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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy Guelen, Lars; Fischmann, Thierry O.; Wong, Jerelyn; Mauze, Smita; Guadagnoli, Marco; Babala, Nikolina; Wagenaars, Jozef; Juan, Veronica; Rosen, David; Prosise, Winnie; Habraken, Maurice; Lodewijks, Imke; Gu, Danling; Stammen-Vogelzangs, Judith; Yu, Ying; Baker, Jeanne; Hulsik, David Lutje; Driessen-Engels, Lilian; Malashock, Dan; Kreijtz, Joost; Bertens, Astrid; de Vries, Evert; Bovens, Astrid; Bramer, Arne; Zhang, Yiwei; Wnek, Richard; Troth, Sean; Chartash, Elliot; Dobrenkov, Konstantin; Sadekova, Svetlana; van Elsas, Andrea; Cheung, Jason K.; Fayadat-Dilman, Laurence; Borst, Jannie; Beebe, Amy M.; Van Eenennaam, Hans 分享 收藏
Characterization and Modeling of Reversible Antibody Self-Association Provide Insights into Behavior, Prediction, and Correction Mieczkowski, Carl; Cheng, Alan; Fischmann, Thierry; Hsieh, Mark; Baker, Jeanne; Uchida, Makiko; Raghunathan, Gopalan; Strickland, Corey; Fayadat-Dilman, Laurence 分享 收藏
Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies Mieczkowski, Carl; Bahmanjah, Soheila; Yu, Yao; Baker, Jeanne; Raghunathan, Gopalan; Tomazela, Daniela; Hsieh, Mark; McCoy, Mark; Strickland, Corey; Fayadat-Dilman, Laurence 分享 收藏
Predicting Antibody Developability Profiles Through Early Stage Discovery Screening Bailly, Marc; Mieczkowski, Carl; Juan, Veronica; Metwally, Essam; Tomazela, Daniela; Baker, Jeanne; Uchida, Makiko; Kofman, Ester; Raoufi, Fahimeh; Motlagh, Soha; Yu, Yao; Park, Jihea; Raghava, Smita; Welsh, John; Rauscher, Michael; Raghunathan, Gopalan; Hsieh, Mark; Chen, Yi-Ling; Nguyen, Hang Thu; Nguyen, Nhung; Cipriano, Dan; Fayadat-Dilman, Laurence 分享 收藏
Antagonism of the co-inhibitory receptor BTLA enhances efficacy of anti-PD-1 treatment in murine syngeneic tumor models Miselis, Nathan R.; Linn, Douglas; Restaino, Clifford; Baral, Toya; Xia, Jane; Ueda, Roanna; Sawant, Anandi; Baker, Jeanne; Raghunathan, Gopalan; Wang, Xinzhong; Bowman, Edward; Sukumar, Selvakumar 分享 收藏
Selective and Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation in Rat Brain 选择性和脑渗透性Polo样激酶-2 (Plk-2) 抑制剂，可减少大鼠脑中的突触核蛋白磷酸化 Aubele, Danielle L.; Hom, Roy K.; Adler, Marc; Galemmo, Robert A., Jr.; Bowers, Simeon; Truong, Anh P.; Pan, Hu; Beroza, Paul; Neitz, R. Jeffrey; Yao, Nanhua; Lin, May; Tonn, George; Zhang, Heather; Bova, Michael P.; Ren, Zhao; Tam, Danny; Ruslim, Lany; Baker, Jeanne; Diep, Linnea; Fitzgerald, Kent; Hoffman, Jennifer; Motter, Ruth; Fauss, Donald; Tanaka, Pearl; Dappen, Michael; Jagodzinski, Jacek; Chan, Wayman; Konradi, Andrei W.; Latimer, Lee; Zhu, Yong L.; Sham, Hing L.; Anderson, John P.; Bergeron, Marcelle; Artis, Dean R. 分享 收藏
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases Riley, B. E.; Lougheed, J. C.; Callaway, K.; Velasquez, M.; Brecht, E.; Nguyen, L.; Shaler, T.; Walker, D.; Yang, Y.; Regnstrom, K.; Diep, L.; Zhang, Z.; Chiou, S.; Bova, M.; Artis, D. R.; Yao, N.; Baker, J.; Yednock, T.; Johnston, J. A. 分享 收藏
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease Basi, Guriqbal S.; Hemphill, Susanna; Brigham, Elizabeth F.; Liao, Anna; Aubele, Danielle L.; Baker, Jeanne; Barbour, Robin; Bova, Michael; Chen, Xiao-Hua; Dappen, Michael S.; Eichenbaum, Tovah; Goldbach, Erich; Hawkinson, Jon; Lawler-Herbold, Rose; Hu, Kang; Hui, Terence; Jagodzinski, Jacek J.; Keim, Pamela S.; Kholodenko, Dora; Latimer, Lee H.; Lee, Mike; Marugg, Jennifer; Mattson, Matthew N.; McCauley, Scott; Miller, James L.; Motter, Ruth; Mutter, Linda; Neitzel, Martin L.; Ni, Huifang; Lan Nguyen; Quinn, Kevin; Ruslim, Lany; Semko, Christopher M.; Shapiro, Paul; Smith, Jenifer; Soriano, Ferdie; Szoke, Balazs; Tanaka, Kevin; Tang, Pearl; Tucker, John A.; Ye, Xiacong Michael; Yu, Mei; Wu, Jing; Xu, Ying-zi; Garofalo, Albert W.; Sauer, John Michael; Konradi, Andrei W.; Ness, Daniel; Shopp, George; Pleiss, Michael A.; Freedman, Stephen B.; Schenk, Dale 分享 收藏
Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer Disease Basi, Guriqbal S.; Feinberg, Hadar; Oshidari, Farshid; Anderson, John; Barbour, Robin; Baker, Jeanne; Comery, Thomas A.; Diep, Linnea; Gill, Davinder; Johnson-Wood, Kelly; Goel, Amita; Grantcharova, Katerina; Lee, Mike; Li, Jingzhi; Partridge, Anthony; Griswold-Prenner, Irene; Piot, Nicolas; Walker, Don; Widom, Angela; Pangalos, Menelas N.; Seubert, Peter; Jacobsen, J. Steven; Schenk, Dale; Weis, William I. 分享 收藏
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