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K

Kumari G. Lokugamage

University of Texas Medical Branch

35H指数
93论文数
10.0K被引数
收录论文 26
发表时间
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Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection奥密克戎变异株的功能缺失突变降低了刺突蛋白表达并减弱了SARS-CoV-2感染
errNature Communications
IF15.7
err2026-08-12
err0
errOAAI
errMichelle N. Vu; R. Elias Alvarado; Dorothea R. Morris; Kumari G. Lokugamage; Yiyang Zhou; Angelica L. Morgan; Yani P. Ahearn; Nicholas C. Hazell; Leah K. Estes; Alyssa M. McLeland; Craig Schindewolf; Jessica A. Plante; William M. Meyers; Jordan T. Murray; Patricia A. Crocquet-Valdes; Scott C. Weaver; Mehul S. Suthar; David H. Walker; William K. Russell; Andrew L. Routh; Haitao Hu; Kenneth S. Plante; Vineet D. Menachery
err分享
err收藏
Key residues in SARS-CoV-2 NSP3 hypervariable region are necessary to modulate early stress granule activitySARS-CoV-2 NSP3高变区中的关键残基对早期应激颗粒活性的调控是必要的
errJournal of Virology
IF3.8
err2026-01-01
err0
PREAI
errAlvarado, R. Elias; Lokugamage, Kumari G.; Garvanska, Dimitriya; Estes, Leah K.; Ahearn, Yani; McLeland, Alyssa M.; Moayyed, Arian; Chen, Jennifer; Mendez, Blanca Lopez; Plante, Jessica A.; Plante, Kenneth S.; Johnson, Bryan A.; Nilsson, Jakob; Menachery, Vineet D.
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err收藏
SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitnessSARS-CoV-2 EndoU-核糖核酸酶调控RNA重组并影响病毒适应性
errNature Communications
IF15.7
err2025-12-02
err0
errOAAI
errYiyang Zhou; Yani P. Ahearn; Kumari G. Lokugamage; Angelica L. Morgan; R. Elias Alvarado; Leah K. Estes; William M. Meyers; Alyssa M. McLeland; Jordan T. Murray; Joseph R. Rouse; Meenakshi Kar; Mehul S. Suthar; David H. Walker; Bryan A. Johnson; Andrew L. Routh; Vineet D. Menachery
err分享
err收藏
Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidationSARS-CoV-2核衣壳中的变异突变G215C通过改变基因组衣壳化增强病毒感染。
errPLOS BIOLOGY
IF7.2
err2025-04-29
err0
errOAAI
errKubinski, Hannah C.; Despres, Hannah W.; Johnson, Bryan A.; Schmidt, Madaline M.; Jaffrani, Sara A.; Turner, Allyson H.; Fanuele, Conor D.; Mills, Margaret G.; Lokugamage, Kumari G.; Dumas, Caroline M.; Shirley, David J.; Estes, Leah K.; Pekosz, Andrew; Crothers, Jessica W.; Roychoudhury, Pavitra; Greninger, Alexander L.; Jerome, Keith R.; Di Genova, Bruno Martorelli; Walker, David H.; Ballif, Bryan A.; Ladinsky, Mark S.; Bjorkman, Pamela J.; Menachery, Vineet D.; Bruce, Emily A.
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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
errCELL REPORTS
IF6.9
err2024-03-01
err12
errOAAI
errYang, Zemin; Johnson, Bryan A.; Meliopoulos, Victoria A.; Ju, Xiaohui; Zhang, Peipei; Hughes, Michael P.; Wu, Jinjun; Koreski, Kaitlin P.; Clary, Jemma E.; Chang, Ti-Cheng; Wu, Gang; Hixon, Jeff; Duffner, Jay; Wong, Kathy; Lemieux, Rene; Lokugamage, Kumari G.; Alvarado, R. Elias; Crocquet-Valdes, Patricia A.; Walker, David H.; Plante, Kenneth S.; Plante, Jessica A.; Weaver, Scott C.; Kim, Hong Joo; Meyers, Rachel; Schultz-Cherry, Stacey; Ding, Qiang; Menachery, Vineet D.; Taylor, J. Paul
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err收藏
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactionsSARS-CoV-2的NSP3蛋白结合脆性X智力低下蛋白以破坏UBAP2L相互作用
errEMBO REPORTS
IF6.2
err2024-01-02
err3
errOAAI
