; Marchionni, Luigi; Loda, Massimo 分享 收藏 Deep learning models capture high dimensional features for cell morphology analysisJacobs, Kevin B.; Saini, Kiran; Li, Nianzhen; Zhang, Senzeyu; Carelli, Ryan; Wong-Thai, Amy; Boutet, Stephane C.; Mavropoulos, Anastasia; Jovic, Andreja; Mei, Jeanette; Salek, Mahyar; Masaeli, Maddison 分享 收藏 Multi-dimensional morphology analysis enables identification and label-free enrichment of heterogeneous tumor cell populationsJovic, Andreja; Saini, Kiran; Carelli, Ryan; Pham, Tiffine; Corona, Christian; Mei, Jeanette; Phelan, Michael; Boutet, Stephane C.; Jacobs, Kevn; Kim, Julie; Ray, Manisha; Johnson, Chassidy; Li, Nianzhen; Salek, Mahyar; Masaeli, Maddison; Barnes, Matt; Ramathal, Cyril 分享 收藏 The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune ResponseBerchuck, Jacob E.; Adib, Elio; Abou Alaiwi, Sarah; Dash, Amit K.; Shin, Jin Na; Lowder, Dallin; McColl, Collin; Castro, Patricia; Carelli, Ryan; Benedetti, Elisa; Deng, Jenny; Robertson, Matthew; Baca, Sylvan C.; Bell, Connor; McClure, Heather M.; El Zarif, Talal; Davidsohn, Matthew P.; Lakshminarayanan, Gitanjali; Rizwan, Kinza; Skapura, Darlene G.; Grimm, Sandra L.; Davis, Christel M.; Ehli, Erik A.; Kelleher, Kaitlin M.; Seo, Ji-Heui; Mitsiades, Nicholas; Coarfa, Cristian; Pomerantz, Mark M.; Loda, Massimo; Ittmann, Michael; Freedman, Matthew L.; Kaochar, Salma 分享 收藏 PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesisLinares, Juan F.; Zhang, Xiao; Martinez-Ordonez, Anxo; Duran, Angeles; Kinoshita, Hiroto; Kasashima, Hiroaki; Nakanishi, Naoko; Nakanishi, Yuki; Carelli, Ryan; Cappelli, Luca; Arias, Esperanza; Yashiro, Masakazu; Ohira, Masaichi; Patel, Sanjay; Inghirami, Giorgio; Loda, Massimo; Cuervo, Ana Maria; Diaz-Meco, Maria T.; Moscat, Jorge 分享 收藏 Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancerBrady, Nicholas J.; Bagadion, Alyssa M.; Singh, Richa; Conteduca, Vincenza; Van Emmenis, Lucie; Arceci, Elisa; Pakula, Hubert; Carelli, Ryan; Khani, Francesca; Bakht, Martin; Sigouros, Michael; Bareja, Rohan; Sboner, Andrea; Elemento, Olivier; Tagawa, Scott; Nanus, David M.; Loda, Massimo; Beltran, Himisha; Robinson, Brian; Rickman, David S. 分享 收藏 Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and SerumPenney, Kathryn L.; Tyekucheva, Svitlana; Rosenthal, Jacob; El Fandy, Habiba; Carelli, Ryan; Borgstein, Stephanie; Zadra, Giorgia; Fanelli, Giuseppe Nicolo; Stefanizzi, Lavinia; Giunchi, Francesca; Pomerantz, Mark; Peisch, Samuel; Coulson, Hannah; Lis, Rosina; Kibel, Adam S.; Fiorentino, Michelangelo; Umeton, Renato; Loda, Massimo 分享 收藏 ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate CancerELOVL5是前列腺癌中关键且可靶向的脂肪酸延长酶Centenera, Margaret M.; Scott, Julia S.; Machiels, Jelle; Nassar, Zeyad D.; Miller, Deanna C.; Zinonos, Irene; Dehairs, Jonas; Burvenich, Ingrid J. G.; Zadra, Giorgia; Chetta, Paolo M.; Bango, Clyde; Evergren, Emma; Ryan, Natalie K.; Gillis, Joanna L.; Mah, Chui Yan; Tieu, Terence; Hanson, Adrienne R.; Carelli, Ryan; Bloch, Katarzyna; Panagopoulos, Vasilios; Waelkens, Etienne; Derua, Rita; Williams, Elizabeth D.; Evdokiou, Andreas; Cifuentes-Rius, Anna; Voelcker, Nicolas H.; Mills, Ian G.; Tilley, Wayne D.; Scott, Andrew M.; Loda, Massimo; Selth, Luke A.; Swinnen, Johannes, V; Butler, Lisa M. 分享 收藏 Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9Itkonen, Harri M.; Poulose, Ninu; Steele, Rebecca E.; Martin, Sara Es; Levine, Zebulon G.; Duveau, Damien Y.; Carelli, Ryan; Singh, Reema; Urbanucci, Alfonso; Loda, Massimo; Thomas, Craig J.; Mills, Ian G.; Walker, Suzanne 分享 收藏 
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