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收藏Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations大规模遗传分析揭示了哺乳动物mtDNA异质性动态和方差随寿命和世代的增加
Burgstaller, Joerg P.; Kolbe, Thomas; Havlicek, Vitezslav; Hembach, Stephanie; Poulton, Joanna; Pialek, Jaroslav; Steinborn, Ralf; Ruelicke, Thomas; Brem, Gottfried; Jones, Nick S.; Johnston, Iain G.
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收藏Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism
Johnston, Iain G.; Burgstaller, Joerg P.; Havlicek, Vitezslav; Kolbe, Thomas; Ruelicke, Thomas; Brem, Gottfried; Poulton, Jo; Jones, Nick S.
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收藏mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage
Burgstaller, Joerg Patrick; Johnston, Iain G.; Jones, Nick S.; Albrechtova, Jana; Kolbe, Thomas; Vogl, Claus; Futschik, Andreas; Mayrhofer, Corina; Klein, Dieter; Sabitzer, Sonja; Blattner, Mirjam; Guelly, Christian; Poulton, Joanna; Ruelicke, Thomas; Pialek, Jaroslav; Steinborn, Ralf; Brem, Gottfried
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