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A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target He, Chen; Nora, George P.; Schneider, Eric L.; Kerr, Iain D.; Hansell, Elizabeth; Hirata, Ken; Gonzalez, David; Sajid, Mohammed; Boyd, Sarah E.; Hruz, Petr; Cobo, Eduardo R.; Le, Christine; Liu, Wei-ting; Eckmann, Lars; Dorrestein, Pieter C.; Houpt, Eric R.; Brinen, Linda S.; Craik, Charles S.; Roush, William R.; McKerrow, James; Reed, Sharon L. 分享 收藏
Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy Brak, Katrien; Kerr, Iain D.; Barrett, Kimberly T.; Fuchi, Nobuhiro; Debnath, Moumita; Ang, Kenny; Engel, Juan C.; McKerrow, James H.; Doyle, Patricia S.; Brinen, Linda S.; Ellman, Jonathan A. 分享 收藏
Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design Kerr, Iain D.; Lee, Ji H.; Farady, Christopher J.; Marion, Rachael; Rickert, Mathias; Sajid, Mohammed; Pandey, Kailash C.; Caffrey, Conor R.; Legac, Jennifer; Hansell, Elizabeth; McKerrow, James H.; Craik, Charles S.; Rosenthal, Philip J.; Brinen, Linda S. 分享 收藏
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Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica Stack, Colin M.; Caffrey, Conor R.; Donnelly, Sheila M.; Seshaadri, Amritha; Lowther, Jonathan; Tort, Jose F.; Collins, Peter R.; Robinson, Mark W.; Xu, Weibo; McKerrow, James H.; Craik, Charles S.; Geiger, Sebastian R.; Marion, Rachel; Brinen, Linda S.; Dalton, John P. 分享 收藏
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Development of α-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease Choe, Y; Brinen, LS; Price, MS; Engel, JC; Lange, M; Grisostomi, C; Weston, SG; Pallai, PV; Cheng, H; Hardy, LW; Hartsough, DS; McMakin, M; Tilton, RF; Baldino, CM; Craik, CS 分享 收藏
Crystal structure of a tandem cystathionine-β-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 Å resolution Miller, MD; Schwarzenbacher, R; von Delft, F; Abdubek, P; Ambing, E; Biorac, T; Brinen, LS; Canaves, JM; Cambell, J; Chiu, HJ; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Jardszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; Levin, I; McMullan, D; McPhillips, TM; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Robb, A; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 Å resolution Xu, QP; Schwarzenbacher, R; Page, R; Sims, E; Abdubek, P; Ambing, E; Biorac, T; Brinen, LS; Cambell, J; Canaves, JM; Chiu, HJ; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; Levin, I; McMullan, D; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Quijano, K; Reyes, R; Rezezadeh, F; Robb, A; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; von Delft, F; Wang, XH; West, B; Wolf, G; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 Å Resolution McMullan, D; Schwarzenbacher, R; Jaroszewski, L; von Delft, F; Klock, HE; Vincent, J; Quijano, K; Abdubek, P; Ambing, E; Biorac, T; Brinen, LS; Canaves, JM; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Eshaghi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Karlak, C; Koesema, E; Kreusch, A; Kuhn, P; Levin, I; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Jie, OY; Page, R; Reyes, R; Rezezadeh, F; Robb, A; Sims, E; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Lesley, SA; Wilson, IA 分享 收藏
Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 Å resolution 来自Thermotoga maritima的新型含锰铜 (TM1459) 的晶体结构，分辨率为1.65 Å Jaroszewski, L; Schwarzenbacher, R; von Delft, F; McMullan, D; Brinen, LS; Canaves, JM; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Levin, I; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Reyes, R; Rezezadeh, F; Robb, A; Sims, E; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-Å resolution reveals a new fold Bakolitsa, C; Schwarzenbacher, R; McMullan, D; Brinen, LS; Canaves, JM; Dai, XP; Deacon, AM; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Robb, A; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; von Delft, F; Wang, XH; West, B; Wolf, G; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution Heine, A; Canaves, JM; von Delft, F; Brinen, LS; Dai, XP; Deacon, AM; Elsliger, MA; Eshaghi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Guda, C; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; McMullan, D; McPhillips, TM; Miller, MA; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Robb, A; Rodrigues, K; Schwarzenbacher, R; Selby, TL; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; Wang, XH; West, B; Wolf, G; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution Levin, I; Schwarzenbacher, R; Page, R; Abdubek, P; Ambing, E; Biorac, T; Brinen, LS; Campbell, J; Canaves, JM; Chiu, HJ; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; McMullan, D; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Uyang, J; Quijano, K; Reyes, R; Rezezadeh, F; Robb, A; Sims, E; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; von Delft, F; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution Spraggon, G; Schwarzenbacher, R; Kreusch, A; McMullan, D; Brinen, LS; Canaves, JM; Dai, XP; Deacon, AM; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kuhn, P; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Rezezadeh, F; Robb, A; Sims, E; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; von Delft, F; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Lesley, SA; Wilson, IA 分享 收藏
Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution 来自Thermotoga maritima的推定的草酸脱羧酶 (TM1287) 的晶体结构1.95分辨率 Schwarzenbacher, R; von Delft, F; Jaroszewski, L; Abdubek, P; Ambing, E; Biorac, T; Brinen, L; Canaves, JM; Cambell, J; Chiu, HJ; Dai, XP; Deacon, AM; DiDonato, M; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Hampton, E; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; Levin, I; McMullan, D; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Robb, A; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 Å resolution Santelli, E; Schwarzenbacher, R; McMullan, D; Biorac, T; Brinen, LS; Canaves, JM; Campbell, J; Dai, XP; Deacon, AM; Elsliger, MA; Eshagi, S; Floyd, R; Godzik, A; Grittini, C; Grzechnik, SK; Jaroszewski, L; Karlak, C; Klock, HE; Koesema, E; Kovarik, JS; Kreusch, A; Kuhn, P; Lesley, SA; McPhillips, TM; Miller, MD; Morse, A; Moy, K; Ouyang, J; Page, R; Quijano, K; Rezezadeh, F; Robb, A; Sims, E; Spraggon, G; Stevens, RC; van den Bedem, H; Velasquez, J; Vincent, J; von Delft, F; Wang, XH; West, B; Wolf, G; Xu, QP; Hodgson, KO; Wooley, J; Wilson, IA 分享 收藏
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