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Ki67 proliferation index in medullary thyroid carcinoma: a comparative study of multiple counting methods and validation of image analysis and deep learning platforms Nadeem, Saad; Hanna, Matthew G.; Viswanathan, Kartik; Marino, Joseph; Ahadi, Mahsa; Alzumaili, Bayan; Bani, Mohamed-Amine; Chiarucci, Federico; Chou, Angela; De Leo, Antonio; Fuchs, Talia L.; Lubin, Daniel J.; Luxford, Catherine; Magliocca, Kelly; Martinez, German; Shi, Qiuying; Sidhu, Stan; Al Ghuzlan, Abir; Gill, Anthony J.; Tallini, Giovanni; Ghossein, Ronald; Xu, Bin 分享 收藏
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening Woolford, Alison J. -A.; Pero, Joseph E.; Aravapalli, Sridhar; Berdini, Valerio; Coyle, Joseph E.; Day, Philip J.; Dodson, Andrew M.; Grondin, Pascal; Holding, Finn P.; Lee, Lydia Y. W.; Li, Peng; Manas, Eric S.; Marino, Joseph, Jr.; Martin, Agnes C. L.; McCleland, Brent W.; McMenamin, Rachel L.; Murray, Christopher W.; Neipp, Christopher E.; Page, Lee W.; Patel, Vipulkumar K.; Potvain, Florent; Rich, Sharna; Rivero, Ralph A.; Smith, Kirsten; Somers, Donald O.; Trottet, Lionel; Velagaleti, Ranganadh; Williams, Glyn; Xie, Ren 分享 收藏
Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy Seo, Kinya; Rainer, Peter P.; Hahn, Virginia Shalkey; Lee, Dong-ik; Jo, Su-Hyun; Andersen, Asger; Liu, Ting; Xu, Xiaoping; Willette, Robert N.; Lepore, John J.; Marino, Joseph P., Jr.; Birnbaumer, Lutz; Schnackenberg, Christine G.; Kass, David A. 分享 收藏
Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction Kompa, Andrew R.; Wang, Bing H.; Xu, Guoying; Zhang, Yuan; Ho, Pei-Yu; Eisennagel, Stephen; Thalji, Reema K.; Marino, Joseph P., Jr.; Kelly, Darren J.; Behm, David J.; Krum, Henry 分享 收藏
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Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore Marino, Joseph P., Jr.; Fisher, Paul W.; Hofmann, Glenn A.; Kirkpatrick, Robert B.; Janson, Cheryl A.; Johnson, Randall K.; Ma, Chun; Mattern, Michael; Meek, Thomas D.; Ryan, M. Dominic; Schulz, Christina; Smith, Ward W.; Tew, David G.; Tomazek, Thaddeus A., Jr.; Veber, Daniel F.; Xiong, Wenfang C.; Yamamoto, Yuuichi; Yamashita, Keizo; Yang, Guang; Thompson, Scott K. 分享 收藏
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities Doe, Chris; Bentley, Ross; Behm, David J.; Lafferty, Robert; Stavenger, Robert; Jung, David; Bamford, Mark; Panchal, Terry; Grygielko, Eugene; Wright, Lois L.; Smith, Gary K.; Chen, Zunxuan; Webb, Christine; Khandekar, Sanjay; Yi, Tracey; Kirkpatrick, Robert; Dul, Edward; Jolivette, Larry; Marino, Joseph P.; Willette, Robert; Lee, Dennis; Hu, Erding 分享 收藏
Discovery of aminofurazan-azabenzimidazoles as inhibitors of Rho-kinase with high kinase selectivity and antihypertensive activity Stavenger, Robert A.; Cui, Haifeng; Dowdell, Sarah E.; Franz, Robert G.; Gaitanopoulos, Dimitri E.; Goodman, Krista B.; Hilfiker, Mark A.; Ivy, Robert L.; Leber, Jack D.; Marino, Joseph P., Jr.; Oh, Hye-Ja; Viet, Andrew Q.; Xu, Weiwei; Ye, Guosen; Zhang, Daohua; Zhao, Yongdong; Jolivette, Larry J.; Head, Martha S.; Semus, Simon F.; Elkins, Patricia A.; Kirkpatrick, Robert B.; Dul, Edward; Khandekar, Sanjay S.; Yi, Tracey; Jung, David K.; Wright, Lois L.; Smith, Gary K.; Behm, David J.; Doe, Christopher P.; Bentley, Ross; Chen, Zunxuan X.; Hu, Erding; Lee, Dennis 分享 收藏
Synthetic LXR agonists increase LDL in CETP species Groot, PHE; Pearce, NJ; Yates, JW; Stocker, C; Sauermelch, C; Doe, CP; Willette, RN; Olzinski, A; Peters, T; d'Epagnier, D; Morasco, KO; Krawiec, JA; Webb, CL; Aravindhan, K; Jucker, B; Burgert, M; Ma, C; Marino, JP; Collins, JL; Macphee, CH; Thompson, SK; Jaye, M 分享 收藏
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, CY; Lu, Q; Kerrigan, JJ; Alvaro, MDL; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL 分享 收藏
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