Timothy P. Riley - Publications, H-index & Citations

Timothy P. Riley

Amgen

15H指数

58论文数

846被引数

收录论文 16

发表时间

Onboard, tethered IL-12 boosts potency of the Tmod NOT gate and preserves selectivity 在载具上，系留的IL-12增强了Tmod非门的有效性并保持了选择性

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2025-05-21

OAAI

Zhang, Jingli A.; Imboden, Sara; Lee, Dongwoo; Zampieri, Alexandre; Shafaattalab, Sanam; Liang, Jushen; Bruno, Richele; Torres, Jon; Partin, Alexander; Daris, Mark E.; Riley, Timothy P.; Kamb, Alexander

Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy 多靶点、非门控CAR-T细胞作为保护正常系用于血液癌症治疗的策略

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-03-21

OAAI

DiAndreth, Breanna; Nesterenko, Pavlo A.; Winters, Aaron G.; Flynn, Aaron D.; Jette, Claudia A.; Suryawanshi, Vasantika; Shafaattalab, Sanam; Martire, Sara; Daris, Mark; Moore, Elizabeth; Elshimali, Ryan; Gill, Tanveer; Riley, Timothy P.; Miller, Sara; Netirojjanakul, Chawita; Hamburger, Agnes E.; Kamb, Alexander

Geometric parameters that affect the behavior of logic-gated CAR T cells 影响逻辑门控CAR T细胞行为的几何参数

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-01-26

OAAI

Partin, Alexander C.; Bruno, Richele; Shafaattalab, Sanam; Vander Mause, Erica; Winters, Aaron; Daris, Mark; Gahrs, Casey; Jette, Claudia A.; Diandreth, Breanna; Sandberg, Mark L.; Hamburger, Agnes E.; Kamb, Alexander; Riley, Timothy P.

Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features

MABS

IF7.3

2023-01-22

OAAI

Harmalkar, Ameya; Rao, Roshan; Xie, Yuxuan Richard; Honer, Jonas; Deisting, Wibke; Anlahr, Jonas; Hoenig, Anja; Czwikla, Julia; Sienz-Widmann, Eva; Rau, Doris; Rice, Austin J.; Riley, Timothy P.; Li, Danqing; Catterall, Hannah B.; Tinberg, Christine E.; Gray, Jeffrey J.; Wei, Kathy Y.

HLA-A*02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen

MOLECULAR THERAPY ONCOLYTICS

IF5.3

2022-12-01

OAAI

Mock, Jee-Young; Winters, Aaron; Riley, Timothy P.; Bruno, Richele; Naradikian, Martin S.; Sharma, Shruti; Jette, Claudia A.; Elshimali, Ryan; Gahrs, Casey; Toledo-Warshaviak, Dora; West Jr, Anthony P.; Kamb, Alexander; Hamburger, Agnes E.

Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design 通过结构引导设计提高SARS-CoV-2 Spike蛋白的融合前构象稳定性

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-04-22

OAAI

Riley, Timothy P.; Chou, Hui-Ting; Hu, Ruozhen; Bzymek, Krzysztof P.; Correia, Ana R.; Partin, Alexander C.; Li, Danqing; Gong, Danyang; Wang, Zhulun; Yu, Xinchao; Manzanillo, Paolo; Garces, Fernando

Rational selection of building blocks for the assembly of bispecific antibodies

MABS

IF7.3

2021-01-05

OAAI

Gong, Danyang; Riley, Timothy P.; Bzymek, Krzysztof P.; Correia, Ana R.; Li, Danqing; Spahr, Christopher; Robinson, John H.; Case, Ryan B.; Wang, Zhulun; Garces, Fernando

Structure Based Prediction of Neoantigen Immunogenicity

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-08-28

OAAI

Riley, Timothy P.; Keller, Grant L. J.; Smith, Angela R.; Davancaze, Lauren M.; Arbuiso, Alyssa G.; Devlin, Jason R.; Baker, Brian M.

Improving T Cell Receptor On-Target Specificity via Structure-Guided Design

MOLECULAR THERAPY

IF12

2019-02-01

OAAI

Hellman, Lance M.; Foley, Kendra C.; Singh, Nishant K.; Alonso, Jesus A.; Riley, Timothy P.; Devlin, Jason R.; Ayres, Cory M.; Keller, Grant L. J.; Zhang, Yuting; Vander Kooi, Craig W.; Nishimura, Michael I.; Baker, Brian M.

The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2018-12-01

OAAI

Riley, Timothy P.; Baker, Brian M.

T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability

NATURE CHEMICAL BIOLOGY

IF13.7

2018-09-17

OAAI

Riley, Timothy P.; Hellman, Lance M.; Gee, Marvin H.; Mendoza, Juan L.; Alonso, Jesus A.; Foley, Kendra C.; Nishimura, Michael I.; Vander Kooi, Craig W.; Garcia, K. Christopher; Baker, Brian M.

Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2018-08-13

OAAI

Eby, Jonathan M.; Smith, Angela R.; Riley, Timothy P.; Cosgrove, Cormac; Ankney, Christian M.; Henning, Steven W.; Paulos, Chrystal M.; Garrett-Mayer, Elizabeth; Luiten, Rosalie M.; Nishimura, Michael I.; Baker, Brian M.; Le Poole, I. Caroline

Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2017-07-25

OAAI

Ayres, Cory M.; Riley, Timothy P.; Corcelli, Steven A.; Baker, Brian M.

Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-11-01

OAAI

Harris, Daniel T.; Wang, Ningyan; Riley, Timothy P.; Anderson, Scott D.; Singh, Nishant K.; Procko, Erik; Baker, Brian M.; Kranz, David M.

Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2016-02-26

OAAI

Spear, Timothy T.; Riley, Timothy P.; Lyons, Gretchen E.; Callender, Glenda G.; Roszkowski, Jeffrey J.; Wang, Yuan; Simms, Patricia E.; Scurti, Gina M.; Foley, Kendra C.; Murray, David C.; Hellman, Lance M.; McMahan, Rachel H.; Iwashima, Makio; Garrett-Mayer, Elizabeth; Rosen, Hugo R.; Baker, Brian M.; Nishimura, Michael I.

How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-02-16

OAAI

Blevins, Sydney J.; Pierce, Brian G.; Singh, Nishant K.; Riley, Timothy P.; Wang, Yuan; Spear, Timothy T.; Nishimura, Michael I.; Weng, Zhiping; Baker, Brian M.

研究方向