Wayne D. Bowen - Publications, H-index & Citations

Wayne D. Bowen

Brown University

44H指数

189论文数

6.5K被引数

收录论文 53

发表时间

Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2021-09-01

OAAI

Liu, Cheri Z.; Mottinelli, Marco; Nicholson, Hilary E.; McVeigh, Bridget M.; Wong, Neelum K.; McCurdy, Christopher R.; Bowen, Wayne D.

Pharmacological characterization of sigma-2 receptor ligand-induced metabolic stimulation in human SK-N-SH neuroblastoma cells

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

McVeigh, Bridget M.; Oakes, Alissa K.; Liu, Cheri Z.; Mesangeau, Christophe; Alsharif, Walid F.; McCurdy, Christopher R.; Bowen, Wayne D.

Differential sigma-2 receptor-mediated metabolic stimulative and apoptotic effects of monovalent CM571 and its homo-bivalent counterpart, MAM03055A

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Liu, Cheri Z.; McVeigh, Bridget M.; Mottinelli, Marco; Nicholson, Hilary E.; McCurdy, Christopher R.; Bowen, Wayne D.

Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivativess

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-02-01

OAAI

Nicholson, Hilary E.; Alsharif, Walid F.; Comeau, Anthony B.; Mesangeau, Christophe; Intagliata, Sebastiano; Mottinelli, Marco; McCurdy, Christopher R.; Bowen, Wayne D.

Identification and characterization of MAM03055A, a novel bivalent sigma-2 receptor agonist

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Liu, Cheri Z.; Mottinelli, Marco; Nicholson, Hilary E.; Zhong, Eric; McCurdy, Christopher R.; Bowen, Wayne D.

The role of ceramide in the dual cytotoxic and metabolic stimulative effects of sigma-2 receptors

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Liu, Cheri Z.; Sukharevsky, Ellen; Bowen, Wayne D.

Structural changes to SN79 result in ligands that stimulate a metabolic function of sigma-2 receptors

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Nicholson, Hilary Elaine; Alsharif, Walid; McCurdy, Christopher R.; Bowen, Wayne D.

Sigma-2 receptor-mediated cell death is altered by cell density in human SK-N-SH neuroblastoma 2-D and 3-D cultures

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Liu, Cheri Z.; Behnam, Vira; Bowen, Wayne D.

Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastomas

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2016-02-01

OAAI

Nicholson, Hilary; Mesangeau, Christophe; McCurdy, Christopher R.; Bowen, Wayne D.

Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor activation in 3D culture

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Chou, Timothy; Jacobs, Michaele; Nicholson, Hilary; Bowen, Wayne D.

Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2015-08-01

OAAI

Nicholson, Hilary; Comeau, Anthony; Mesangeau, Christophe; McCurdy, Christopher R.; Bowen, Wayne D.

C6Ceramide as potential novel therapy for pancreatic cancer

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Limaye, Apurva; Mathiowitz, Edith; Bowen, Wayne D.; Wanebo, Harold

Sigma-2 receptor-induced cell death: a novel approach to triple-negative breast cancer treatment

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Liu, Zongyi; Nicholson, Hilary E.; Bowen, Wayne D.

Evaluation of structural changes in SN79-derived sigma-2 receptor modulators: effect on apoptotic efficacy in SK-N-SH neuroblastoma

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Nicholson, Hilary Elaine; Alsharif, Walid; McCurdy, Christopher R.; Bowen, Wayne D.

Characterization of CM-572 and CM-769: Novel irreversible modulators of sigma-2 receptor function

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Nicholson, Hilary E.; Chia, Pei Ling; Comeau, Anthony; Mesangeau, Christophe; McCurdy, Christopher; Bowen, Wayne D.

Liposomal C6 Ceramide appears to potentiate chemotoxicity of paclitaxel, gemcitabine and cetuximab against aggressive pancreatic cancer.

MOLECULAR CANCER THERAPEUTICS

IF5.5

2013-11-01

PREAI

Wanebo, Harold J.; Cao, Cong; Lu, Shaun; Shrayer, David; Wan, Yinsheng; Bowen, Wayne; Bowen, Wayne

Trojan-Horse Nanotube On-Command Intracellular Drug Delivery 特洛伊木马纳米管命令细胞内药物输送

NANO LETTERS

IF9.1

2012-10-25

OAAI

Wu, Chia-Hsuan; Cao, Cong; Kim, Jin Ho; Hsu, Chih-Hsun; Wanebo, Harold J.; Bowen, Wayne D.; Xu, Jimmy; Marshall, John

Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [H-3]-noradrenaline release in rat hippocampal slices

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-07-19

OAAI

Monnet, FP; deCosta, BR; Bowen, WD

C6 ceramide sensitizes multiple aggressive pancreatic cancer cell lines to gemcitabine, paclitaxel and cetuximab mediated anti tumor effects in vivo and in vitro

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Wanebo, Harold J.; Lu, Shan; Cong, Cao; Shrayer, David; Wan, Yinsheng; Bowen, Wayne

C6-ceramide sensitizes the aggressive L3-6 pancreatic cancer cell line to paclitaxel-mediated antitumor effects in vivo and in vitro

CANCER RESEARCH

IF16.6

2010-04-01

PREAI

Cao, Cong; Bowen, Wayne; Wanebo, Harold; Wan, Yansheung; Ji, Fran; Lu, Su; Shrayer, David

研究方向