errGarvanska, Dimitriya H.; Alvarado, R. Elias; Mundt, Filip Oskar; Lindqvist, Richard; Duel, Josephine Kerzel; Coscia, Fabian; Nilsson, Emma; Lokugamage, Kumari; Johnson, Bryan A.; Plante, Jessica A.; Morris, Dorothea R.; Vu, Michelle N.; Estes, Leah K.; McLeland, Alyssa M.; Walker, Jordyn; Crocquet-Valdes, Patricia A.; Mendez, Blanca Lopez; Plante, Kenneth S.; Walker, David H.; Weisser, Melanie Bianca; Overby, Anna K.; Mann, Matthias; Menachery, Vineet D.; Nilsson, Jakob
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err收藏
SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3
errJOURNAL OF VIROLOGY
IF3.8
err2023-02-28
err22
errOAAI
errSchindewolf, Craig; Lokugamage, Kumari; Vu, Michelle N.; Johnson, Bryan A.; Scharton, Dionna; Plante, Jessica A.; Kalveram, Birte; Crocquet-Valdes, Patricia A.; Sotcheff, Stephanea; Jaworski, Elizabeth; Alvarado, Rojelio E.; Debbink, Kari; Daugherty, Matthew D.; Weaver, Scott C.; Routh, Andrew L.; Walker, David H.; Plante, Kenneth S.; Menachery, Vineet D.
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err收藏
QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-07-26
err20
errOAAI
errVu, Michelle N.; Lokugamage, Kumari G.; Plante, Jessica A.; Scharton, Dionna; Bailey, Aaron O.; Sotcheff, Stephanea; Swetnam, Daniele M.; Johnson, Bryan A.; Schindewolf, Craig; Alvarado, R. Elias; Crocquet-Valdes, Patricia A.; Debbink, Kari; Weaver, Scott C.; Walker, David H.; Russell, William K.; Routh, Andrew L.; Plante, Kenneth S.; Menachery, Vineet D.
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LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
errCELL REPORTS
IF6.9
err2022-05-01
err281
errOAAI
errWestendorf, Kathryn; Zentelis, Stefanie; Wang, Lingshu; Foster, Denisa; Vaillancourt, Peter; Wiggin, Matthew; Lovett, Erica; van der Lee, Robin; Hendle, Joerg; Pustilnik, Anna; Sauder, J. Michael; Kraft, Lucas; Hwang, Yuri; Siegel, Robert W.; Chen, Jinbiao; Heinz, Beverly A.; Higgs, Richard E.; Kallewaard, Nicole L.; Jepson, Kevin; Goya, Rodrigo; Smith, Maia A.; Collins, David W.; Pellacani, Davide; Xiang, Ping; de Puyraimond, Valentine; Ricicova, Marketa; Devorkin, Lindsay; Pritchard, Caitlin; O'Neill, Aoise; Dalal, Kush; Panwar, Pankaj; Dhupar, Harveer; Garces, Fabian A.; Cohen, Courtney A.; Dye, John M.; Huie, Kathleen E.; V. Badger, Catherine; Kobasa, Darwyn; Audet, Jonathan; Freitas, Joshua J.; Hassanali, Saleema; Hughes, Ina; Munoz, Luis; Palma, Holly C.; Ramamurthy, Bharathi; Cross, Robert W.; Geisbert, Thomas W.; Menachery, Vineet; Lokugamage, Kumari; Borisevich, Viktoriya; Lanz, Iliana; Anderson, Lisa; Sipahimalani, Payal; Corbett, Kizzmekia S.; Yang, Eun Sung; Zhang, Yi; Shi, Wei; Zhou, Tongqing; Choe, Misook; Misasi, John; Kwong, Peter D.; Sullivan, Nancy J.; Graham, Barney S.; Fernandez, Tara L.; Hansen, Carl L.; Falconer, Ester; Mascola, John R.; Jones, Bryan E.; Barnhart, Bryan C.
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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19 (vol 11, 5214, 2020)
errNATURE COMMUNICATIONS
IF15.7
err2021-06-21
err1
errOAAI
errXie, Xuping; Muruato, Antonio E.; Zhang, Xianwen; Lokugamage, Kumari G.; Fontes-Garfias, Camila R.; Zou, Jing; Liu, Jianying; Ren, Ping; Balakrishnan, Mini; Cihlar, Tomas; Tseng, Chien-Te K.; Makino, Shinji; Menachery, Vineet D.; Bilello, John P.; Shi, Pei-Yong
err分享
err收藏
Engineering SARS-CoV-2 using a reverse genetic system
errNATURE PROTOCOLS
IF16
err2021-01-29
err113
errOAAI
