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Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity 7A5: 具有不同激动剂特性的人CD137 (4-1BB) 受体结合单克隆抗体，可促进抗肿瘤免疫 Kotanides, Helen; Sattler, Rose Marie; Lebron, Maria B.; Carpenito, Carmine; Shen, Juqun; Li, Jingxing; Surguladze, David; Haidar, Jaafar N.; Burns, Colleen; Shen, Leyi; Inigo, Ivan; Pennello, Anthony L.; Forest, Amelie; Chen, Xinlei; Chin, Darin; Sonyi, Andreas; Topper, Michael; Boucher, Lauren; Sharma, Prachi; Zhang, Yiwei; Burtrum, Douglas; Novosiadly, Ruslan D.; Ludwig, Dale L.; Plowman, Gregory D.; Kalos, Michael 分享 收藏
LY3076226, a novel anti-FGFR3 antibody drug conjugate exhibits potent and durable anti-tumor activity in tumor models harboring FGFR3 mutations or fusions Surguladze, David; Pennello, Anthony; Ren, Xiaodi; Mack, Tim; Rigby, Alan; Balderes, Paul; Navarro, Elizabeth; Amaladas, Nelusha; Eastman, Scott; Topper, Michael; Yao, Yung-Mae; Moxham, Chris; Plowman, Gregory; Ludwig, Dale 分享 收藏
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Preclinical characterization of the anti-PD-L1 monoclonal antibody LY3300054 Carpenito, Carmine; Li, Yiwen; Wang, George X.; Malabunga, Maria S.; Haidar, Jaafar N.; Forest, Amelie; Murphy, Mary Y.; Hall, Gerald E.; Wang, Cindy; Shen, Leyi; Sonyi, Andreas; Chin, Darin; Pennello, Anthony L.; Inigo, Ivan V.; Surguladze, David; Yao, Yung-mae; Burtrum, Douglas; Novosiadly, Ruslan D.; Persaud, Kris; Ludwig, Dale L.; Kalos, Michael D. 分享 收藏
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 (vol 6, 31, 2018) Li, Yiwen; Carpenito, Carmine; Wang, George; Surguladze, David; Forest, Amelie; Malabunga, Maria; Murphy, Mary; Zhang, Yiwei; Sonyi, Andreas; Chin, Darin; Burtrum, Douglas; Inigo, Ivan; Pennello, Anthony; Shen, Leyi; Malherbe, Laurent; Chen, Xinlei; Hall, Gerald; Haidar, Jaafar N.; Ludwig, Dale L.; Novosiadly, Ruslan D.; Kalos, Michael 分享 收藏
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 Li, Yiwen; Carpenito, Carmine; Wang, George; Surguladze, David; Forest, Amelie; Malabunga, Maria; Murphy, Mary; Zhang, Yiwei; Sonyi, Andreas; Chin, Darin; Burtrum, Douglas; Inigo, Ivan; Pennello, Anthony; Shen, Leyi; Malherbe, Laurent; Chen, Xinlei; Hall, Gerald; Haidar, Jaafar N.; Ludwig, Dale L.; Novosiadly, Ruslan D.; Kalos, Michael 分享 收藏
An Open-Label, Dose-Escalation Phase I Study of Anti-TYRP1 Monoclonal Antibody IMC-20D7S for Patients with Relapsed or Refractory Melanoma Khalil, Danny N.; Postow, Michael A.; Ibrahim, Nageatte; Ludwig, Dale L.; Cosaert, Jan; Kambhampati, Siva Rama Prasad; Tang, Shande; Grebennik, Dmitri; Kauh, John Sae Wook; Lenz, Heinz-Josef; Flaherty, Keith T.; Hodi, F. Stephen; Lawrence, Donald P.; Wolchok, Jedd D. 分享 收藏
Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody Yin, Yongjun; Ren, Xiaodi; Smith, Craig; Guo, Qianxu; Malabunga, Maria; Guernah, Ilhem; Zhang, Yiwei; Shen, Juqun; Sun, Haijun; Chehab, Nabil; Loizos, Nick; Ludwig, Dale L.; Ornitz, David M. 分享 收藏
Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin Receptor Forest, Amelie; Amatulli, Michael; Ludwig, Dale L.; Damoci, Christopher B.; Wang, Ying; Burns, Colleen A.; Donoho, Gregory P.; Zanella, Nina; Fiebig, Heinz H.; Prewett, Marie C.; Surguladze, David; DeLigio, James T.; Houghton, Peter J.; Smith, Malcolm A.; Novosiadly, Ruslan 分享 收藏
A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation 同时靶向igf-ir和VEGF降解的双功能抗体-受体结构域融合蛋白 Shen, Yang; Zeng, Lin; Novosyadlyy, Ruslan; Forest, Amelie; Zhu, Aiping; Korytko, Andrew; Zhang, Haifan; Eastman, Scott W.; Topper, Michael; Hindi, Sagit; Covino, Nicole; Persaud, Kris; Kang, Yun; Burtrum, Douglas; Surguladze, David; Prewett, Marie; Chintharlapalli, Sudhakar; Wroblewski, Victor J.; Shen, Juqun; Balderes, Paul; Zhu, Zhenping; Snavely, Marshall; Ludwig, Dale L. 分享 收藏
Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cell-mediated cytotoxicity Shen, Yang; Zeng, Lin; Zhu, Aiping; Blanc, Tim; Patel, Dipa; Pennello, Anthony; Bari, Amtul; Ng, Stanley; Persaud, Kris; Kang, Yun (Kenneth); Balderes, Paul; Surguladze, David; Hindi, Sagit; Zhou, Qinwei; Ludwig, Dale L.; Snavely, Marshall 分享 收藏
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Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models. Li, Yanxia; Mathew, Sneha; Wu, Lan; Wang, Ying; Persaud, Kris; Burtrum, Douglas; Balderes, Paul; Surguladze, David; Haurum, John; Ludwig, Dale; Doody, Jacqueline 分享 收藏
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