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EVALUATION OF AB-101, AN ALLOGENEIC CORD BLOOD-DERIVED NATURAL KILLER (NK) CELL THERAPY, AS AN ADCC ENHANCER IN HEMATOLOGIC AND SOLID TUMORS Rogers, Paul; Yang, Bitna; Kim, Hyojin; Kim, Yusun; Cho, Sunglim; Morin, Bret; Conerty, Amanda; Karyampudi, Lavakumar; Guerrettaz, Lisa; Flynn, Peter; Min, Bokyung; Raymon, Heather 分享 收藏
Phase 1 study of anti-CD47 monoclonal antibody CC-90002 in patients with relapsed/refractory acute myeloid leukemia and high-risk myelodysplastic syndromes Zeidan, Amer M.; DeAngelo, Daniel J.; Palmer, Jeanne; Seet, Christopher S.; Tallman, Martin S.; Wei, Xin; Raymon, Heather; Sriraman, Priya; Kopytek, Stephan; Bewersdorf, Jan Philipp; Burgess, Michael R.; Hege, Kristen; Stock, Wendy 分享 收藏
DEVELOPMENT OF AB-201, A NOVEL ALLOGENEIC ANTI-HER2-SPECIFIC CAR-NK CELL THERAPY FOR THE TREATMENT OF HER2+TUMORS Lim, Hoyong; Medcalf, Amanda; Guerrettaz, Lisa; Choi, Eun Ji; Kim, Hansol; Yang, Bitna; Kim, Eun Ji; Lee, Eun-Sol; Kim, Jeong Min; Kim, Yusun; Min, Bokyung; Paik, Sang-Min; Nam, Hyeong Jin; Han, Seungryel; Somanchi, Srinivas; Helsel, Eugene; Litten, Jason; Flynn, Peter; Raymon, Heather; Hwang, Yu-Kyeong 分享 收藏
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies Dylgjeri, Emanuela; McNair, Christopher; Goodwin, Jonathan F.; Raymon, Heather K.; Mccue, Peter A.; Shafi, Ayesha A.; Leiby, Benjamin E.; de Leeuw, Renee; Kothari, Vishal; McCann, Jennifer J.; Mandigo, Amy C.; Chand, Saswati N.; Schiewer, Matthew J.; Brand, Lucas J.; Vasilevskaya, Irina; Gordon, Nicolas; Laufer, Talya S.; Gomella, Leonard G.; Lallas, Costas D.; Trabulsi, Edouard J.; Feng, Felix Y.; Filvaroff, Ellen H.; Hege, Kristin; Rathkopf, Dana; Knudsen, Karen E. 分享 收藏
Synthetic Lethal Strategy Identifies a Potent and Selective TTK and CLK1/2 Inhibitor for Treatment of Triple-Negative Breast Cancer with a Compromised G1-S Checkpoint Zhu, Dan; Xu, Shuichan; Deyanat-Yazdi, Gordafaried; Peng, Sophie X.; Barnes, Leo A.; Narla, Rama Krishna; Tran, Tam; Mikolon, David; Ning, Yuhong; Shi, Tao; Jiang, Ning; Raymon, Heather K.; Riggs, Jennifer R.; Boylan, John F. 分享 收藏
CC-90002 (anti-CD47 antibody) in vivo anti-tumor activity is associated with an increase in M1-polarized macrophages Zheng, Bing; Wong, Piu; Yang, WenQing; Narla, Rama; Burgess, Michael; Escoubet, Laure; Raymon, Heather; Hariharan, Kandasamy; Boylan, John; Hege, Kristen; Sung, Victoria 分享 收藏
The humanized anti-CD47 monclonal antibody, CC-90002, has antitumor activity in vitro and in vivo Narla, Rama Krishna; Modi, Hardik; Wong, Lilly; Abassian, Mahan; Bauer, Daniel; Desai, Pragnya; Gaffney, Bonny; Jackson, Pilgrim; Leisten, Jim; Liu, Jing; Lopez-Girona, Antonia; Romero, Maria; Yang, WenQing; Eckelman, Brendan P.; Deveraux, Quinn; Phillips, Laurie; Raymon, Heather K.; Escoubet, Laure; Boylan, John; Hariharan, Kandasamy 分享 收藏
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Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115 Mortensen, Deborah S.; Perrin-Ninkovic, Sophie M.; Shevlin, Graziella; Elsner, Jan; Zhao, Jingjing; Whitefield, Brandon; Tehrani, Lida; Sapienza, John; Riggs, Jennifer R.; Parnes, Jason S.; Papa, Patrick; Packard, Garrick; Lee, Branden G. S.; Harris, Roy; Correa, Matthew; Bahmanyar, Sogole; Richardson, Samantha J.; Peng, Sophie X.; Leisten, Jim; Khambatta, Godrej; Hickman, Matt; Gamez, James C.; Bisonette, Rene R.; Apuy, Julius; Gathers, Brian E.; Canan, Stacie S.; Moghaddam, Mehran F.; Raymon, Heather K.; Worland, Peter; Narla, Rama Krishna; Fultz, Kimberly E.; Sankar, Sabita 分享 收藏
Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223 Mortensen, Deborah S.; Perrin-Ninkovic, Sophie M.; Shevlin, Graziella; Zhao, Jingjing; Packard, Garrick; Bahmanyar, Sogole; Correa, Matthew; Elsner, Jan; Harris, Roy; Lee, Branden G. S.; Papa, Patrick; Parnes, Jason S.; Riggs, Jennifer R.; Sapienza, John; Tehrani, Lida; Whitefield, Brandon; Apuy, Julius; Bisonette, Rene R.; Gamez, James C.; Hickman, Matt; Khambatta, Godrej; Leisten, Jim; Peng, Sophie X.; Richardson, Samantha J.; Gathers, Brian E.; Callan, Stacie S.; Moghaddam, Mehran F.; Raymon, Heather K.; Worland, Peter; Narla, Rama Krishna; Fultz, Kimberly E.; Sankar, Sabita 分享 收藏
CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization Mortensen, Deborah S.; Fultz, Kimberly E.; Xu, Shuichan; Xu, Weiming; Packard, Garrick; Khambatta, Godrej; Gamez, James C.; Leisten, Jim; Zhao, Jingjing; Apuy, Julius; Ghoreishi, Kamran; Hickman, Matt; Narla, Rama Krishna; Bissonette, Rene; Richardson, Samantha; Peng, Sophie X.; Perrin-Ninkovic, Sophie; Tran, Tam; Shi, Tao; Yang, Wen Qing; Tong, Zeen; Cathers, Brian E.; Moghaddam, Mehran F.; Canan, Stacie S.; Worland, Peter; Sankar, Sabita; Raymon, Heather K. 分享 收藏
Antitumor activity of mTOR kinase and DNA-PK inhibitor CC-115 in a mouse model of glioblastoma Raymon, H.; Peng, S.; Katz, J.; Zhao, C.; Phan, C.; Moghaddam, M. F.; Fultz, K. E.; Sankar, S.; Mortensen, D. S.; Narla, R. K. 分享 收藏
Preclinical characterization of CC-115, a novel inhibitor of DNA-PK and mTOR kinase currently under clinical investigation Mortensen, D. S.; Fultz, K. E.; Xu, W.; Tsuji, T.; Hickman, M.; Abbasian, M.; Khambatta, G.; Cathers, B.; Worland, P.; Moghaddam, M. F.; Apuy, J.; Richardson, S.; Elsner, J.; Shevlin, G.; Perrin-Ninkovic, S.; Canan, S.; Raymon, H. K.; Narla, R. K.; Peng, S.; Sankar, S. 分享 收藏
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Antitumor activity of mTOR kinase inhibitor CC-223 in a mouse model of prostate cancer. Narla, Rama Krishna; Pang, Sophie; Gamez, Jim; Katz, Jason; Apuy, Julius; Moghaddam, Mehran; Fultz, Kimberly E.; Sankar, Sabita; Mortensen, Deborah S.; Raymon, Heather K. 分享 收藏
The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas Gini, Beatrice; Zanca, Ciro; Guo, Deliang; Matsutani, Tomoo; Masui, Kenta; Ikegami, Shiro; Yang, Huijun; Nathanson, David; Villa, Genaro R.; Shackelford, David; Zhu, Shaojun; Tanaka, Kazuhiro; Babic, Ivan; Akhavan, David; Lin, Kelly; Assuncao, Alvaro; Gu, Yuchao; Bonetti, Bruno; Mortensen, Deborah S.; Xu, Shuichan; Raymon, Heather K.; Cavenee, Webster K.; Furnari, Frank B.; James, C. David; Kroemer, Guido; Heath, James R.; Hege, Kristen; Chopra, Rajesh; Cloughesy, Timothy F.; Mischel, Paul S. 分享 收藏
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The Discovery and Preclinical Characterization of CC-223, a Novel mTOR Kinase Inhibitor Under Clinical Investigation Mortensen, D. S.; Fultz, K. E.; Hickman, M.; Khambatta, G.; Xu, W.; Perrin-Ninkovic, S. M.; Zhao, J.; Narla, R. K.; Raymon, H.; Sankar, S. 分享 收藏
The mTOR kinase inhibitor, CC214, preferentially blocks the growth of EGFRvIII-activated glioblastomas Gini, Beatrice; Guo, Deliang; Nathanson, David; Shackelford, David; Zhu, Shaojun; Yang, Huijun; Tanaka, Kazuhiro; Babic, Ivan; Akhavan, David; Bonetti, Bruno; Mortensen, Deborah; Xu, Shuichan; Raymon, Heather; Chopra, Rajesh; Mischel, Paul 分享 收藏
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