Thomas J. Sayers - Publications, H-index & Citations

Thomas J. Sayers

Frederick National Laboratory for Cancer Research

49H指数

241论文数

7.3K被引数

收录论文 53

发表时间

CD8+ T–NK cell crosstalk establishes preemptive immunosurveillance to eliminate antigen–escape tumors CD8+ T细胞与NK细胞的相互作用建立了先发制人的免疫监视，以清除抗原逃逸肿瘤

Frontiers in Immunology

IF5.9

2025-09-22

OAAI

Roman V. Uzhachenko‡; Salvador González Ochoa‡; Thanigaivelan Kanagasabai‡; Harshana Rajakaruna; Menaka C. Thounaojam; Maria Teresa P. de Aquino†; Tanu Rana†; Lino Costa; Alexander Terekhov; William H. Hofmeister; Thomas J. Sayers; Claude Boyer; Alla V. Ivanova; J. Shawn Goodwin; Anne-Marie Schmitt-Verhulst; Anil Shanker

Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma

JOURNAL OF NATURAL PRODUCTS

IF3.6

2021-12-01

PREAI

Wijeratne, E. M. Kithsiri; Xu, Ya-Ming; Liu, Manping X.; Inacio, Marielle C.; Brooks, Alan D.; Tewary, Poonam; Sayers, Thomas J.; Gunatilaka, A. A. Leslie

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

CANCER RESEARCH

IF16.6

2021-04-09

OAAI

Tewary, Poonam; Brooks, Alan D.; Xu, Ya-Ming; Wijeratne, E. M. Kithsiri; Babyak, Ashley L.; Back, Timothy C.; Chari, Raj; Evans, Christine N.; Henrich, Curtis J.; Meyer, Thomas J.; Edmondson, Elijah F.; de Aquino, Maria T. Prudente; Kanagasabai, Thanigaivelan; Shanker, Anil; Gunatilaka, A. A. Leslie; Sayers, Thomas J.

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

SCIENTIFIC REPORTS

IF3.9

2018-11-30

OAAI

Nalli, Ancy D.; Brown, Lauren E.; Thomas, Cheryl L.; Sayers, Thomas J.; Porco, John A., Jr.; Henrich, Curtis J.

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica

PHYTOCHEMISTRY

IF3.4

2018-08-01

OAAI

Xu, Ya-Ming; Wijeratne, E. M. Kithsiri; Brooks, Alan D.; Tewary, Poonam; Xuan, Li-Jiang; Wang, Wen-Qiong; Sayers, Thomas J.; Gunatilaka, A. A. Leslie

17beta-hydroxywithanolides inhibit the proliferation of castration-resistant prostate cancer cells by reducing levels of cFLIP

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Brooks, Alan D.; Wright, Nicola E.; Xu, Ya-ming; Wijeratne, Kithsiri; Tewary, Poonam; Cross, Neil; Gunatilaka, A. A. Leslie; Sayers, Thomas J.

Rocaglamide A and synthetic analogues sensitize resistant renal carcinoma cells to TRAIL-induced apoptosis and inhibit cell proliferation

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Nalli, Ancy D.; Brown, Lauren E.; Thomas, Cheryl L.; Sayers, Thomas J.; Porco, John A.; Henrich, Curtis J.

A specific 17-beta-hydroxywithanolide (LG-02) sensitizes cancer cells to apoptosis in response to TRAIL and TLR3 ligands

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Tewary, Poonam; Brooks, Alan D.; Xu, Ya-ming; Wijeratne, Kithsiri E. M.; Gunatilaka, Leslie A.; Sayers, Thomas J.

Promoting caspase-8-dependent apoptosis signaling using 17-beta-hydroxywithanolides

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Brooks, Alan D.; Xu, Ya-ming; Wijeratne, E. M. Kithsiri; Henrich, Curtis J.; Tewary, Poonam; Gunatilaka, Leslie; Sayers, Thomas J.

Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells

JOURNAL OF NATURAL PRODUCTS

IF3.6

2017-06-15

OAAI

Xu, Ya-Ming; Wijeratne, E. M. Kithsiri; Babyak, Ashley L.; Marks, Hanna R.; Brooks, Alan D.; Tewary, Poonam; Xuan, Li-Jiang; Wang, Wen-Qiong; Sayers, Thomas J.; Gunatilaka, A. A. Leslie

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-03-21

OAAI

Xu, Ya-Ming; Brooks, Alan D.; Wijeratne, E. M. Kithsiri; Henrich, Curtis J.; Tewary, Poonam; Sayers, Thomas J.; Gunatilaka, A. A. Leslie

Promoting TRAIL apoptosis signaling using 17-beta-hydroxywithanolides

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Brooks, Alan D.; Xu, Ya-ming; Wijeratne, E. M. Kithsiri; Tewary, Poonam; Henrich, Curtis J.; Thomas, Cheryl L.; Gunatilaka, A. A. Leslie; Sayers, Thomas J.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

CANCER RESEARCH

IF16.6

2015-12-14

OAAI

Shanker, Anil; Pellom, Samuel T., Jr.; Dudimah, Duafalia F.; Thounaojam, Menaka C.; de Kluyver, Rachel L.; Brooks, Alan D.; Yagita, Hideo; McVicar, Daniel W.; Murphy, William J.; Longo, Dan L.; Sayers, Thomas J.

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

JOURNAL OF IMMUNOLOGY

IF3.4

2015-10-15

198

OAAI

Ames, Erik; Canter, Robert J.; Grossenbacher, Steven K.; Mac, Stephanie; Chen, Mingyi; Smith, Rachel C.; Hagino, Takeshi; Perez-Cunningham, Jessica; Sckisel, Gail D.; Urayama, Shiro; Monjazeb, Arta M.; Fragoso, Ruben C.; Sayers, Thomas J.; Murphy, William J.

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Alan, Brooks D.; Henrich, Curtis J.; Erickson, Karen L.; Thomas, Cheryl L.; Bokesch, Heidi R.; Tewary, Poonam; Thompson, Candace R.; Pompei, Richard J.; Gustafson, Kirk R.; McMahon, James B.; Sayers, Thomas J.

Impact of Dietary Components on NK and Treg Cell Function for Cancer Prevention

MOLECULAR CARCINOGENESIS

IF3.2

2015-04-01

OAAI

Kim, Young S.; Sayers, Thomas J.; Colburn, Nancy H.; Milner, John A.; Young, Howard A.

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

CELL DEATH & DISEASE

IF9.6

2015-02-26

OAAI

Henrich, C. J.; Brooks, A. D.; Erickson, K. L.; Thomas, C. L.; Bokesch, H. R.; Tewary, P.; Thompson, C. R.; Pompei, R. J.; Gustafson, K. R.; McMahon, J. B.; Sayers, T. J.

Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

BMC CANCER

IF3.4

2014-10-10

OAAI

Canter, Robert J.; Ames, Erik; Mac, Stephanie; Grossenbacher, Steven K.; Chen, Mingyi; Li, Chin-Shang; Borys, Dariusz; Smith, Rachel C.; Tellez, Joe; Sayers, Thomas J.; Monjazeb, Arta M.; Murphy, William J.

Can Nanog activity identify aggressive breast cancer stem cell populations

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Sayers, Thomas J.; de Kluyver, Rachel; Kaddoura, Marcella; Stauffer, Jim; Tewary, Poonam; Brooks, Alan D.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

JOURNAL OF IMMUNOLOGY

IF3.4

2014-06-15

OAAI

Weiss, Jonathan M.; Subleski, Jeff J.; Back, Tim; Chen, Xin; Watkins, Stephanie K.; Yagita, Hideo; Sayers, Thomas J.; Murphy, William J.; Wiltrout, Robert H.

研究方向