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HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded Quitadamo, Briana; Peters, Paul J.; Repik, Alexander; O'Connell, Olivia; Mou, Zhongming; Koch, Matthew; Somasundaran, Mohan; Brody, Robin; Luzuriaga, Katherine; Wallace, Aaron; Wang, Shixia; Lu, Shan; McCauley, Sean; Luban, Jeremy; Duenas-Decamp, Maria; Gonzalez-Perez, Maria Paz; Clapham, Paul R. 分享 收藏
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Screening of primary gp120 immunogens to formulate the next generation polyvalent DNA prime-protein boost HIV-1 vaccines Wang, Shixia; Chou, Te-hui; Hackett, Anthony; Efros, Veronica; Wang, Yan; Han, Dong; Wallace, Aaron; Chen, Yuxin; Hu, Guangnan; Liu, Shuying; Clapham, Paul; Arthos, James; Montefiori, David; Lu, Shan 分享 收藏
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality Beauparlant, David; Rusert, Peter; Magnus, Carsten; Kadelka, Claus; Weber, Jacqueline; Uhr, Therese; Zagordi, Osvaldo; Oberle, Corinna; Duenas-Decamp, Maria J.; Clapham, Paul R.; Metzner, Karin J.; Gunthard, Huldrych F.; Trkola, Alexandra 分享 收藏
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Efficiency of Bridging-Sheet Recruitment Explains HIV-1 R5 Envelope Glycoprotein Sensitivity to Soluble CD4 and Macrophage Tropism O'Connell, Olivia; Repik, Alexander; Reeves, Jacqueline D.; Gonzalez-Perez, Maria Paz; Quitadamo, Briana; Anton, Elizabeth D.; Duenas-Decamp, Maria; Peters, Paul; Lin, Rongheng; Zolla-Pazner, Susan; Corti, Davide; Wallace, Aaron; Wang, Shixia; Kong, Xiang-Peng; Lu, Shan; Clapham, Paul R. 分享 收藏
Intercompartmental Recombination of HIV-1 Contributes to env Intrahost Diversity and Modulates Viral Tropism and Sensitivity to Entry Inhibitors Brown, Richard J. P.; Peters, Paul J.; Caron, Catherine; Gonzalez-Perez, Maria Paz; Stones, Leanne; Ankghuambom, Chiambah; Pondei, Kemebradikumo; McClure, C. Patrick; Alemnji, George; Taylor, Stephen; Sharp, Paul M.; Clapham, Paul R.; Ball, Jonathan K. 分享 收藏
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Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection Shen, Ruizhong; Richter, Holly E.; Clements, Ronald H.; Novak, Lea; Huff, Kayci; Bimczok, Diane; Sankaran-Walters, Sumathi; Dandekar, Satya; Clapham, Paul R.; Smythies, Lesley E.; Smith, Phillip D. 分享 收藏
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Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: Implications for transmission and pathogenesis Peters, Paul J.; Sullivan, W. Matthew; Duenas-Decamp, Maria J.; Bhattacharya, Jayanta; Ankghuambom, Chiambah; Brown, Richard; Luzuriaga, Katherine; Bell, Jeanne; Simmonds, Peter; Ball, Jonathan; Clapham, Paul R. 分享 收藏
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