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Tumor infiltrating T-cells and loss of expression of SWI/SNF genes in varying stages of clear cell renal cell carcinoma 透明细胞肾细胞癌不同阶段的肿瘤浸润T细胞及SWI/SNF基因表达缺失 Hrizat, Alaa S.; Lin, Ruihe; Eberle-Singh, Jaime; O'Neill, Raymond; Xia, Yan; Testa, Joseph R.; Uzzo, Robert; Mccue, Peter A.; Yang, Haifeng; Li, Li 分享 收藏
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Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities Brca1功能的遗传分离揭示了依赖于突变的pol θ 漏洞 Krais, John J.; Glass, David J.; Chudoba, Ilse; Wang, Yifan; Feng, Wanjuan; Simpson, Dennis; Patel, Pooja; Liu, Zemin; Neumann-Domer, Ryan; Betsch, Robert G.; Bernhardy, Andrea J.; Bradbury, Alice M.; Conger, Jason; Yueh, Wei-Ting; Nacson, Joseph; Pomerantz, Richard T.; Gupta, Gaorav P.; Testa, Joseph R.; Johnson, Neil 分享 收藏
Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma 炎症是石棉诱导的恶性间皮瘤的化学预防靶标 Kadariya, Yuwaraj; Sementino, Eleonora; Shrestha, Ujjawal; Gorman, Greg; White, Jonathan M.; Ross, Eric A.; Clapper, Margie L.; Neamati, Nouri; Miller, Mark Steven; Testa, Joseph R. 分享 收藏
BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma Langbein, Lauren E.; El Hajjar, Rayan; He, Shen; Sementino, Eleonora; Zhong, Zhijiu; Jiang, Wei; Leiby, Benjamin E.; Li, Li; Uzzo, Robert G.; Testa, Joseph R.; Yang, Haifeng 分享 收藏
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells 药物外排泵MDR1促进癌细胞对PROTACs的内在和获得性耐药 Kurimchak, Alison M.; Herrera-Montavez, Carlos; Montserrat-Sangra, Sara; Araiza-Olivera, Daniela; Hu, Jianping; Neumann-Domer, Ryan; Kuruvilla, Mathew; Bellacosa, Alfonso; Testa, Joseph R.; Jin, Jian; Duncan, James S. 分享 收藏
Thymine DNA glycosylase as a novel target for melanoma (vol 38, pg 3710, 2019) Mancuso, Pietro; Tricarico, Rossella; Bhattacharjee, Vikram; Cosentino, Laura; Kadariya, Yuwaraj; Jelinek, Jaroslav; Nicolas, Emmanuelle; Einarson, Margret; Beeharry, Neil; Devarajan, Karthik; Katz, Richard A.; Dorjsuren, Dorjbal G.; Sun, Hongmao; Simeonov, Anton; Giordano, Antonio; Testa, Joseph R.; Davidson, Guillaume; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy J.; Bellacosa, Alfonso 分享 收藏
Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase Peng, Hongzhuang; Cassel, Joel; McCracken, Daniel S.; Prokop, Jeremy W.; Sementino, Eleonora; Cheung, Mitchell; Collop, Paul R.; Polo, Alexander; Joshi, Surbhi; Mandell, Jacob P.; Ayyanathan, Kasirajan; Hinds, David; Malkowicz, S. Bruce; Harbour, J. William; Bowcock, Anne M.; Salvino, Joseph; Kennedy, Eileen J.; Testa, Joseph R.; Rauscher, Frank J., III 分享 收藏
Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma RIPK3的体细胞表观遗传沉默可灭活坏死性凋亡并有助于恶性间皮瘤的化学抗性 Tan, Yinfei; Sementino, Eleonora; Cheung, Mitchell; Peri, Suraj; Menges, Craig W.; Kukuyan, Anna-Mariya; Zhang, Ting; Khazak, Vladimir; Fox, Lauren A.; Ross, Eric A.; Ramanathan, Suresh; Jhanwar, Suresh C.; Flores, Raja M.; Balachandran, Siddharth; Testa, Joseph R. 分享 收藏
Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis Gary, Joy M.; Simmons, John K.; Xu, Jinfei; Zhang, Shuling; Peat, Tyler J.; Watson, Nicholas; Gamache, Benjamin J.; Zhang, Ke; Kovalchuk, Alexander L.; Michalowski, Aleksandra M.; Chen, Jin-Qiu; Thaiwong, Tuddow; Kiupel, Matti; Gaikwad, Snehal; Etienne, Maudeline; Simpson, R. Mark; Dubois, Wendy; Testa, Joseph R.; Mock, Beverly A. 分享 收藏
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PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth Cai, Weijia; Su, Liya; Liao, Lili; Liu, Zongzhi Z.; Langbein, Lauren; Dulaimi, Essel; Testa, Joseph R.; Uzzo, Robert G.; Zhong, Zhijiu; Jiang, Wei; Yan, Qin; Zhang, Qing; Yang, Haifeng 分享 收藏
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Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models Kukuyan, Anna-Mariya; Sementino, Eleonora; Kadariya, Yuwaraj; Menges, Craig W.; Cheung, Mitchell; Tan, Yinfei; Cai, Kathy Q.; Slifker, Michael J.; Peri, Suraj; Klein-Szanto, Andres J.; Rauscher, Frank J., III; Testa, Joseph R. 分享 收藏
NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma Pei, Jianming; Cooper, Harry; Flieder, Douglas B.; Talarchek, Jacqueline N.; Al-Saleem, Tahseen; Uzzo, Robert G.; Dulaimi, Essel; Patchefsky, Arthur S.; Testa, Joseph R.; Wei, Shuanzeng 分享 收藏
Thymine DNA glycosylase as a novel target for melanoma Mancuso, Pietro; Tricarico, Rossella; Bhattacharjee, Vikram; Cosentino, Laura; Kadariya, Yuwaraj; Jelinek, Jaroslav; Nicolas, Emmanuelle; Einarson, Margret; Beeharry, Neil; Devarajan, Karthik; Katz, Richard A.; Dorjsuren, Dorjbal G.; Sun, Hongmao; Simeonov, Anton; Giordano, Antonio; Testa, Joseph R.; Davidson, Guillaume; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy J.; Bellacosa, Alfonso 分享 收藏
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Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations Kadariya, Yuwaraj; Cheung, Mitchell; Xu, Jinfei; Pei, Jianming; Sementino, Eleonora; Menges, Craig W.; Cai, Kathy Q.; Rauscher, Frank J.; Klein-Szanto, Andres J.; Testa, Joseph R. 分享 收藏
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