Anne K. Soutar - Publications, H-index & Citations

Anne K. Soutar

Imperial College London

52H指数

214论文数

9.2K被引数

收录论文 39

发表时间

Improved cardiovascular outcomes following temporal advances in lipid-lowering therapy in a genetically-characterised cohort of familial hypercholesterolaemia homozygotes

ATHEROSCLEROSIS

IF5.7

2015-11-01

OAAI

Thompson, Gilbert R.; Seed, Mary; Naoumova, Rossi P.; Neuwirth, Clare; Walji, Shahenaz; Aitman, Timothy J.; Scott, James; Myant, Nicolas B.; Soutar, Anne K.

In Memoriam: Nick Myant (1917-2015)

JOURNAL OF LIPID RESEARCH

IF4.1

2015-06-01

OAAI

Gibbons, Geoffrey; Soutar, Anne; Thompson, Gilbert

The use of next-generation sequencing in clinical diagnosis of familial hypercholesterolemia

GENETICS IN MEDICINE

IF6.2

2013-12-01

OAAI

Vandrovcova, Jana; Thomas, Ellen R. A.; Atanur, Santosh S.; Norsworthy, Penny J.; Neuwirth, Clare; Tan, Yvonne; Kasperaviciute, Dalia; Biggs, Jennifer; Game, Laurence; Mueller, Michael; Soutar, Anne K.; Aitman, Timothy J.

Novel functional APOB mutations outside LDL-binding region causing familial hypercholesterolaemia

HUMAN MOLECULAR GENETICS

IF3.2

2013-11-13

OAAI

Alves, Ana Catarina; Etxebarria, Aitor; Soutar, Anne Katherine; Martin, Cesar; Bourbon, Mafalda

In vitro functional characterization of missense mutations in the LDLR gene

ATHEROSCLEROSIS

IF5.7

2012-11-01

PREAI

Silva, S.; Alves, A. C.; Patel, D.; Malho, R.; Soutar, A. K.; Bourbon, M.

Premature Senescence in Cells From Patients With Autosomal Recessive Hypercholesterolemia (ARH) Evidence for a Role for ARH in Mitosis

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2011-10-01

OAAI

Sun, Xi-Ming; Patel, Dilip D.; Acosta, Juan-Carlos; Gil, Jesus; Soutar, Anne K.

Increased Secretion of Lipoproteins in Transgenic Mice Expressing Human D374Y PCSK9 Under Physiological Genetic Control

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2010-07-01

OAAI

Herbert, Bronwen; Patel, Dilipkumar; Waddington, Simon N.; Eden, Emily R.; McAleenan, Alexandra; Sun, Xi-Ming; Soutar, Anne K.

Genetic diagnosis of familial hypercholesterolaemia: the importance of functional analysis of potential splice-site mutations

JOURNAL OF MEDICAL GENETICS

IF3.7

2009-05-01

OAAI

Bourbon, M.; Duarte, M. A.; Alves, A. C.; Medeiros, A. M.; Marques, L.; Soutar, A. K.

Degradation of LDLR protein mediated by 'gain of function' PCSK9 mutants in normal and ARH cells

ATHEROSCLEROSIS

IF5.7

2009-03-01

PREAI

Fasano, Tommaso; Sun, Xi-Ming; Patel, Dilipkumar D.; Soutar, Anne K.

Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: A randomized trial in healthy men 依泽替米贝和/或辛伐他汀对LDL受体蛋白表达以及LDL受体和hmg-coa还原酶基因表达的影响: 健康男性的随机试验

ATHEROSCLEROSIS

IF5.7

2008-05-01

PREAI

Gouni-Berthold, Ioanna; Berthold, Heiner K.; Gylling, Helena; Hallikainen, Maarit; Giannakidou, Eleni; Stier, Sebastian; Ko, Yon; Patel, Dilip; Soutar, Anne K.; Seedorf, Udo; Mantzoros, Christos S.; Plat, Jogchum; Krone, Wilhelm

Familial hypercholesterolaemia in Portugal 葡萄牙中的家族性高胆固醇血症

ATHEROSCLEROSIS

IF5.7

2008-02-01

OAAI

Bourbon, M.; Alves, A. C.; Medeiros, A. M.; Silva, S.; Soutar, A. K.

Genetic defects causing familial hypercholesterolaernia: Identification of deletions and duplications in the LDL-receptor gene and summary of all mutations found in patients attending the Hammersmith Hospital lipid clinic

ATHEROSCLEROSIS

IF5.7

2007-09-01

PREAI

Tosi, Isabella; Toledo-Leiva, Paola; Neuwirth, Clare; Naoumova, Rossi P.; Soutar, Anne K.

Adaptor protein Disabled-2 modulates low density lipoprotein receptor synthesis in fibroblasts from patients with autosomal recessive hypercholesterolaemia

HUMAN MOLECULAR GENETICS

IF3.2

2007-06-27

OAAI

Eden, Emily R.; Sun, Xi-Ming; Patel, Dilipkumar D.; Soutar, Anne K.

Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk

JOURNAL OF MEDICAL GENETICS

IF3.7

2006-07-06

238

OAAI

Humphries, S. E.; Whittall, R. A.; Hubbart, C. S.; Maplebeck, S.; Cooper, J. A.; Soutar, A. K.; Naoumova, R.; Thompson, G. R.; Seed, M.; Durrington, P. N.; Miller, J. P.; Betteridge, D. J. B.; Neil, H. A. W.

A single point mutation in the low-density lipoprotein receptor switches the degradation of its mature protein from the proteasome to the lysosome

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2006-01-01

PREAI

Martin de Llano, Jose Javier; Fuertes, Graciela; Andreu, Enrique Jose; Puig, Oscar; Chaves, F. Javier; Soutar, Anne K.; Armengod, Maria-Eugenia; Knecht, Erwin

Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene - Long-term follow-up and treatment response

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2005-12-01

208

OAAI

Naoumova, RP; Tosi, I; Patel, D; Neuwirth, C; Horswell, SD; Marais, AD; van Heyningen, C; Soutar, AK

Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia

HUMAN MOLECULAR GENETICS

IF3.2

2005-03-16

169