errXie, Xuping; Lokugamage, Kumari G.; Zhang, Xianwen; Vu, Michelle N.; Muruato, Antonio E.; Menachery, Vineet D.; Shi, Pei-Yong
err分享
err收藏
Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoVI型干扰素易感性区分SARS-CoV-2和传染性非典型肺炎
errJOURNAL OF VIROLOGY
IF3.8
err2020-11-09
err281
errOAAI
errLokugamage, Kumari G.; Hage, Adam; de Vries, Maren; Valero-Jimenez, Ana M.; Schindewolf, Craig; Dittmann, Meike; Rajsbaum, Ricardo; Menachery, Vineet D.
err分享
err收藏
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
errNATURE COMMUNICATIONS
IF15.7
err2020-10-15
err109
errOAAI
errXie, Xuping; Muruato, Antonio E.; Zhang, Xianwen; Lokugamage, Kumari G.; Fontes-Garfias, Camila R.; Zou, Jing; Liu, Jianying; Ren, Ping; Balakrishnan, Mini; Cihlar, Tomas; Tseng, Chien-Te K.; Makino, Shinji; Menachery, Vineet D.; Bilello, John P.; Shi, Pei-Yong
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err收藏
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States
errEMERGING INFECTIOUS DISEASES
IF6.6
err2020-06-01
err401
errOAAI
errHarcourt, Jennifer; Tamin, Azaibi; Lu, Xiaoyan; Kamili, Shifaq; Sakthivel, Senthil K.; Murray, Janna; Queen, Krista; Tao, Ying; Paden, Clinton R.; Zhang, Jing; Li, Yan; Uehara, Anna; Wang, Haibin; Goldsmith, Cynthia; Bullock, Hannah A.; Wang, Lijuan; Whitaker, Brett; Lynch, Brian; Gautam, Rashi; Schindewolf, Craig; Lokugamage, Kumari G.; Scharton, Dionna; Plante, Jessica A.; Mirchandani, Divya; Widen, Steven G.; Narayanan, Krishna; Makino, Shinji; Ksiazek, Thomas G.; Plante, Kenneth S.; Weaver, Scott C.; Lindstrom, Stephen; Tong, Suxiang; Menachery, Vineet D.; Thornburg, Natalie J.
err分享
err收藏
Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway冠状病毒，细胞质RNA病毒和无义介导的mRNA衰变途径之间的相互作用
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2018-10-08
err73
errOAAI
errWada, Masami; Lokugamage, Kumari G.; Nakagawa, Keisuke; Narayanan, Krishna; Makino, Shinji
err分享
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Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin
errJOURNAL OF VIROLOGY
IF3.8
err2015-11-01
err133
errOAAI
errLokugamage, Kumari G.; Narayanan, Krishna; Nakagawa, Keisuke; Terasaki, Kaori; Ramirez, Sydney I.; Tseng, Chien-Te K.; Makino, Shinji
err分享
err收藏
Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation
errJOURNAL OF VIROLOGY
IF3.8
err2012-12-15
err165
errOAAI
errLokugamage, Kumari G.; Narayanan, Krishna; Huang, Cheng; Makino, Shinji
err分享
err收藏
SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
errPLOS PATHOGENS
IF4.9
err2011-12-08
err285
errOAAI
errHuang, Cheng; Lokugamage, Kumari G.; Rozovics, Janet M.; Narayanan, Krishna; Semler, Bert L.; Makino, Shinji
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Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Protein Suppresses Protein Translation in Mammalian Cells and in Cell-Free HeLa Cell Extracts but Not in Rabbit Reticulocyte Lysate
errJOURNAL OF VIROLOGY
IF3.8
err2011-01-01
err81
errOAAI
errHuang, Cheng; Lokugamage, Kumari G.; Rozovics, Janet M.; Narayanan, Krishna; Semler, Bert L.; Makino, Shinji
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err收藏
Mechanism of tripartite RNA genome packaging in Rift Valley fever virus
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2010-12-27
err49
errOAAI
errTerasaki, Kaori; Murakami, Shin; Lokugamage, Kumari G.; Makino, Shinji
err分享
err收藏

研究方向

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