未登录 分享 收藏
分享 收藏
ASKCOS: Open-Source, Data-Driven Synthesis Planning ASKCOS：开源、数据驱动的合成规划 Tu, Zhengkai; Choure, Sourabh J.; Fong, Mun Hong; Roh, Jihye; Levin, Itai; Yu, Kevin; Joung, Joonyoung F.; Morgan, Nathan; Li, Shih-Cheng; Sun, Xiaoqi; Lin, Huiqian; Murnin, Mark; Liles, Jordan P.; Struble, Thomas J.; Fortunato, Michael E.; Liu, Mengjie; Green, William H.; Jensen, Klavs F.; Coley, Connor W. 分享 收藏
Exploring Cuneanes as Potential Benzene Isosteres and Energetic Materials: Scope and Mechanistic Investigations into Regioselective Rearrangements from Cubanes Son, Jeong-Yu; Aikonen, Santeri; Morgan, Nathan; Harmata, Alexander S.; Sabatini, Jesse J.; Sausa, Rosario C.; Byrd, Edward F. C.; Ess, Daniel H.; Paton, Robert S.; Stephenson, Corey R. J. 分享 收藏
分享 收藏
Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3′-hydroxyazetidin-1-yl)ethanone [BMS-8163361, an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Ye, Xiang-Yang; Chen, Stephanie Y.; Wu, Shung; Yoon, David S.; Wang, Haixia; Hong, Zhenqiu; O'Connor, Stephen P.; Li, Jun; Li, James J.; Kennedy, Lawrence J.; Walker, Steven J.; Nayeem, Akbar; Sheriff, Steven; Camac, Daniel M.; Ramamurthy, Vidyhashankar; Morin, Paul E.; Zebo, Rachel; Taylor, Joseph R.; Morgan, Nathan N.; Ponticiello, Randolph P.; Harrity, Thomas; Apedo, Atsu; Golla, Rajasree; Seethala, Ramakrishna; Wang, Mengmeng; Harper, Timothy W.; Sleczka, Bogdan G.; He, Bin; Kirby, Mark; Leahy, David K.; Li, Jianqing; Hanson, Ronald L.; Guo, Zhiwei; Li, Yi-Xin; DiMarco, John D.; Scaringe, Raymond; Maxwell, Brad; Moulin, Frederick; Barrish, Joel C.; Gordon, David A.; Robl, Jeffrey A. 分享 收藏
分享 收藏
Optimization of Activity, Selectivity, and Liability Profiles in 5-0xopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichloropheny1)-2-methyl5-oxo-5H-pyrrolo(3,4-b)pyridin-6(7H)-y1)-N,N-dimethylacetamide (BMS-767778) Devasthale, Pratik; Wang, Ying; Wang, Wei; Fevig, John; Feng, JianXin; Wang, Aiying; Harrity, Tom; Egan, Don; Morgan, Nathan; Cap, Michael; Fura, Aberra; Klei, Herbert E.; Kish, Kevin; Weigelt, Carolyn; Sun, Lucy; Levesque, Paul; Moulin, Frederic; Li, Yi-Xin; Zahler, Robert; Kirby, Mark S.; Hamann, Lawrence G. 分享 收藏
Discovery of dapagliflozin: A potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes Meng, Wei; Ellsworth, Bruce A.; Nirschl, Alexandra A.; McCann, Peggy J.; Patel, Manorama; Girotra, Ravindar N.; Wu, Gang; Sher, Philip M.; Morrison, Eamonn P.; Biller, Scott A.; Zahler, Robert; Deshpande, Prashant P.; Pullockaran, Annie; Hagan, Deborah L.; Morgan, Nathan; Taylor, Joseph R.; Obermeier, Mary T.; Humphreys, William G.; Khanna, Ashish; Discenza, Lorell; Robertson, James G.; Wang, Aiying; Hang, Songping; Wetterau, John R.; Janovitz, Evan B.; Flint, Oliver P.; Whaley, Jean M.; Washburn, William N. 分享 收藏
分享 收藏
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
