Yunn Chyn Tung

New York State Institute for Basic Research in Developmental Disabilities

H指数:16

被引数:1,221

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Therapeutic nanoliposome vaccine targeting multiple Aβ and tau epitopes reduces AD-like brain pathologies and rescues cognitive deficits in 3xTg-AD mice

靶向多个Aβ和tau表位的治疗性纳米脂质体疫苗可减少3xTg-AD小鼠的AD样脑病理并改善认知缺陷

brain, behavior, & immunity - health

IF0

2025-12-300

OAAI

Mechanism of Tau Hyperphosphorylation Involving Lysosomal Enzyme Asparagine Endopeptidase in a Mouse Model of Brain Ischemia

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-02-0640

PREAI

A pentavalent peptide vaccine elicits Aβ and tau antibodies with prophylactic activity in an Alzheimer's disease mouse model

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2024-11-010

PRE

Two simple assays for assessing the seeding activity of proteopathic tau

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2023-04-061

OAAI

Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation

靶向微管结合结构域的Tau抗体77G7抑制蛋白性tau至种子tau聚集

CNS NEUROSCIENCE & THERAPEUTICS

IF5

2022-09-176

OAAI

Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2022-09-055

Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2021-07-2114

OAAI

Dephosphorylation Passivates the Seeding Activity of Oligomeric Tau Derived From Alzheimer's Brain

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2021-05-1310

OAAI

Alzheimer's disease brain contains tau fractions with differential prion-like activities

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2021-02-1736

OAAI

Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain

阿尔茨海默病大脑灰质与白质中具有播种能力的Tau

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2021-01-083

PREAI

Pathological Tau From Alzheimer's Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

来自阿尔茨海默氏症大脑的病理性Tau在体内诱导位点特异性过度磷酸化以及抗SDS和还原剂的Tau聚集

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2019-03-0591

OAAI

Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2018-07-0322

OAAI

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 x Tg-AD mice

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2018-01-3168

OAAI

Tau passive immunization inhibits not only tau but also Aβ pathology

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2017-01-10107

OAAI

Hyperphosphorylation determines both the spread and the morphology of tau pathology

ALZHEIMERS & DEMENTIA

IF11.1

2016-04-28117

PREAI

Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2015-03-1827

PREAI

Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease

NEUROBIOLOGY OF AGING

IF3.5

2014-12-0150

OAAI

Animal Models of the Sporadic Form of Alzheimer's Disease: Focus on the Disease and Not Just the Lesions

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2013-09-2421

PREAI

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-06-01111

OAAI

An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide

ACTA NEUROPATHOLOGICA

IF9.3

2011-11-1579

Yunn Chyn Tung

个人简介

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